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Erratum for Yamazaki et al., Drug Metab Dispos 32 (4) 398-404.
0090-9556/04/3210-1199-$20.00
DMD 32:1199-, 2004

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ERRATUM

CORRECTION TO "COMPARISON OF PREDICTION METHODS FOR IN VIVO CLEARANCE OF (S,S)-3-[3-(METHYLSULFONYL)PHENYL]-1-PROPYLPIPERIDINE HYDROCHLORIDE, A DOPAMINE D2 RECEPTOR ANTAGONIST, IN HUMANS"

In the above article [Yamazaki S, Toth LN, Black ML, and Duncan JN (2004) Drug Metab Dispos 32:398-404], the following errors should be corrected.

On page 403, the sentence "Using the CL x MLP method based on the exponent (0.910) of simple allometry, predicted CLblood value for PNU-96391 was over-predicted by approximately 7-fold despite a high regression coefficient (0.992) across animal species" should be corrected to: "Using the CL x MLP method based on the exponent (0.910) of simple allometry, predicted CLblood value for PNU-96391 was over-predicted by approximately 2-fold despite a high regression coefficient (0.996) across animal species".

On page 403, the sentence "Alternatively the CL x BW method provided an under-prediction (0.4-fold) with a regression coefficient of 0.864" should be corrected to: "Alternatively the CL x BW method provided an over-prediction (1.4-fold) with a regression coefficient of 0.990".

On page 403, the sentence "Thus the in vitro-in vivo correlation approach could predict CLblood value more accurately than the simple allometry or the modified allometric methods" should be corrected to: "Thus the in vitro-in vivo correlation approach could predict CLblood value more accurately than the simple allometry method".

The authors apologize for any confusion and inconvenience caused by these errors.





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