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AUTOMATED SCREENING WITH CONFIRMATION OF MECHANISM-BASED INACTIVATION OF CYP3A4, CYP2C9, CYP2C19, CYP2D6, AND CYP1A2 IN POOLED HUMAN LIVER MICROSOMES
Drug Metab Dispos Lim et al. 33: 1211

Data Supplement

This article contains 5 data supplements.

Files in this Data Supplement:

Data Supplement - Table 1. Intra- and inter-day assay performance calculated from measurements of inactivation kinetic constants ...
Data Supplement - Table 2. Data (percent of solvent control) from validation of reversibility of inactivation of CYP3A4 and CYP2D6 by oxidation with potassium ferricyanide and dialysis...
Data Supplement - Figure 1 A-C. Data from validation of time- and concentration-dependent inactivation assays ...
Data Supplement - Figure 1 D-E. Data from validation of time- and concentration-dependent inactivation assays...
Data Supplement - Figure 2. Evaluation of ritonavir as mechanism-based inactivation of CYP3A4 by APR screen ...

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