Research ArticleArticle
Glucuronidation of a Sarpogrelate Active Metabolite Is Mediated by UDP-Glucuronosyltransferases 1A4, 1A9, and 2B4
Hyo-Ji Kim, Eun Sook Jeong, Kyung-Ah Seo, Kye Jung Shin, Yeon Jae Choi, Su-Jun Lee, Jong Lyul Ghim, Dong-Ryul Sohn, Jae-Gook Shin and Dong-Hyun Kim
Drug Metabolism and Disposition August 2013, 41 (8) 1529-1537; DOI: https://doi.org/10.1124/dmd.113.051862
Hyo-Ji Kim
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Eun Sook Jeong
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Kyung-Ah Seo
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Kye Jung Shin
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Yeon Jae Choi
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Su-Jun Lee
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Jong Lyul Ghim
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Dong-Ryul Sohn
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Jae-Gook Shin
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
Dong-Hyun Kim
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea (H.-J.K., E.S.J., K.-A.S., S.-J.L., J.L.G., J.-G.S., and D.-H.K.); Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea (K.J.S. and Y.J.C.); and Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Chonan, South Korea (D.-R.S.)
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Research ArticleArticle
UGT Isoforms Involved in Sarpogrelate Metabolite
Hyo-Ji Kim, Eun Sook Jeong, Kyung-Ah Seo, Kye Jung Shin, Yeon Jae Choi, Su-Jun Lee, Jong Lyul Ghim, Dong-Ryul Sohn, Jae-Gook Shin and Dong-Hyun Kim
Drug Metabolism and Disposition August 1, 2013, 41 (8) 1529-1537; DOI: https://doi.org/10.1124/dmd.113.051862
Research ArticleArticle
UGT Isoforms Involved in Sarpogrelate Metabolite
Hyo-Ji Kim, Eun Sook Jeong, Kyung-Ah Seo, Kye Jung Shin, Yeon Jae Choi, Su-Jun Lee, Jong Lyul Ghim, Dong-Ryul Sohn, Jae-Gook Shin and Dong-Hyun Kim
Drug Metabolism and Disposition August 1, 2013, 41 (8) 1529-1537; DOI: https://doi.org/10.1124/dmd.113.051862
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