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Call for Papers - Special Section on the Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities for August 2019

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Towards a combinatorial approach for the prediction of immunoglobulin G half-life and clearance
Dennis R. Goulet, Michael J. Watson, Susan H. Tam, Adam Zwolak, Mark L. Chiu, William M. Atkins and Abhinav Nath

Drug Metabolism and Disposition September 19, 2018, dmd.118.081893; DOI: https://doi.org/10.1124/dmd.118.081893
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Calcitriol and Calcipotriol Modulate Transport Activity of ABC Transporters and Exhibit Selective Cytotoxicity in MRP1-overexpressing Cells
Kee Wee Tan, Angelina Sampson, Bremansu Osa-Andrews and Surtaj Hussain Iram

Drug Metabolism and Disposition September 19, 2018, dmd.118.081612; DOI: https://doi.org/10.1124/dmd.118.081612
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Metabolism of c-Met kinase inhibitors containing quinoline by aldehyde oxidase, electron donating and steric hindrance effect
Jiang Wei Zhang, Wen Xiao, Zhen Ting Gao, Zheng Tian Yu and Ji Yue (Jeff) Zhang

Drug Metabolism and Disposition September 12, 2018, dmd.118.081919; DOI: https://doi.org/10.1124/dmd.118.081919
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6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) is a Highly Selective Substrate for Glucuronidation by Uridine Diphosphoglucuronosyl Transferase (UGT) 1A1, Relative to b-Estradiol
Kimberly Lapham, Jian Lin, Jonathan Novak, Christine Orozco, Mark Niosi, Li Di, Theunis C Goosen, Sangwoo Ryu, Keith Riccardi, Heather Eng, Kimberly O. Cameron and Amit S. Kalgutkar

Drug Metabolism and Disposition September 7, 2018, dmd.118.083709; DOI: https://doi.org/10.1124/dmd.118.083709
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Biotransformation of Finerenone, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, in Dogs, Rats, and Humans, In Vivo and In Vitro
Michael Gerisch, Roland Heinig, Anna Engelen, Dieter Lang, Peter Kolkhof, Martin Radtke, Johannes Platzek, Kai Lovis, Gabriele Rohde and Thomas Schwarz

Drug Metabolism and Disposition September 4, 2018, dmd.118.083337; DOI: https://doi.org/10.1124/dmd.118.083337
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Human Pluripotent Stem Cell Derived Kidney Model for Nephrotoxicity Studies
Piyush Bajaj, A. David Rodrigues, Claire M Steppan, Sandra J Engle, Sumathy Mathialagan and Thomas Schroeter

Drug Metabolism and Disposition August 31, 2018, dmd.118.082727; DOI: https://doi.org/10.1124/dmd.118.082727

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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