Index by author

September 01, 1990; Volume 18,Issue 5

A

  1. Allen, R C

    1. Identification of the urinary metabolites of tacrine in the rat.
      R S Hsu, G M Shutske, E M Dileo, S M Chesson, A R Linville and R C Allen
      Drug Metabolism and Disposition September 1990, 18 (5) 779-783;

  2. Allenby, S M

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

  3. Alonso, I G

    1. Influence of a single dose of ethanol on the kinetics of valproic acid in rats.
      I G Alonso, J M Lanao, M I Martin, A Mateos, A Dominguez-Gil Hurlé and J Fermoso
      Drug Metabolism and Disposition September 1990, 18 (5) 732-734;

  4. Amacher, D E

    1. Metabolism and cytotoxicity of acetaminophen in hepatocyte cultures from rat, rabbit, dog, and monkey.
      T A Smolarek, C V Higgins and D E Amacher
      Drug Metabolism and Disposition September 1990, 18 (5) 659-663;

  5. Andrews, A F

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

B

  1. Badr, M Z

    1. Pharmacokinetics of the anti-AIDS drug 2',3'-dideoxyinosine in the rat.
      G F Ray, W D Mason and M Z Badr
      Drug Metabolism and Disposition September 1990, 18 (5) 654-658;

  2. Baker, M T

    1. Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes.
      M T Baker, M T Vasquez, J N Bates and C K Chiang
      Drug Metabolism and Disposition September 1990, 18 (5) 753-758;

  3. Bates, J N

    1. Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes.
      M T Baker, M T Vasquez, J N Bates and C K Chiang
      Drug Metabolism and Disposition September 1990, 18 (5) 753-758;

  4. Bauer, C

    1. Expressing the specificity and the potency of cytochrome P-450 inducers toward 7-ethoxyresorufin.
      M Paolini, G C Forti and C Bauer
      Drug Metabolism and Disposition September 1990, 18 (5) 551;

  5. Benet, L Z

    1. Covalent binding of zomepirac glucuronide to proteins: evidence for a Schiff base mechanism.
      P C Smith, L Z Benet and A F McDonagh
      Drug Metabolism and Disposition September 1990, 18 (5) 639-644;

  6. Bertrand, M

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

  7. Bevill, R F

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

  8. Bialer, M

    1. Identification of urinary metabolites of cannabidiol in the dog.
      E Samara, M Bialer and D J Harvey
      Drug Metabolism and Disposition September 1990, 18 (5) 571-579;

  9. Biglino, G

    1. Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes.
      O Caputo, G Grosa, M Ceruti, F Rocco and G Biglino
      Drug Metabolism and Disposition September 1990, 18 (5) 771-778;

  10. Bjercke, R J

    1. Interaction of cotinine with rat hepatic microsomal P-450. Comparison with metyrapone and immunomodulation of cotinine and metyrapone binding by monoclonal anti-cotinine antibodies.
      R J Bjercke, D K Hammond, H W Strobel and J J Langone
      Drug Metabolism and Disposition September 1990, 18 (5) 759-764;

  11. Bock, K W

    1. Metabolism of benzene in rat hepatocytes. Influence of inducers on phenol glucuronidation.
      D Schrenk and K W Bock
      Drug Metabolism and Disposition September 1990, 18 (5) 720-725;

  12. Bockx, M

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  13. Bonfils, C

    1. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  14. Bromet, N

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

C

  1. Caputo, O

    1. Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes.
      O Caputo, G Grosa, M Ceruti, F Rocco and G Biglino
      Drug Metabolism and Disposition September 1990, 18 (5) 771-778;

  2. Ceruti, M

    1. Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes.
      O Caputo, G Grosa, M Ceruti, F Rocco and G Biglino
      Drug Metabolism and Disposition September 1990, 18 (5) 771-778;

  3. Chajes, V

    1. Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes.
      J Magdalou, V Chajes, C Lafaurie and G Siest
      Drug Metabolism and Disposition September 1990, 18 (5) 692-697;

  4. Chang, A S

    1. Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.
      A K Cho, M Hiramatsu, E W Distefano, A S Chang and D J Jenden
      Drug Metabolism and Disposition September 1990, 18 (5) 686-691;

  5. Chem, T L

    1. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single i.v. injection in mice.
      T L Chen, P S Miller, P O Ts'o, O M Colvin and T L Chem
      Drug Metabolism and Disposition September 1990, 18 (5) 815-818;

  6. Chen, T L

    1. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single i.v. injection in mice.
      T L Chen, P S Miller, P O Ts'o, O M Colvin and T L Chem
      Drug Metabolism and Disposition September 1990, 18 (5) 815-818;

  7. Chenery, R J

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

  8. Chesson, S M

    1. Identification of the urinary metabolites of tacrine in the rat.
      R S Hsu, G M Shutske, E M Dileo, S M Chesson, A R Linville and R C Allen
      Drug Metabolism and Disposition September 1990, 18 (5) 779-783;

  9. Chiang, C K

    1. Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes.
      M T Baker, M T Vasquez, J N Bates and C K Chiang
      Drug Metabolism and Disposition September 1990, 18 (5) 753-758;

  10. Cho, A K

    1. Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.
      A K Cho, M Hiramatsu, E W Distefano, A S Chang and D J Jenden
      Drug Metabolism and Disposition September 1990, 18 (5) 686-691;

  11. Colvin, O M

    1. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single i.v. injection in mice.
      T L Chen, P S Miller, P O Ts'o, O M Colvin and T L Chem
      Drug Metabolism and Disposition September 1990, 18 (5) 815-818;

  12. Constable, D A

    1. Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes.
      J W Cox, L G Dring, L C Ginsberg, P G Larson, D A Constable and R G Ulrich
      Drug Metabolism and Disposition September 1990, 18 (5) 726-731;

  13. Coon, M J

    1. Induction of cytochrome P-450 isozyme 3a (P-450IIE1) in rabbit olfactory mucosa by ethanol and acetone.
      X X Ding and M J Coon
      Drug Metabolism and Disposition September 1990, 18 (5) 742-745;

  14. Cooper, J K

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  15. Cousins, M J

    1. Influence of isoniazid, phenobarbital, phenytoin, pregnenolone 16-alpha carbonitrile, and beta-naphthoflavone on halothane metabolism and hepatotoxicity.
      M A Jenner, J L Plummer and M J Cousins
      Drug Metabolism and Disposition September 1990, 18 (5) 819-822;

  16. Cox, J W

    1. Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes.
      J W Cox, L G Dring, L C Ginsberg, P G Larson, D A Constable and R G Ulrich
      Drug Metabolism and Disposition September 1990, 18 (5) 726-731;

  17. Cribb, A E

    1. Hepatic microsomal metabolism of sulfamethoxazole to the hydroxylamine.
      A E Cribb and S P Spielberg
      Drug Metabolism and Disposition September 1990, 18 (5) 784-787;

D

  1. Dalet-Beluche, I

    1. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  2. Dileo, E M

    1. Identification of the urinary metabolites of tacrine in the rat.
      R S Hsu, G M Shutske, E M Dileo, S M Chesson, A R Linville and R C Allen
      Drug Metabolism and Disposition September 1990, 18 (5) 779-783;

  3. Ding, X X

    1. Induction of cytochrome P-450 isozyme 3a (P-450IIE1) in rabbit olfactory mucosa by ethanol and acetone.
      X X Ding and M J Coon
      Drug Metabolism and Disposition September 1990, 18 (5) 742-745;

  4. Distefano, E W

    1. Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.
      A K Cho, M Hiramatsu, E W Distefano, A S Chang and D J Jenden
      Drug Metabolism and Disposition September 1990, 18 (5) 686-691;

  5. Domergue, J

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;

  6. Dominguez-Gil Hurlé, A

    1. Influence of a single dose of ethanol on the kinetics of valproic acid in rats.
      I G Alonso, J M Lanao, M I Martin, A Mateos, A Dominguez-Gil Hurlé and J Fermoso
      Drug Metabolism and Disposition September 1990, 18 (5) 732-734;

  7. Dring, L G

    1. Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes.
      J W Cox, L G Dring, L C Ginsberg, P G Larson, D A Constable and R G Ulrich
      Drug Metabolism and Disposition September 1990, 18 (5) 726-731;

F

  1. Fabre, G

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;

  2. Fabre, I

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;
    2. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  3. Ferguson, R J

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

  4. Fermoso, J

    1. Influence of a single dose of ethanol on the kinetics of valproic acid in rats.
      I G Alonso, J M Lanao, M I Martin, A Mateos, A Dominguez-Gil Hurlé and J Fermoso
      Drug Metabolism and Disposition September 1990, 18 (5) 732-734;

  5. Flesher, J W

    1. Metabolism of the carcinogen 3-methylcholanthrene in human bone marrow preparations.
      S R Myers and J W Flesher
      Drug Metabolism and Disposition September 1990, 18 (5) 664-669;

  6. Forti, G C

    1. Expressing the specificity and the potency of cytochrome P-450 inducers toward 7-ethoxyresorufin.
      M Paolini, G C Forti and C Bauer
      Drug Metabolism and Disposition September 1990, 18 (5) 551;

  7. Fujita, S

    1. Age-associated alterations in diazepam metabolizing enzyme activities in male and female rats.
      S Fujita, J Tatsuno, K Kitani and T Suzuki
      Drug Metabolism and Disposition September 1990, 18 (5) 812-814;

G

  1. Gasinska, I

    1. Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat.
      H Hirayama, J Morgado, I Gasinska and K S Pang
      Drug Metabolism and Disposition September 1990, 18 (5) 588-594;

  2. Gele, P

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

  3. Gillet, G

    1. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  4. Gillette, J R

    1. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice.
      K Nagata, B M Martin, J R Gillette and H A Sasame
      Drug Metabolism and Disposition September 1990, 18 (5) 557-564;

  5. Ginsberg, L C

    1. Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes.
      J W Cox, L G Dring, L C Ginsberg, P G Larson, D A Constable and R G Ulrich
      Drug Metabolism and Disposition September 1990, 18 (5) 726-731;

  6. Grislain, L

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

  7. Grosa, G

    1. Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes.
      O Caputo, G Grosa, M Ceruti, F Rocco and G Biglino
      Drug Metabolism and Disposition September 1990, 18 (5) 771-778;

H

  1. Hakusui, H

    1. Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection.
      M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe and M Kanao
      Drug Metabolism and Disposition September 1990, 18 (5) 698-703;

  2. Hammond, D K

    1. Interaction of cotinine with rat hepatic microsomal P-450. Comparison with metyrapone and immunomodulation of cotinine and metyrapone binding by monoclonal anti-cotinine antibodies.
      R J Bjercke, D K Hammond, H W Strobel and J J Langone
      Drug Metabolism and Disposition September 1990, 18 (5) 759-764;

  3. Harrington, G W

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

  4. Harvey, D J

    1. Identification of urinary metabolites of cannabidiol in the dog.
      E Samara, M Bialer and D J Harvey
      Drug Metabolism and Disposition September 1990, 18 (5) 571-579;

  5. Hasegawa, T

    1. Effect of diabetes on disposition and renal handling of cefazolin in rats.
      M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno and S Kitazawa
      Drug Metabolism and Disposition September 1990, 18 (5) 565-570;

  6. Hein, D W

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

  7. Hendrickx, J

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  8. Heykants, J

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  9. Higgins, C V

    1. Metabolism and cytotoxicity of acetaminophen in hepatocyte cultures from rat, rabbit, dog, and monkey.
      T A Smolarek, C V Higgins and D E Amacher
      Drug Metabolism and Disposition September 1990, 18 (5) 659-663;

  10. Hiramatsu, M

    1. Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.
      A K Cho, M Hiramatsu, E W Distefano, A S Chang and D J Jenden
      Drug Metabolism and Disposition September 1990, 18 (5) 686-691;

  11. Hirayama, H

    1. First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once-through vascularly perfused rat intestine-liver preparation.
      H Hirayama and K S Pang
      Drug Metabolism and Disposition September 1990, 18 (5) 580-587;
    2. Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat.
      H Hirayama, J Morgado, I Gasinska and K S Pang
      Drug Metabolism and Disposition September 1990, 18 (5) 588-594;

  12. Hisaka, A

    1. Absorption of a novel prodrug of L-dopa, L-3-(3-hydroxy-4-pivaloyloxyphenyl)alanine (NB-355). In vitro and in situ studies.
      A Hisaka, S Kasamatsu, N Takenaga and M Ohtawa
      Drug Metabolism and Disposition September 1990, 18 (5) 621-625;

  13. Howard, M O

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

  14. Hsu, R S

    1. Identification of the urinary metabolites of tacrine in the rat.
      R S Hsu, G M Shutske, E M Dileo, S M Chesson, A R Linville and R C Allen
      Drug Metabolism and Disposition September 1990, 18 (5) 779-783;

  15. Hubbard, J W

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  16. Hurkmans, R

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  17. Hutchison, M

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

J

  1. James, M O

    1. Bioavailability, metabolism, and renal excretion of benzoic acid in the channel catfish (Ictalurus punctatus).
      S M Plakas and M O James
      Drug Metabolism and Disposition September 1990, 18 (5) 552-556;

  2. Janssen, C

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  3. Jenden, D J

    1. Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.
      A K Cho, M Hiramatsu, E W Distefano, A S Chang and D J Jenden
      Drug Metabolism and Disposition September 1990, 18 (5) 686-691;

  4. Jenner, M A

    1. Influence of isoniazid, phenobarbital, phenytoin, pregnenolone 16-alpha carbonitrile, and beta-naphthoflavone on halothane metabolism and hepatotoxicity.
      M A Jenner, J L Plummer and M J Cousins
      Drug Metabolism and Disposition September 1990, 18 (5) 819-822;

  5. Johno, I

    1. Effect of diabetes on disposition and renal handling of cefazolin in rats.
      M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno and S Kitazawa
      Drug Metabolism and Disposition September 1990, 18 (5) 565-570;

K

  1. Kamoun, A

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

  2. Kanao, M

    1. Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection.
      M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe and M Kanao
      Drug Metabolism and Disposition September 1990, 18 (5) 698-703;

  3. Kasamatsu, S

    1. Absorption of a novel prodrug of L-dopa, L-3-(3-hydroxy-4-pivaloyloxyphenyl)alanine (NB-355). In vitro and in situ studies.
      A Hisaka, S Kasamatsu, N Takenaga and M Ohtawa
      Drug Metabolism and Disposition September 1990, 18 (5) 621-625;

  4. Kemper, C J

    1. Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans.
      J A Scatina, D S Wells, H B Kimmel, C J Kemper and S F Sisenwine
      Drug Metabolism and Disposition September 1990, 18 (5) 746-752;

  5. Kenna, J G

    1. Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane.
      J G Kenna, J L Martin, H Satoh and L R Pohl
      Drug Metabolism and Disposition September 1990, 18 (5) 788-793;

  6. Keohane, D J

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

  7. Kimmel, H B

    1. Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans.
      J A Scatina, D S Wells, H B Kimmel, C J Kemper and S F Sisenwine
      Drug Metabolism and Disposition September 1990, 18 (5) 746-752;

  8. Kirlin, W G

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

  9. Kitani, K

    1. Age-associated alterations in diazepam metabolizing enzyme activities in male and female rats.
      S Fujita, J Tatsuno, K Kitani and T Suzuki
      Drug Metabolism and Disposition September 1990, 18 (5) 812-814;

  10. Kitazawa, S

    1. Effect of diabetes on disposition and renal handling of cefazolin in rats.
      M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno and S Kitazawa
      Drug Metabolism and Disposition September 1990, 18 (5) 565-570;

  11. Korchinski, E D

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  12. Kozeniauskas, R

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

  13. Kumar, R

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  14. Kuzuya, T

    1. Effect of diabetes on disposition and renal handling of cefazolin in rats.
      M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno and S Kitazawa
      Drug Metabolism and Disposition September 1990, 18 (5) 565-570;

L

  1. Lafaurie, C

    1. Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes.
      J Magdalou, V Chajes, C Lafaurie and G Siest
      Drug Metabolism and Disposition September 1990, 18 (5) 692-697;

  2. Lanao, J M

    1. Influence of a single dose of ethanol on the kinetics of valproic acid in rats.
      I G Alonso, J M Lanao, M I Martin, A Mateos, A Dominguez-Gil Hurlé and J Fermoso
      Drug Metabolism and Disposition September 1990, 18 (5) 732-734;

  3. Langone, J J

    1. Interaction of cotinine with rat hepatic microsomal P-450. Comparison with metyrapone and immunomodulation of cotinine and metyrapone binding by monoclonal anti-cotinine antibodies.
      R J Bjercke, D K Hammond, H W Strobel and J J Langone
      Drug Metabolism and Disposition September 1990, 18 (5) 759-764;

  4. Larson, P G

    1. Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes.
      J W Cox, L G Dring, L C Ginsberg, P G Larson, D A Constable and R G Ulrich
      Drug Metabolism and Disposition September 1990, 18 (5) 726-731;

  5. Lauwers, W

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  6. Lavrijsen, K

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  7. Lindstrom, T D

    1. Pharmacokinetics of a novel butylated hydroxytoluene-thiazolidinone CNS antiischemic agent LY256548 in rats, mice, dogs, and monkeys.
      K J Ruterbories and T D Lindstrom
      Drug Metabolism and Disposition September 1990, 18 (5) 674-679;

  8. Linville, A R

    1. Identification of the urinary metabolites of tacrine in the rat.
      R S Hsu, G M Shutske, E M Dileo, S M Chesson, A R Linville and R C Allen
      Drug Metabolism and Disposition September 1990, 18 (5) 779-783;

  9. Luijten, W

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

M

  1. Magdalou, J

    1. Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes.
      J Magdalou, V Chajes, C Lafaurie and G Siest
      Drug Metabolism and Disposition September 1990, 18 (5) 692-697;

  2. Magee, P N

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

  3. Martin, B M

    1. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice.
      K Nagata, B M Martin, J R Gillette and H A Sasame
      Drug Metabolism and Disposition September 1990, 18 (5) 557-564;

  4. Martin, J L

    1. Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane.
      J G Kenna, J L Martin, H Satoh and L R Pohl
      Drug Metabolism and Disposition September 1990, 18 (5) 788-793;

  5. Martin, M I

    1. Influence of a single dose of ethanol on the kinetics of valproic acid in rats.
      I G Alonso, J M Lanao, M I Martin, A Mateos, A Dominguez-Gil Hurlé and J Fermoso
      Drug Metabolism and Disposition September 1990, 18 (5) 732-734;

  6. Mason, W D

    1. Pharmacokinetics of the anti-AIDS drug 2',3'-dideoxyinosine in the rat.
      G F Ray, W D Mason and M Z Badr
      Drug Metabolism and Disposition September 1990, 18 (5) 654-658;
    2. Pharmacokinetics of codeine after parenteral and oral dosing in the rat.
      J Shah and W D Mason
      Drug Metabolism and Disposition September 1990, 18 (5) 670-673;

  7. Mateos, A

    1. Influence of a single dose of ethanol on the kinetics of valproic acid in rats.
      I G Alonso, J M Lanao, M I Martin, A Mateos, A Dominguez-Gil Hurlé and J Fermoso
      Drug Metabolism and Disposition September 1990, 18 (5) 732-734;

  8. Maurel, P

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;
    2. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  9. McDonagh, A F

    1. Covalent binding of zomepirac glucuronide to proteins: evidence for a Schiff base mechanism.
      P C Smith, L Z Benet and A F McDonagh
      Drug Metabolism and Disposition September 1990, 18 (5) 639-644;

  10. McKay, G

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  11. Meuldermans, W

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  12. Midha, K K

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  13. Miller, P S

    1. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single i.v. injection in mice.
      T L Chen, P S Miller, P O Ts'o, O M Colvin and T L Chem
      Drug Metabolism and Disposition September 1990, 18 (5) 815-818;

  14. Morgado, J

    1. Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat.
      H Hirayama, J Morgado, I Gasinska and K S Pang
      Drug Metabolism and Disposition September 1990, 18 (5) 588-594;

  15. Morgan, E T

    1. Pretranslational suppression of cytochrome P-450h (IIC11) gene expression in rat liver after administration of interferon inducers.
      E T Morgan and C A Norman
      Drug Metabolism and Disposition September 1990, 18 (5) 649-653;

  16. Morris, M E

    1. Pharmacokinetics and protein binding of salicylate metabolites in rats.
      M E Morris
      Drug Metabolism and Disposition September 1990, 18 (5) 809-811;

  17. Mourad, G

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;

  18. Mpezo, M

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

  19. Myers, S R

    1. Metabolism of the carcinogen 3-methylcholanthrene in human bone marrow preparations.
      S R Myers and J W Flesher
      Drug Metabolism and Disposition September 1990, 18 (5) 664-669;

  20. Myers, T G

    1. Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.
      M S Rashed, T G Myers and S D Nelson
      Drug Metabolism and Disposition September 1990, 18 (5) 765-770;

N

  1. Nadai, M

    1. Effect of diabetes on disposition and renal handling of cefazolin in rats.
      M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno and S Kitazawa
      Drug Metabolism and Disposition September 1990, 18 (5) 565-570;

  2. Nagata, K

    1. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice.
      K Nagata, B M Martin, J R Gillette and H A Sasame
      Drug Metabolism and Disposition September 1990, 18 (5) 557-564;

  3. Nanavati, N T

    1. Identification and distribution in the rat of acidic metabolites of tamoxifen.
      P C Ruenitz and N T Nanavati
      Drug Metabolism and Disposition September 1990, 18 (5) 645-648;

  4. Nelson, D R

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

  5. Nelson, S D

    1. Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.
      M S Rashed, T G Myers and S D Nelson
      Drug Metabolism and Disposition September 1990, 18 (5) 765-770;

  6. Newton, J F

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

  7. Norman, C A

    1. Pretranslational suppression of cytochrome P-450h (IIC11) gene expression in rat liver after administration of interferon inducers.
      E T Morgan and C A Norman
      Drug Metabolism and Disposition September 1990, 18 (5) 649-653;

O

  1. Ogolla, F

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

  2. Ohtawa, M

    1. Absorption of a novel prodrug of L-dopa, L-3-(3-hydroxy-4-pivaloyloxyphenyl)alanine (NB-355). In vitro and in situ studies.
      A Hisaka, S Kasamatsu, N Takenaga and M Ohtawa
      Drug Metabolism and Disposition September 1990, 18 (5) 621-625;

  3. Ono, K

    1. Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection.
      M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe and M Kanao
      Drug Metabolism and Disposition September 1990, 18 (5) 698-703;

  4. Osborne, P M

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

P

  1. Pang, K S

    1. First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once-through vascularly perfused rat intestine-liver preparation.
      H Hirayama and K S Pang
      Drug Metabolism and Disposition September 1990, 18 (5) 580-587;
    2. Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat.
      H Hirayama, J Morgado, I Gasinska and K S Pang
      Drug Metabolism and Disposition September 1990, 18 (5) 588-594;

  2. Paolini, M

    1. Expressing the specificity and the potency of cytochrome P-450 inducers toward 7-ethoxyresorufin.
      M Paolini, G C Forti and C Bauer
      Drug Metabolism and Disposition September 1990, 18 (5) 551;

  3. Pichard, L

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;
    2. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  4. Plakas, S M

    1. Bioavailability, metabolism, and renal excretion of benzoic acid in the channel catfish (Ictalurus punctatus).
      S M Plakas and M O James
      Drug Metabolism and Disposition September 1990, 18 (5) 552-556;

  5. Plummer, J L

    1. Influence of isoniazid, phenobarbital, phenytoin, pregnenolone 16-alpha carbonitrile, and beta-naphthoflavone on halothane metabolism and hepatotoxicity.
      M A Jenner, J L Plummer and M J Cousins
      Drug Metabolism and Disposition September 1990, 18 (5) 819-822;

  6. Pohl, L R

    1. Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane.
      J G Kenna, J L Martin, H Satoh and L R Pohl
      Drug Metabolism and Disposition September 1990, 18 (5) 788-793;

  7. Pue, M A

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

  8. Pylypiw, H M

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

Q

  1. Qualls, C W

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

R

  1. Rashed, M S

    1. Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.
      M S Rashed, T G Myers and S D Nelson
      Drug Metabolism and Disposition September 1990, 18 (5) 765-770;

  2. Ray, G F

    1. Pharmacokinetics of the anti-AIDS drug 2',3'-dideoxyinosine in the rat.
      G F Ray, W D Mason and M Z Badr
      Drug Metabolism and Disposition September 1990, 18 (5) 654-658;

  3. Rocco, F

    1. Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes.
      O Caputo, G Grosa, M Ceruti, F Rocco and G Biglino
      Drug Metabolism and Disposition September 1990, 18 (5) 771-778;

  4. Ruenitz, P C

    1. Identification and distribution in the rat of acidic metabolites of tamoxifen.
      P C Ruenitz and N T Nanavati
      Drug Metabolism and Disposition September 1990, 18 (5) 645-648;

  5. Ruterbories, K J

    1. Pharmacokinetics of a novel butylated hydroxytoluene-thiazolidinone CNS antiischemic agent LY256548 in rats, mice, dogs, and monkeys.
      K J Ruterbories and T D Lindstrom
      Drug Metabolism and Disposition September 1990, 18 (5) 674-679;

S

  1. Saint Aubert, B

    1. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
      L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 595-606;

  2. Salvadori, C

    1. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.
      L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori and A Kamoun
      Drug Metabolism and Disposition September 1990, 18 (5) 804-808;

  3. Samara, E

    1. Identification of urinary metabolites of cannabidiol in the dog.
      E Samara, M Bialer and D J Harvey
      Drug Metabolism and Disposition September 1990, 18 (5) 571-579;

  4. Sasame, H A

    1. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice.
      K Nagata, B M Martin, J R Gillette and H A Sasame
      Drug Metabolism and Disposition September 1990, 18 (5) 557-564;

  5. Satoh, H

    1. Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane.
      J G Kenna, J L Martin, H Satoh and L R Pohl
      Drug Metabolism and Disposition September 1990, 18 (5) 788-793;

  6. Saverino, C M

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

  7. Scatina, J A

    1. Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans.
      J A Scatina, D S Wells, H B Kimmel, C J Kemper and S F Sisenwine
      Drug Metabolism and Disposition September 1990, 18 (5) 746-752;

  8. Schrenk, D

    1. Metabolism of benzene in rat hepatocytes. Influence of inducers on phenol glucuronidation.
      D Schrenk and K W Bock
      Drug Metabolism and Disposition September 1990, 18 (5) 720-725;

  9. Schwartz, L W

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

  10. Shah, J

    1. Pharmacokinetics of codeine after parenteral and oral dosing in the rat.
      J Shah and W D Mason
      Drug Metabolism and Disposition September 1990, 18 (5) 670-673;

  11. Shepard, T A

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

  12. Shu, Y Z

    1. The identification of urinary metabolites of doxepin in patients.
      Y Z Shu, J W Hubbard, J K Cooper, G McKay, E D Korchinski, R Kumar and K K Midha
      Drug Metabolism and Disposition September 1990, 18 (5) 735-741;

  13. Shutske, G M

    1. Identification of the urinary metabolites of tacrine in the rat.
      R S Hsu, G M Shutske, E M Dileo, S M Chesson, A R Linville and R C Allen
      Drug Metabolism and Disposition September 1990, 18 (5) 779-783;

  14. Siest, G

    1. Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes.
      J Magdalou, V Chajes, C Lafaurie and G Siest
      Drug Metabolism and Disposition September 1990, 18 (5) 692-697;

  15. Sisenwine, S F

    1. Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans.
      J A Scatina, D S Wells, H B Kimmel, C J Kemper and S F Sisenwine
      Drug Metabolism and Disposition September 1990, 18 (5) 746-752;

  16. Smith, P C

    1. Covalent binding of zomepirac glucuronide to proteins: evidence for a Schiff base mechanism.
      P C Smith, L Z Benet and A F McDonagh
      Drug Metabolism and Disposition September 1990, 18 (5) 639-644;

  17. Smolarek, T A

    1. Metabolism and cytotoxicity of acetaminophen in hepatocyte cultures from rat, rabbit, dog, and monkey.
      T A Smolarek, C V Higgins and D E Amacher
      Drug Metabolism and Disposition September 1990, 18 (5) 659-663;

  18. Spielberg, S P

    1. Hepatic microsomal metabolism of sulfamethoxazole to the hydroxylamine.
      A E Cribb and S P Spielberg
      Drug Metabolism and Disposition September 1990, 18 (5) 784-787;

  19. Strobel, H W

    1. Interaction of cotinine with rat hepatic microsomal P-450. Comparison with metyrapone and immunomodulation of cotinine and metyrapone binding by monoclonal anti-cotinine antibodies.
      R J Bjercke, D K Hammond, H W Strobel and J J Langone
      Drug Metabolism and Disposition September 1990, 18 (5) 759-764;

  20. Suzuki, T

    1. Age-associated alterations in diazepam metabolizing enzyme activities in male and female rats.
      S Fujita, J Tatsuno, K Kitani and T Suzuki
      Drug Metabolism and Disposition September 1990, 18 (5) 812-814;

T

  1. Takegoshi, T

    1. Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection.
      M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe and M Kanao
      Drug Metabolism and Disposition September 1990, 18 (5) 698-703;

  2. Takenaga, N

    1. Absorption of a novel prodrug of L-dopa, L-3-(3-hydroxy-4-pivaloyloxyphenyl)alanine (NB-355). In vitro and in situ studies.
      A Hisaka, S Kasamatsu, N Takenaga and M Ohtawa
      Drug Metabolism and Disposition September 1990, 18 (5) 621-625;

  3. Tanaka, M

    1. Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection.
      M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe and M Kanao
      Drug Metabolism and Disposition September 1990, 18 (5) 698-703;

  4. Tatsuno, J

    1. Age-associated alterations in diazepam metabolizing enzyme activities in male and female rats.
      S Fujita, J Tatsuno, K Kitani and T Suzuki
      Drug Metabolism and Disposition September 1990, 18 (5) 812-814;

  5. Thenot, J P

    1. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
      L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, J P Thenot and P Maurel
      Drug Metabolism and Disposition September 1990, 18 (5) 711-719;

  6. Thurmon, J C

    1. The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig.
      G W Harrington, P N Magee, H M Pylypiw, R Kozeniauskas, R F Bevill, D R Nelson and J C Thurmon
      Drug Metabolism and Disposition September 1990, 18 (5) 626-631;

  7. Trinidad, A

    1. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
      F Ogolla, R J Ferguson, W G Kirlin, A Trinidad, A F Andrews, M Mpezo and D W Hein
      Drug Metabolism and Disposition September 1990, 18 (5) 680-685;

  8. Ts'o, P O

    1. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single i.v. injection in mice.
      T L Chen, P S Miller, P O Ts'o, O M Colvin and T L Chem
      Drug Metabolism and Disposition September 1990, 18 (5) 815-818;

U

  1. Ulrich, R G

    1. Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes.
      J W Cox, L G Dring, L C Ginsberg, P G Larson, D A Constable and R G Ulrich
      Drug Metabolism and Disposition September 1990, 18 (5) 726-731;

V

  1. Van Dyck, D

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  2. Van Houdt, J

    1. Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.
      K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans and J Heykants
      Drug Metabolism and Disposition September 1990, 18 (5) 704-710;

  3. Van Loon, J A

    1. Thiopurine methyltransferase isozymes in human renal tissue.
      J A Van Loon and R M Weinshilboum
      Drug Metabolism and Disposition September 1990, 18 (5) 632-638;

  4. Vasquez, M T

    1. Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes.
      M T Baker, M T Vasquez, J N Bates and C K Chiang
      Drug Metabolism and Disposition September 1990, 18 (5) 753-758;

  5. Viney, N J

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

W

  1. Walker, D G

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

  2. Watanabe, Y

    1. Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection.
      M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe and M Kanao
      Drug Metabolism and Disposition September 1990, 18 (5) 698-703;

  3. Webb, A J

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

  4. Weinshilboum, R M

    1. Thiopurine methyltransferase isozymes in human renal tissue.
      J A Van Loon and R M Weinshilboum
      Drug Metabolism and Disposition September 1990, 18 (5) 632-638;

  5. Wells, D S

    1. Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans.
      J A Scatina, D S Wells, H B Kimmel, C J Kemper and S F Sisenwine
      Drug Metabolism and Disposition September 1990, 18 (5) 746-752;

  6. Wood, P J

    1. The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals.
      D G Walker, M Hutchison, T A Shepard, P M Osborne, S M Allenby, A J Webb, N J Viney, M A Pue, R J Chenery and P J Wood
      Drug Metabolism and Disposition September 1990, 18 (5) 613-620;

Y

  1. Yodis, L P

    1. In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole.
      M O Howard, J F Newton, D J Keohane, L P Yodis, C M Saverino, C W Qualls and L W Schwartz
      Drug Metabolism and Disposition September 1990, 18 (5) 607-612;

  2. Yoshizumi, H

    1. Effect of diabetes on disposition and renal handling of cefazolin in rats.
      M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno and S Kitazawa
      Drug Metabolism and Disposition September 1990, 18 (5) 565-570;
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In this issue

Drug Metabolism and Disposition
Vol. 18, Issue 5
1 Sep 1990
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