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Drug Metabolism & Disposition

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Table of Contents

July 01, 1995; Volume 23,Issue 7
  • You have access
    Antipeptide antibodies against overlapping sequences differentially inhibit human CYP2D6.
    A Cribb, C Nuss and R Wang
    Drug Metabolism and Disposition July 1995, 23 (7) 671-675;
  • You have access
    Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, an investigational antineoplastic agent, to the dog.
    L R Phillips, L Malspeis and J G Supko
    Drug Metabolism and Disposition July 1995, 23 (7) 676-680;
  • You have access
    Xenobiotic-enhanced expression of cytochrome P450 2E1 and 2B1/2B2 in primary cultured rat hepatocytes.
    R C Zangar, K J Woodcroft, T A Kocarek and R F Novak
    Drug Metabolism and Disposition July 1995, 23 (7) 681-687;
  • You have access
    Species differences in the metabolism of a potent HIV-1 reverse transcriptase inhibitor L-738,372. In vivo and in vitro studies in rats, dogs, monkeys, and human.
    T Prueksaritanont, S K Balani, L M Dwyer, J D Ellis, L R Kauffman, S L Varga, S M Pitzenberger and A D Theoharides
    Drug Metabolism and Disposition July 1995, 23 (7) 688-695;
  • You have access
    cDNA-directed expression of human cytochrome P450 CYP1A1 using baculovirus. Purification, dependency on NADPH-P450 oxidoreductase, and reconstitution of catalytic properties without purification.
    J T Buters, M Shou, J P Hardwick, K R Korzekwa and F J Gonzalez
    Drug Metabolism and Disposition July 1995, 23 (7) 696-701;
  • You have access
    Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesis.
    S L Born, G H John, G R Harlow and J R Halpert
    Drug Metabolism and Disposition July 1995, 23 (7) 702-707;
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    Comparative ocular pharmacokinetics of brimonidine after a single dose application to the eyes of albino and pigmented rabbits.
    A A Acheampong, M Shackleton and D D Tang-Liu
    Drug Metabolism and Disposition July 1995, 23 (7) 708-712;
  • You have access
    Plasma and tissue disposition of paclitaxel (taxol) after intraperitoneal administration in mice.
    F Innocenti, R Danesi, A Di Paolo, C Agen, D Nardini, G Bocci and M Del Tacca
    Drug Metabolism and Disposition July 1995, 23 (7) 713-717;
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    Comparative pharmacokinetic/pharmacodynamic study of proton pump inhibitors, omeprazole and lansoprazole in rats.
    M Katashima, K Yamamoto, M Sugiura, Y Sawada and T Iga
    Drug Metabolism and Disposition July 1995, 23 (7) 718-723;
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    Microbial biotransformation of the angiotensin II antagonist GR117289 by Streptomyces rimosus to identify a mammalian metabolite.
    R J Cannell, A R Knaggs, M J Dawson, G R Manchee, P J Eddershaw, I Waterhouse, D R Sutherland, G D Bowers and P J Sidebottom
    Drug Metabolism and Disposition July 1995, 23 (7) 724-729;
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    pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs.
    J H Lin, I W Chen, K J Vastag and D Ostovic
    Drug Metabolism and Disposition July 1995, 23 (7) 730-735;
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    Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
    P Bullock, R Pearce, A Draper, J Podval, W Bracken, J Veltman, P Thomas and A Parkinson
    Drug Metabolism and Disposition July 1995, 23 (7) 736-748;
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    Stereoselectivity and isotope effects associated with cytochrome P450-catalyzed oxidation of (S)-nicotine. The possibility of initial hydrogen atom abstraction in the formation of the delta 1', 5-nicotinium ion.
    T J Carlson, J P Jones, L Peterson, N Castagnoli, K R Iyer and W F Trager
    Drug Metabolism and Disposition July 1995, 23 (7) 749-756;
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    Disposition and cardioselectivity of MDL 74,405, a vitamin E-like free radical scavenger, in rats and dogs after intravenous infusion.
    B S Kuo, B S Mathews, J D Stuhler, B K Carrel, J Ho and J Q Rose
    Drug Metabolism and Disposition July 1995, 23 (7) 757-764;
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    In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.
    A D Rodrigues, D J Mulford, R D Lee, B W Surber, M J Kukulka, J L Ferrero, S B Thomas, M S Shet and R W Estabrook
    Drug Metabolism and Disposition July 1995, 23 (7) 765-775;
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    Interspecies scaling of a thienodiazepine platelet-activating factor receptor antagonist.
    C A Elder and M W Modi
    Drug Metabolism and Disposition July 1995, 23 (7) 776-778;
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In this issue

Drug Metabolism and Disposition
Vol. 23, Issue 7
1 Jul 1995
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Pharmacokinetics and Disposition of Biologics
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  • Selective Inhibition of Human CYP2E1 by Clomethiazole
  • Tissue Drug Concentrations: Beyond the Free Drug Hypothesis
  • Liver Zonation Index of Transporters and Enzymes in Mice
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