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Research ArticleArticle

IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM

Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202
Wassim Daher
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Lydie Pelinski
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Sylvie Klieber
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Freddy Sadoun
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Viviane Meunier
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Martine Bourrié
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Christophe Biot
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François Guillou
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Jacques Brocard
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Laurent Fraisse
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Jean-Pierre Maffrand
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Jamal Khalife
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Daniel Dive
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Article Information

vol. 34 no. 4 667-682
DOI 
https://doi.org/10.1124/dmd.104.003202
PubMed 
16415117

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 2, 2004
  • Accepted January 12, 2006
  • Published online March 21, 2006.

Article Versions

  • Earlier version (January 13, 2006 - 11:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Wassim Daher,
  2. Lydie Pelinski,
  3. Sylvie Klieber,
  4. Freddy Sadoun,
  5. Viviane Meunier,
  6. Martine Bourrié,
  7. Christophe Biot,
  8. François Guillou,
  9. Gérard Fabre,
  10. Jacques Brocard,
  11. Laurent Fraisse,
  12. Jean-Pierre Maffrand,
  13. Jamal Khalife and
  14. Daniel Dive
  1. Institut National de la Sante et de la Recherche Medicale U547, Institut Pasteur, Lille, France (W.D., J.K., D.D.); Unité de Catalyse et de Chimie du Solide, Unité Mixte de Recherche Centre National de la Recherche Scientifique 8181, Ecole Nationale Supérieure de Chimie de Lille, Villeneuve d'Ascq, France (L.P., C.B., J.B.); Sanofi-Aventis Recherche, Discovery Metabolism, Pharmacokinetics and Safety Department, Montpellier, France (F.S., V.M., S.K., M.B., F.G., G.F.); and Sanofi-Aventis Recherche, Toulouse, France (L.F., J.-P.M.)
  1. Address correspondence to:
    Daniel Dive, INSERM U547, Institut Pasteur, 1 rue du Professeur P. Calmette, B.P. 245, 59019 Lille Cedex, France. E-mail: daniel.dive{at}pasteur-lille.fr
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Drug Metabolism and Disposition: 34 (4)
Drug Metabolism and Disposition
Vol. 34, Issue 4
1 Apr 2006
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IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
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Research ArticleArticle

IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM

Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
Drug Metabolism and Disposition April 1, 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

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Research ArticleArticle

IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM

Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
Drug Metabolism and Disposition April 1, 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202
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