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Research ArticleArticle

Aldehyde Oxidase-Dependent Marked Species Difference in Hepatic Metabolism of the Sedative-Hypnotic, Zaleplon, Between Monkeys and Rats

Kosuke Kawashima, Kenichi Hosoi, Takeshi Naruke, Toshiharu Shiba, Masataka Kitamura and Tadashi Watabe
Drug Metabolism and Disposition March 1999, 27 (3) 422-428;
Kosuke Kawashima
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Kenichi Hosoi
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Takeshi Naruke
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Toshiharu Shiba
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Masataka Kitamura
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Tadashi Watabe
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Drug Metabolism and Disposition: 27 (3)
Drug Metabolism and Disposition
Vol. 27, Issue 3
1 Mar 1999
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Research ArticleArticle

Aldehyde Oxidase-Dependent Marked Species Difference in Hepatic Metabolism of the Sedative-Hypnotic, Zaleplon, Between Monkeys and Rats

Kosuke Kawashima, Kenichi Hosoi, Takeshi Naruke, Toshiharu Shiba, Masataka Kitamura and Tadashi Watabe
Drug Metabolism and Disposition March 1, 1999, 27 (3) 422-428;

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Research ArticleArticle

Aldehyde Oxidase-Dependent Marked Species Difference in Hepatic Metabolism of the Sedative-Hypnotic, Zaleplon, Between Monkeys and Rats

Kosuke Kawashima, Kenichi Hosoi, Takeshi Naruke, Toshiharu Shiba, Masataka Kitamura and Tadashi Watabe
Drug Metabolism and Disposition March 1, 1999, 27 (3) 422-428;
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  • Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-mediated Uptake
  • Human Cytochrome P450 1A1 Adapts Active Site for Atypical Nonplanar Substrate
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