Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions
Drug Metab Dispos Obach et al.
35: 246
Data Supplement
Files in this Data Supplement:
Data Supplement -
Values for kinact and KI were measured for those compounds demonstrating
IC50 shifts, and these are listed in Table 4... The plots for all of the inactivators are contained in Supplemental Information.