Drug Metabolism and Disposition: 23 (7)

July 01, 1995; Volume 23,Issue 7

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Antipeptide antibodies against overlapping sequences differentially inhibit human CYP2D6.
A Cribb, C Nuss and R Wang

Drug Metabolism and Disposition July 1995, 23 (7) 671-675;
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Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, an investigational antineoplastic agent, to the dog.
L R Phillips, L Malspeis and J G Supko

Drug Metabolism and Disposition July 1995, 23 (7) 676-680;
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Xenobiotic-enhanced expression of cytochrome P450 2E1 and 2B1/2B2 in primary cultured rat hepatocytes.
R C Zangar, K J Woodcroft, T A Kocarek and R F Novak

Drug Metabolism and Disposition July 1995, 23 (7) 681-687;
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Species differences in the metabolism of a potent HIV-1 reverse transcriptase inhibitor L-738,372. In vivo and in vitro studies in rats, dogs, monkeys, and human.
T Prueksaritanont, S K Balani, L M Dwyer, J D Ellis, L R Kauffman, S L Varga, S M Pitzenberger and A D Theoharides

Drug Metabolism and Disposition July 1995, 23 (7) 688-695;
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cDNA-directed expression of human cytochrome P450 CYP1A1 using baculovirus. Purification, dependency on NADPH-P450 oxidoreductase, and reconstitution of catalytic properties without purification.
J T Buters, M Shou, J P Hardwick, K R Korzekwa and F J Gonzalez

Drug Metabolism and Disposition July 1995, 23 (7) 696-701;
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Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesis.
S L Born, G H John, G R Harlow and J R Halpert

Drug Metabolism and Disposition July 1995, 23 (7) 702-707;
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Comparative ocular pharmacokinetics of brimonidine after a single dose application to the eyes of albino and pigmented rabbits.
A A Acheampong, M Shackleton and D D Tang-Liu

Drug Metabolism and Disposition July 1995, 23 (7) 708-712;
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Plasma and tissue disposition of paclitaxel (taxol) after intraperitoneal administration in mice.
F Innocenti, R Danesi, A Di Paolo, C Agen, D Nardini, G Bocci and M Del Tacca

Drug Metabolism and Disposition July 1995, 23 (7) 713-717;
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Comparative pharmacokinetic/pharmacodynamic study of proton pump inhibitors, omeprazole and lansoprazole in rats.
M Katashima, K Yamamoto, M Sugiura, Y Sawada and T Iga

Drug Metabolism and Disposition July 1995, 23 (7) 718-723;
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Microbial biotransformation of the angiotensin II antagonist GR117289 by Streptomyces rimosus to identify a mammalian metabolite.
R J Cannell, A R Knaggs, M J Dawson, G R Manchee, P J Eddershaw, I Waterhouse, D R Sutherland, G D Bowers and P J Sidebottom

Drug Metabolism and Disposition July 1995, 23 (7) 724-729;
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pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs.
J H Lin, I W Chen, K J Vastag and D Ostovic

Drug Metabolism and Disposition July 1995, 23 (7) 730-735;
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Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
P Bullock, R Pearce, A Draper, J Podval, W Bracken, J Veltman, P Thomas and A Parkinson

Drug Metabolism and Disposition July 1995, 23 (7) 736-748;
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Stereoselectivity and isotope effects associated with cytochrome P450-catalyzed oxidation of (S)-nicotine. The possibility of initial hydrogen atom abstraction in the formation of the delta 1', 5-nicotinium ion.
T J Carlson, J P Jones, L Peterson, N Castagnoli, K R Iyer and W F Trager

Drug Metabolism and Disposition July 1995, 23 (7) 749-756;
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Disposition and cardioselectivity of MDL 74,405, a vitamin E-like free radical scavenger, in rats and dogs after intravenous infusion.
B S Kuo, B S Mathews, J D Stuhler, B K Carrel, J Ho and J Q Rose

Drug Metabolism and Disposition July 1995, 23 (7) 757-764;
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In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.
A D Rodrigues, D J Mulford, R D Lee, B W Surber, M J Kukulka, J L Ferrero, S B Thomas, M S Shet and R W Estabrook

Drug Metabolism and Disposition July 1995, 23 (7) 765-775;
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Interspecies scaling of a thienodiazepine platelet-activating factor receptor antagonist.
C A Elder and M W Modi

Drug Metabolism and Disposition July 1995, 23 (7) 776-778;

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