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Expression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor ${alpha}$ in Male Rats Fed a High-Fat and High-Sucrose Diet
Drug Metab Dispos Osabe et al. 36: 294

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Data Supplement - Supplemental Table 1 Effect of the high-fat and high-sucrose (HF1) diet and standard (SD) diet on body weight, liver weight, liver lipids, serum lipids, glucose, AST, ALT and gGTP in male and female rats.
Data Supplement - Supplemental Fig. 1 Effects of high-fat and high-sucrose (HF1) diet on expression of drug-metabolizing enzymes in male and female rats fed SD or HF1 diet for 4 weeks. Rats (7 weeks of age) were fed the SD or HF1 diet for 4 weeks and then sacrificed. Total RNA was isolated and analyzed via quantitative real-time polymerase chain reaction as described in Materials and Methods. Relative levels were expressed by taking the control values obtained from SD male animals as 1. Values are the means + S.E. of 5 determinations in each group. *p<0.05, **p<0.01, ***p<0.001 for HF1 male rats versus SD male rats or HF1 female rats versus SD female rats; #p<0.05, ##p<0.01, ###p<0.001 for SD female rats versus SD male rats.

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