Index by author
February 01, 2008; Volume 36,Issue 2
A
Acharya, Poulomi
- You have accessKinetic Identification of Membrane Transporters That Assist P-glycoprotein-Mediated Transport of Digoxin and Loperamide through a Confluent Monolayer of MDCKII-hMDR1 CellsPoulomi Acharya, Michael P. O'Connor, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2008, 36 (2) 452-460; DOI: https://doi.org/10.1124/dmd.107.017301
Angus, Derek W.
- You have accessThe Potential Influence of CO2, as an Agent for Euthanasia, on the Pharmacokinetics of Basic Compounds in RodentsDerek W. Angus, James A. Baker, Rona Mason and Iain J. MartinDrug Metabolism and Disposition February 2008, 36 (2) 375-379; DOI: https://doi.org/10.1124/dmd.107.018879
Anzenbacher, Pavel
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Anzenbacherova, Eva
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Asensio, Carine
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Asher, Constance O.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Atwell, Graham J.
- You have accessInfluence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard ProdrugsNuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. TingleDrug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Ayrton, Andrew
- You have accessKinetic Identification of Membrane Transporters That Assist P-glycoprotein-Mediated Transport of Digoxin and Loperamide through a Confluent Monolayer of MDCKII-hMDR1 CellsPoulomi Acharya, Michael P. O'Connor, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2008, 36 (2) 452-460; DOI: https://doi.org/10.1124/dmd.107.017301
B
Bagrel, Denyse
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Baillie, Thomas A.
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Baker, James A.
- You have accessThe Potential Influence of CO2, as an Agent for Euthanasia, on the Pharmacokinetics of Basic Compounds in RodentsDerek W. Angus, James A. Baker, Rona Mason and Iain J. MartinDrug Metabolism and Disposition February 2008, 36 (2) 375-379; DOI: https://doi.org/10.1124/dmd.107.018879
Bandiera, Stelvio M.
- You have accessBiotransformation of Lithocholic Acid by Rat Hepatic Microsomes: Metabolite Analysis by Liquid Chromatography/Mass SpectrometryAnand K. Deo and Stelvio M. BandieraDrug Metabolism and Disposition February 2008, 36 (2) 442-451; DOI: https://doi.org/10.1124/dmd.107.017533
Battaglia, Eric
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Bentz, Joe
- You have accessKinetic Identification of Membrane Transporters That Assist P-glycoprotein-Mediated Transport of Digoxin and Loperamide through a Confluent Monolayer of MDCKII-hMDR1 CellsPoulomi Acharya, Michael P. O'Connor, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2008, 36 (2) 452-460; DOI: https://doi.org/10.1124/dmd.107.017301
Blech, Stefan
- You have accessThe Metabolism and Disposition of the Oral Direct Thrombin Inhibitor, Dabigatran, in HumansStefan Blech, Thomas Ebner, Eva Ludwig-Schwellinger, Joachim Stangier and Willy RothDrug Metabolism and Disposition February 2008, 36 (2) 386-399; DOI: https://doi.org/10.1124/dmd.107.019083
Blomme, Eric A.G.
- You have accessTrovafloxacin-Induced Gene Expression Changes in Liver-Derived in Vitro Systems: Comparison of Primary Human Hepatocytes to HepG2 CellsMichael J. Liguori, Eric A.G. Blomme and Jeffrey F. WaringDrug Metabolism and Disposition February 2008, 36 (2) 223-233; DOI: https://doi.org/10.1124/dmd.107.017608
Bonacorsi, Samuel J.
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Bour, Jérome
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Braun, Matthew P.
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Bridson, William E.
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in HumansPhilip A. Krieter, Mark Gohdes, Timothy J. Musick, Frederick P. Duncanson and William E. BridsonDrug Metabolism and Disposition February 2008, 36 (2) 252-259; DOI: https://doi.org/10.1124/dmd.107.017871
Burysek, Ladislav
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Bush, David
- You have accessCharacterization of 1′-Hydroxymidazolam Glucuronidation in Human Liver MicrosomesBing Zhu, David Bush, George A. Doss, Stella Vincent, Ronald B. Franklin and Shiyao XuDrug Metabolism and Disposition February 2008, 36 (2) 331-338; DOI: https://doi.org/10.1124/dmd.107.017962
C
Cerveny, Lukas
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Chaluvadi, Madhusudana R.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Charles, Kellie A.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Chen, Shiang-Yuan
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Clarke, Stephen J.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
D
Davidson, Ralph E.
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
Dean, Dennis C.
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
de Morais, Sonia M.
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
Deo, Anand K.
- You have accessBiotransformation of Lithocholic Acid by Rat Hepatic Microsomes: Metabolite Analysis by Liquid Chromatography/Mass SpectrometryAnand K. Deo and Stelvio M. BandieraDrug Metabolism and Disposition February 2008, 36 (2) 442-451; DOI: https://doi.org/10.1124/dmd.107.017533
Diaz, Damaris S.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Doss, George A.
- You have accessCharacterization of 1′-Hydroxymidazolam Glucuronidation in Human Liver MicrosomesBing Zhu, David Bush, George A. Doss, Stella Vincent, Ronald B. Franklin and Shiyao XuDrug Metabolism and Disposition February 2008, 36 (2) 331-338; DOI: https://doi.org/10.1124/dmd.107.017962
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Duffy, Andrea
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in the Mouse, Rat, and MonkeyTimothy J. Musick, Mark Gohdes, Andrea Duffy, David A. Erickson and Philip A. KrieterDrug Metabolism and Disposition February 2008, 36 (2) 241-251; DOI: https://doi.org/10.1124/dmd.107.017863
Duncanson, Frederick P.
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in HumansPhilip A. Krieter, Mark Gohdes, Timothy J. Musick, Frederick P. Duncanson and William E. BridsonDrug Metabolism and Disposition February 2008, 36 (2) 252-259; DOI: https://doi.org/10.1124/dmd.107.017871
Dvorak, Zdenek
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
E
Ebert, Bettina
- You have accessSulfotransferase Forms Expressed in Human Intestinal Caco-2 and TC7 Cells at Varying Stages of Differentiation and Role in Benzo[a]pyrene MetabolismWalter Meinl, Bettina Ebert, Hansruedi Glatt and Alfonso LampenDrug Metabolism and Disposition February 2008, 36 (2) 276-283; DOI: https://doi.org/10.1124/dmd.107.018036
Ebner, Thomas
- You have accessThe Metabolism and Disposition of the Oral Direct Thrombin Inhibitor, Dabigatran, in HumansStefan Blech, Thomas Ebner, Eva Ludwig-Schwellinger, Joachim Stangier and Willy RothDrug Metabolism and Disposition February 2008, 36 (2) 386-399; DOI: https://doi.org/10.1124/dmd.107.019083
Ellens, Harma
- You have accessKinetic Identification of Membrane Transporters That Assist P-glycoprotein-Mediated Transport of Digoxin and Loperamide through a Confluent Monolayer of MDCKII-hMDR1 CellsPoulomi Acharya, Michael P. O'Connor, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2008, 36 (2) 452-460; DOI: https://doi.org/10.1124/dmd.107.017301
Erickson, David A.
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in the Mouse, Rat, and MonkeyTimothy J. Musick, Mark Gohdes, Andrea Duffy, David A. Erickson and Philip A. KrieterDrug Metabolism and Disposition February 2008, 36 (2) 241-251; DOI: https://doi.org/10.1124/dmd.107.017863
F
Falkner, K. C.
- You have accessRegulation of the Rat UGT1A6 by Glucocorticoids Involves a Cryptic Glucocorticoid Response ElementK. C. Falkner, J. K. Ritter and R. A. ProughDrug Metabolism and Disposition February 2008, 36 (2) 409-417; DOI: https://doi.org/10.1124/dmd.107.018952
Fardel, Olivier
- You have accessDown-Regulation of Organic Anion Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokine Interleukin 1βMarc Le Vee, Philippe Gripon, Bruno Stieger and Olivier FardelDrug Metabolism and Disposition February 2008, 36 (2) 217-222; DOI: https://doi.org/10.1124/dmd.107.016907
Felmlee, Melanie A.
- You have accessCytochrome P450 Expression and Regulation in CYP3A4/CYP2D6 Double Transgenic Humanized MiceMelanie A. Felmlee, Hoi-Kei Lon, Frank J. Gonzalez and Ai-Ming YuDrug Metabolism and Disposition February 2008, 36 (2) 435-441; DOI: https://doi.org/10.1124/dmd.107.018838
Feng, Bo
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
Franklin, Ronald B.
- You have accessCharacterization of 1′-Hydroxymidazolam Glucuronidation in Human Liver MicrosomesBing Zhu, David Bush, George A. Doss, Stella Vincent, Ronald B. Franklin and Shiyao XuDrug Metabolism and Disposition February 2008, 36 (2) 331-338; DOI: https://doi.org/10.1124/dmd.107.017962
Fujita, Takuya
- You have accessP-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain BarrierAtsushi Ose, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Takuya Fujita, Akira Yamamoto and Yuichi SugiyamaDrug Metabolism and Disposition February 2008, 36 (2) 427-434; DOI: https://doi.org/10.1124/dmd.107.018556
Fujiwara, Ryoichi
- You have accessProduct Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT SubstratesRyoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi YokoiDrug Metabolism and Disposition February 2008, 36 (2) 361-367; DOI: https://doi.org/10.1124/dmd.107.018705
Fukuyama, Tomoaki
- You have accessExpression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose DietMakoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Shin-ichi Ikushiro, Akira Ikari and Masao MiwaDrug Metabolism and Disposition February 2008, 36 (2) 294-302; DOI: https://doi.org/10.1124/dmd.107.017731
G
Ge, Guang-Bo
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Glatt, Hansruedi
- You have accessSulfotransferase Forms Expressed in Human Intestinal Caco-2 and TC7 Cells at Varying Stages of Differentiation and Role in Benzo[a]pyrene MetabolismWalter Meinl, Bettina Ebert, Hansruedi Glatt and Alfonso LampenDrug Metabolism and Disposition February 2008, 36 (2) 276-283; DOI: https://doi.org/10.1124/dmd.107.018036
Gohdes, Mark
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in the Mouse, Rat, and MonkeyTimothy J. Musick, Mark Gohdes, Andrea Duffy, David A. Erickson and Philip A. KrieterDrug Metabolism and Disposition February 2008, 36 (2) 241-251; DOI: https://doi.org/10.1124/dmd.107.017863
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in HumansPhilip A. Krieter, Mark Gohdes, Timothy J. Musick, Frederick P. Duncanson and William E. BridsonDrug Metabolism and Disposition February 2008, 36 (2) 252-259; DOI: https://doi.org/10.1124/dmd.107.017871
Goldthorpe, Michael A.
- You have accessInfluence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard ProdrugsNuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. TingleDrug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Gonzalez, Frank J.
- You have accessCytochrome P450 Expression and Regulation in CYP3A4/CYP2D6 Double Transgenic Humanized MiceMelanie A. Felmlee, Hoi-Kei Lon, Frank J. Gonzalez and Ai-Ming YuDrug Metabolism and Disposition February 2008, 36 (2) 435-441; DOI: https://doi.org/10.1124/dmd.107.018838
Goralski, Kerry B.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Grim, Jiri
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Gripon, Philippe
- You have accessDown-Regulation of Organic Anion Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokine Interleukin 1βMarc Le Vee, Philippe Gripon, Bruno Stieger and Olivier FardelDrug Metabolism and Disposition February 2008, 36 (2) 217-222; DOI: https://doi.org/10.1124/dmd.107.016907
Guillaume, Cécile
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Guo, Jian
- You have accessIn Vitro Metabolism of Isoliquiritigenin by Human Liver MicrosomesJian Guo, Dongting Liu, Dejan Nikolic, Dongwei Zhu, John M. Pezzuto and Richard B. van BreemenDrug Metabolism and Disposition February 2008, 36 (2) 461-468; DOI: https://doi.org/10.1124/dmd.107.018721
H
Hanzawa, Yoshiyuki
- You have accessGenetic Polymorphisms and Haplotype Structures of the Human CYP2W1 Gene in a Japanese PopulationYoshiyuki Hanzawa, Takamitsu Sasaki, Michinao Mizugaki, Masaaki Ishikawa and Masahiro HiratsukaDrug Metabolism and Disposition February 2008, 36 (2) 349-352; DOI: https://doi.org/10.1124/dmd.107.019141
He, Kan
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
He, Yu-Qi
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Helsby, Nuala A.
- You have accessInfluence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard ProdrugsNuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. TingleDrug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Hiratsuka, Masahiro
- You have accessGenetic Polymorphisms and Haplotype Structures of the Human CYP2W1 Gene in a Japanese PopulationYoshiyuki Hanzawa, Takamitsu Sasaki, Michinao Mizugaki, Masaaki Ishikawa and Masahiro HiratsukaDrug Metabolism and Disposition February 2008, 36 (2) 349-352; DOI: https://doi.org/10.1124/dmd.107.019141
I
Ikari, Akira
- You have accessExpression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose DietMakoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Shin-ichi Ikushiro, Akira Ikari and Masao MiwaDrug Metabolism and Disposition February 2008, 36 (2) 294-302; DOI: https://doi.org/10.1124/dmd.107.017731
Ikeda, Toshihiko
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Ikushiro, Shin-ichi
- You have accessExpression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose DietMakoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Shin-ichi Ikushiro, Akira Ikari and Masao MiwaDrug Metabolism and Disposition February 2008, 36 (2) 294-302; DOI: https://doi.org/10.1124/dmd.107.017731
Ishikawa, Masaaki
- You have accessGenetic Polymorphisms and Haplotype Structures of the Human CYP2W1 Gene in a Japanese PopulationYoshiyuki Hanzawa, Takamitsu Sasaki, Michinao Mizugaki, Masaaki Ishikawa and Masahiro HiratsukaDrug Metabolism and Disposition February 2008, 36 (2) 349-352; DOI: https://doi.org/10.1124/dmd.107.019141
Iwabuchi, Haruo
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Iwuchukwu, Otito Frances
- You have accessResveratrol (trans-Resveratrol, 3,5,4′-Trihydroxy-trans-stilbene) Glucuronidation Exhibits Atypical Enzyme Kinetics in Various Protein SourcesOtito Frances Iwuchukwu and Swati NagarDrug Metabolism and Disposition February 2008, 36 (2) 322-330; DOI: https://doi.org/10.1124/dmd.107.018788
J
Jacobus, David. P.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Janiszewski, John S.
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
K
Kacevska, Marina
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Kanai, Motomu
- You have accessP-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain BarrierAtsushi Ose, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Takuya Fujita, Akira Yamamoto and Yuichi SugiyamaDrug Metabolism and Disposition February 2008, 36 (2) 427-434; DOI: https://doi.org/10.1124/dmd.107.018556
Kapoor, Ruchita
- You have accessTransfection of Human Prostate Cancer CA-HPV-10 Cells with Cytosolic Sulfotransferase SULT1E1 Affects Estrogen Signaling and Gene TranscriptionRuchita Kapoor and Jonathan J. ShengDrug Metabolism and Disposition February 2008, 36 (2) 316-321; DOI: https://doi.org/10.1124/dmd.107.017632
Katoh, Miki
- You have accessProduct Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT SubstratesRyoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi YokoiDrug Metabolism and Disposition February 2008, 36 (2) 361-367; DOI: https://doi.org/10.1124/dmd.107.018705
Kirsch, Glbert
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Knabb, Robert M.
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Knudsen, G. A.
- You have accessThe Effects of Dose and Route on the Toxicokinetics and Disposition of 1-Butyl-3-methylimidazolium Chloride in Male F-344 Rats and Female B6C3F1 MiceI. G. Sipes, G. A. Knudsen and R. K. KuesterDrug Metabolism and Disposition February 2008, 36 (2) 284-293; DOI: https://doi.org/10.1124/dmd.107.018515
Ko, Nga Ling
- You have accessPharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the RatRu Yan, Nga Ling Ko, Song-Lin Li, Yun Kau Tam and Ge LinDrug Metabolism and Disposition February 2008, 36 (2) 400-408; DOI: https://doi.org/10.1124/dmd.107.017707
Kozar, Michael. P.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Krieter, Philip A.
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in the Mouse, Rat, and MonkeyTimothy J. Musick, Mark Gohdes, Andrea Duffy, David A. Erickson and Philip A. KrieterDrug Metabolism and Disposition February 2008, 36 (2) 241-251; DOI: https://doi.org/10.1124/dmd.107.017863
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in HumansPhilip A. Krieter, Mark Gohdes, Timothy J. Musick, Frederick P. Duncanson and William E. BridsonDrug Metabolism and Disposition February 2008, 36 (2) 252-259; DOI: https://doi.org/10.1124/dmd.107.017871
Kuester, R. K.
- You have accessThe Effects of Dose and Route on the Toxicokinetics and Disposition of 1-Butyl-3-methylimidazolium Chloride in Male F-344 Rats and Female B6C3F1 MiceI. G. Sipes, G. A. Knudsen and R. K. KuesterDrug Metabolism and Disposition February 2008, 36 (2) 284-293; DOI: https://doi.org/10.1124/dmd.107.018515
Kunes, Jiri
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Kusuhara, Hiroyuki
- You have accessP-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain BarrierAtsushi Ose, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Takuya Fujita, Akira Yamamoto and Yuichi SugiyamaDrug Metabolism and Disposition February 2008, 36 (2) 427-434; DOI: https://doi.org/10.1124/dmd.107.018556
L
Lam, Patrick Y. S.
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Lampen, Alfonso
- You have accessSulfotransferase Forms Expressed in Human Intestinal Caco-2 and TC7 Cells at Varying Stages of Differentiation and Role in Benzo[a]pyrene MetabolismWalter Meinl, Bettina Ebert, Hansruedi Glatt and Alfonso LampenDrug Metabolism and Disposition February 2008, 36 (2) 276-283; DOI: https://doi.org/10.1124/dmd.107.018036
Lapicque, Françoise
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Lecureux, Lloyd
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Le Vee, Marc
- You have accessDown-Regulation of Organic Anion Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokine Interleukin 1βMarc Le Vee, Philippe Gripon, Bruno Stieger and Olivier FardelDrug Metabolism and Disposition February 2008, 36 (2) 217-222; DOI: https://doi.org/10.1124/dmd.107.016907
Li, Song-Lin
- You have accessPharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the RatRu Yan, Nga Ling Ko, Song-Lin Li, Yun Kau Tam and Ge LinDrug Metabolism and Disposition February 2008, 36 (2) 400-408; DOI: https://doi.org/10.1124/dmd.107.017707
Li, Wei
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Li, Yan
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Li, Ying
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Liddle, Christopher
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Liguori, Michael J.
- You have accessTrovafloxacin-Induced Gene Expression Changes in Liver-Derived in Vitro Systems: Comparison of Primary Human Hepatocytes to HepG2 CellsMichael J. Liguori, Eric A.G. Blomme and Jeffrey F. WaringDrug Metabolism and Disposition February 2008, 36 (2) 223-233; DOI: https://doi.org/10.1124/dmd.107.017608
Lin, Ge
- You have accessPharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the RatRu Yan, Nga Ling Ko, Song-Lin Li, Yun Kau Tam and Ge LinDrug Metabolism and Disposition February 2008, 36 (2) 400-408; DOI: https://doi.org/10.1124/dmd.107.017707
Liu, Dongting
- You have accessIn Vitro Metabolism of Isoliquiritigenin by Human Liver MicrosomesJian Guo, Dongting Liu, Dejan Nikolic, Dongwei Zhu, John M. Pezzuto and Richard B. van BreemenDrug Metabolism and Disposition February 2008, 36 (2) 461-468; DOI: https://doi.org/10.1124/dmd.107.018721
Liu, Xing-Bao
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Liu, Yong
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Lon, Hoi-Kei
- You have accessCytochrome P450 Expression and Regulation in CYP3A4/CYP2D6 Double Transgenic Humanized MiceMelanie A. Felmlee, Hoi-Kei Lon, Frank J. Gonzalez and Ai-Ming YuDrug Metabolism and Disposition February 2008, 36 (2) 435-441; DOI: https://doi.org/10.1124/dmd.107.018838
Ludwig-Schwellinger, Eva
- You have accessThe Metabolism and Disposition of the Oral Direct Thrombin Inhibitor, Dabigatran, in HumansStefan Blech, Thomas Ebner, Eva Ludwig-Schwellinger, Joachim Stangier and Willy RothDrug Metabolism and Disposition February 2008, 36 (2) 386-399; DOI: https://doi.org/10.1124/dmd.107.019083
M
Martin, Iain J.
- You have accessThe Potential Influence of CO2, as an Agent for Euthanasia, on the Pharmacokinetics of Basic Compounds in RodentsDerek W. Angus, James A. Baker, Rona Mason and Iain J. MartinDrug Metabolism and Disposition February 2008, 36 (2) 375-379; DOI: https://doi.org/10.1124/dmd.107.018879
Mason, Rona
- You have accessThe Potential Influence of CO2, as an Agent for Euthanasia, on the Pharmacokinetics of Basic Compounds in RodentsDerek W. Angus, James A. Baker, Rona Mason and Iain J. MartinDrug Metabolism and Disposition February 2008, 36 (2) 375-379; DOI: https://doi.org/10.1124/dmd.107.018879
Maunit, Benoît
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Meinl, Walter
- You have accessSulfotransferase Forms Expressed in Human Intestinal Caco-2 and TC7 Cells at Varying Stages of Differentiation and Role in Benzo[a]pyrene MetabolismWalter Meinl, Bettina Ebert, Hansruedi Glatt and Alfonso LampenDrug Metabolism and Disposition February 2008, 36 (2) 276-283; DOI: https://doi.org/10.1124/dmd.107.018036
Mikamoto, Kei
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Milhous, Wilbur. K.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Mills, Jessica B.
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
Mireles, Rouchelle J.
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
Miwa, Masao
- You have accessExpression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose DietMakoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Shin-ichi Ikushiro, Akira Ikari and Masao MiwaDrug Metabolism and Disposition February 2008, 36 (2) 294-302; DOI: https://doi.org/10.1124/dmd.107.017731
Mizugaki, Michinao
- You have accessGenetic Polymorphisms and Haplotype Structures of the Human CYP2W1 Gene in a Japanese PopulationYoshiyuki Hanzawa, Takamitsu Sasaki, Michinao Mizugaki, Masaaki Ishikawa and Masahiro HiratsukaDrug Metabolism and Disposition February 2008, 36 (2) 349-352; DOI: https://doi.org/10.1124/dmd.107.019141
Morgan, Edward T.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Muller, Jean-François
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Murai, Takahiro
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Musick, Timothy J.
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in the Mouse, Rat, and MonkeyTimothy J. Musick, Mark Gohdes, Andrea Duffy, David A. Erickson and Philip A. KrieterDrug Metabolism and Disposition February 2008, 36 (2) 241-251; DOI: https://doi.org/10.1124/dmd.107.017863
- You have accessPharmacokinetics, Disposition, and Metabolism of Bicifadine in HumansPhilip A. Krieter, Mark Gohdes, Timothy J. Musick, Frederick P. Duncanson and William E. BridsonDrug Metabolism and Disposition February 2008, 36 (2) 252-259; DOI: https://doi.org/10.1124/dmd.107.017871
N
Nagar, Swati
- You have accessResveratrol (trans-Resveratrol, 3,5,4′-Trihydroxy-trans-stilbene) Glucuronidation Exhibits Atypical Enzyme Kinetics in Various Protein SourcesOtito Frances Iwuchukwu and Swati NagarDrug Metabolism and Disposition February 2008, 36 (2) 322-330; DOI: https://doi.org/10.1124/dmd.107.018788
Nakajima, Miki
- You have accessProduct Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT SubstratesRyoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi YokoiDrug Metabolism and Disposition February 2008, 36 (2) 361-367; DOI: https://doi.org/10.1124/dmd.107.018705
Netter, Patrick
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Nikolic, Dejan
- You have accessIn Vitro Metabolism of Isoliquiritigenin by Human Liver MicrosomesJian Guo, Dongting Liu, Dejan Nikolic, Dongwei Zhu, John M. Pezzuto and Richard B. van BreemenDrug Metabolism and Disposition February 2008, 36 (2) 461-468; DOI: https://doi.org/10.1124/dmd.107.018721
Nitanai, Takashi
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
O
O'Connor, Michael P.
- You have accessKinetic Identification of Membrane Transporters That Assist P-glycoprotein-Mediated Transport of Digoxin and Loperamide through a Confluent Monolayer of MDCKII-hMDR1 CellsPoulomi Acharya, Michael P. O'Connor, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2008, 36 (2) 452-460; DOI: https://doi.org/10.1124/dmd.107.017301
Osabe, Makoto
- You have accessExpression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose DietMakoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Shin-ichi Ikushiro, Akira Ikari and Masao MiwaDrug Metabolism and Disposition February 2008, 36 (2) 294-302; DOI: https://doi.org/10.1124/dmd.107.017731
Osbild, Sandra
- You have accessInteraction of the Electrophilic Ketoprofenyl-Glucuronide and Ketoprofenyl-Coenzyme A Conjugates with Cytosolic Glutathione S-TransferasesSandra Osbild, Jérome Bour, Benoît Maunit, Cécile Guillaume, Carine Asensio, Jean-François Muller, Patrick Netter, Glbert Kirsch, Denyse Bagrel, Françoise Lapicque and Eric BattagliaDrug Metabolism and Disposition February 2008, 36 (2) 260-267; DOI: https://doi.org/10.1124/dmd.107.016808
Ose, Atsushi
- You have accessP-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain BarrierAtsushi Ose, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Takuya Fujita, Akira Yamamoto and Yuichi SugiyamaDrug Metabolism and Disposition February 2008, 36 (2) 427-434; DOI: https://doi.org/10.1124/dmd.107.018556
Osorio-Lozada, Antonio
- You have accessBiosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes SpeciesAntonio Osorio-Lozada, Sekhar Surapaneni, Gary L. Skiles and Raju SubramanianDrug Metabolism and Disposition February 2008, 36 (2) 234-240; DOI: https://doi.org/10.1124/dmd.107.019323
P
Patrone, Laura M.
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Pavek, Petr
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Pezzuto, John M.
- You have accessIn Vitro Metabolism of Isoliquiritigenin by Human Liver MicrosomesJian Guo, Dongting Liu, Dejan Nikolic, Dongwei Zhu, John M. Pezzuto and Richard B. van BreemenDrug Metabolism and Disposition February 2008, 36 (2) 461-468; DOI: https://doi.org/10.1124/dmd.107.018721
Piquette-Miller, Micheline
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Polli, Joseph W.
- You have accessKinetic Identification of Membrane Transporters That Assist P-glycoprotein-Mediated Transport of Digoxin and Loperamide through a Confluent Monolayer of MDCKII-hMDR1 CellsPoulomi Acharya, Michael P. O'Connor, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2008, 36 (2) 452-460; DOI: https://doi.org/10.1124/dmd.107.017301
Pour, Milan
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Prough, R. A.
- You have accessRegulation of the Rat UGT1A6 by Glucocorticoids Involves a Cryptic Glucocorticoid Response ElementK. C. Falkner, J. K. Ritter and R. A. ProughDrug Metabolism and Disposition February 2008, 36 (2) 409-417; DOI: https://doi.org/10.1124/dmd.107.018952
Q
Quan, Mimi
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
R
Raghavan, Nirmala
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Renton, Kenneth W.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Richardson, Terrilyn A.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Ritter, J. K.
- You have accessRegulation of the Rat UGT1A6 by Glucocorticoids Involves a Cryptic Glucocorticoid Response ElementK. C. Falkner, J. K. Ritter and R. A. ProughDrug Metabolism and Disposition February 2008, 36 (2) 409-417; DOI: https://doi.org/10.1124/dmd.107.018952
Robertson, Graham R.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Roth, Willy
- You have accessThe Metabolism and Disposition of the Oral Direct Thrombin Inhibitor, Dabigatran, in HumansStefan Blech, Thomas Ebner, Eva Ludwig-Schwellinger, Joachim Stangier and Willy RothDrug Metabolism and Disposition February 2008, 36 (2) 386-399; DOI: https://doi.org/10.1124/dmd.107.019083
S
Samata, Naozumi
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Sasaki, Takamitsu
- You have accessGenetic Polymorphisms and Haplotype Structures of the Human CYP2W1 Gene in a Japanese PopulationYoshiyuki Hanzawa, Takamitsu Sasaki, Michinao Mizugaki, Masaaki Ishikawa and Masahiro HiratsukaDrug Metabolism and Disposition February 2008, 36 (2) 349-352; DOI: https://doi.org/10.1124/dmd.107.019141
Schiehser, Guy A.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Sharma, Rohini
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Shearer, Todd. W.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Sheng, Jonathan J.
- You have accessTransfection of Human Prostate Cancer CA-HPV-10 Cells with Cytosolic Sulfotransferase SULT1E1 Affects Estrogen Signaling and Gene TranscriptionRuchita Kapoor and Jonathan J. ShengDrug Metabolism and Disposition February 2008, 36 (2) 316-321; DOI: https://doi.org/10.1124/dmd.107.017632
Shibasaki, Masakatsu
- You have accessP-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain BarrierAtsushi Ose, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Takuya Fujita, Akira Yamamoto and Yuichi SugiyamaDrug Metabolism and Disposition February 2008, 36 (2) 427-434; DOI: https://doi.org/10.1124/dmd.107.018556
Sinal, Christopher J.
- You have accessRegulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and CancerEdward T. Morgan, Kerry B. Goralski, Micheline Piquette-Miller, Kenneth W. Renton, Graham R. Robertson, Madhusudana R. Chaluvadi, Kellie A. Charles, Stephen J. Clarke, Marina Kacevska, Christopher Liddle, Terrilyn A. Richardson, Rohini Sharma and Christopher J. SinalDrug Metabolism and Disposition February 2008, 36 (2) 205-216; DOI: https://doi.org/10.1124/dmd.107.018747
Sipes, I. G.
- You have accessThe Effects of Dose and Route on the Toxicokinetics and Disposition of 1-Butyl-3-methylimidazolium Chloride in Male F-344 Rats and Female B6C3F1 MiceI. G. Sipes, G. A. Knudsen and R. K. KuesterDrug Metabolism and Disposition February 2008, 36 (2) 284-293; DOI: https://doi.org/10.1124/dmd.107.018515
Skiles, Gary L.
- You have accessBiosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes SpeciesAntonio Osorio-Lozada, Sekhar Surapaneni, Gary L. Skiles and Raju SubramanianDrug Metabolism and Disposition February 2008, 36 (2) 234-240; DOI: https://doi.org/10.1124/dmd.107.019323
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
Skillman, Donald. R.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Slatter, J. Greg
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Smith, Eileen M.
- You have accessInfluence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard ProdrugsNuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. TingleDrug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Smith, Kirsten S.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Sousa, Jason C.
- You have accessRole of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial DihydrotriazinesDamaris S. Diaz, Michael. P. Kozar, Kirsten S. Smith, Constance O. Asher, Jason C. Sousa, Guy A. Schiehser, David. P. Jacobus, Wilbur. K. Milhous, Donald. R. Skillman and Todd. W. ShearerDrug Metabolism and Disposition February 2008, 36 (2) 380-385; DOI: https://doi.org/10.1124/dmd.106.013920
Stangier, Joachim
- You have accessThe Metabolism and Disposition of the Oral Direct Thrombin Inhibitor, Dabigatran, in HumansStefan Blech, Thomas Ebner, Eva Ludwig-Schwellinger, Joachim Stangier and Willy RothDrug Metabolism and Disposition February 2008, 36 (2) 386-399; DOI: https://doi.org/10.1124/dmd.107.019083
Staud, Frantisek
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Stearns, Ralph A.
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Stieger, Bruno
- You have accessDown-Regulation of Organic Anion Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokine Interleukin 1βMarc Le Vee, Philippe Gripon, Bruno Stieger and Olivier FardelDrug Metabolism and Disposition February 2008, 36 (2) 217-222; DOI: https://doi.org/10.1124/dmd.107.016907
Subramanian, Raju
- You have accessBiosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes SpeciesAntonio Osorio-Lozada, Sekhar Surapaneni, Gary L. Skiles and Raju SubramanianDrug Metabolism and Disposition February 2008, 36 (2) 234-240; DOI: https://doi.org/10.1124/dmd.107.019323
Sugatani, Junko
- You have accessExpression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose DietMakoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Shin-ichi Ikushiro, Akira Ikari and Masao MiwaDrug Metabolism and Disposition February 2008, 36 (2) 294-302; DOI: https://doi.org/10.1124/dmd.107.017731
Sugiyama, Yuichi
- You have accessP-glycoprotein Restricts the Penetration of Oseltamivir Across the Blood-Brain BarrierAtsushi Ose, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Takuya Fujita, Akira Yamamoto and Yuichi SugiyamaDrug Metabolism and Disposition February 2008, 36 (2) 427-434; DOI: https://doi.org/10.1124/dmd.107.018556
Sun, Jie
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Surapaneni, Sekhar
- You have accessBiosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes SpeciesAntonio Osorio-Lozada, Sekhar Surapaneni, Gary L. Skiles and Raju SubramanianDrug Metabolism and Disposition February 2008, 36 (2) 234-240; DOI: https://doi.org/10.1124/dmd.107.019323
Svecova, Lucie
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
T
Takei, Makoto
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Tam, Yun Kau
- You have accessPharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the RatRu Yan, Nga Ling Ko, Song-Lin Li, Yun Kau Tam and Ge LinDrug Metabolism and Disposition February 2008, 36 (2) 400-408; DOI: https://doi.org/10.1124/dmd.107.017707
Tanaka, Kohji
- You have accessIsolation and Identification of Diglucuronides of Some Endogenous Steroids in DogsTakahiro Murai, Naotoshi Yamamura, Takashi Nitanai, Naozumi Samata, Makoto Takei, Haruo Iwabuchi, Kohji Tanaka, Kei Mikamoto and Toshihiko IkedaDrug Metabolism and Disposition February 2008, 36 (2) 368-374; DOI: https://doi.org/10.1124/dmd.107.019059
Tang, Magdalene H. Y.
- You have accessInfluence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard ProdrugsNuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. TingleDrug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Tang, Wei
- You have accessIn Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver PreparationsYing Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie and Wei TangDrug Metabolism and Disposition February 2008, 36 (2) 469-473; DOI: https://doi.org/10.1124/dmd.107.019018
Tingle, Malcolm D.
- You have accessInfluence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard ProdrugsNuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. TingleDrug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Trejtnar, Frantisek
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Troutman, Matthew D.
- You have accessIn Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous SystemBo Feng, Jessica B. Mills, Ralph E. Davidson, Rouchelle J. Mireles, John S. Janiszewski, Matthew D. Troutman and Sonia M. de MoraisDrug Metabolism and Disposition February 2008, 36 (2) 268-275; DOI: https://doi.org/10.1124/dmd.107.017434
V
van Breemen, Richard B.
- You have accessIn Vitro Metabolism of Isoliquiritigenin by Human Liver MicrosomesJian Guo, Dongting Liu, Dejan Nikolic, Dongwei Zhu, John M. Pezzuto and Richard B. van BreemenDrug Metabolism and Disposition February 2008, 36 (2) 461-468; DOI: https://doi.org/10.1124/dmd.107.018721
Vincent, Stella
- You have accessCharacterization of 1′-Hydroxymidazolam Glucuronidation in Human Liver MicrosomesBing Zhu, David Bush, George A. Doss, Stella Vincent, Ronald B. Franklin and Shiyao XuDrug Metabolism and Disposition February 2008, 36 (2) 331-338; DOI: https://doi.org/10.1124/dmd.107.017962
Vrzal, Radim
- You have accessAzole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene ExpressionLucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr PavekDrug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
W
Wang, Li-Ming
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Wang, Zheng-Tao
- You have accessTaxane's Substituents at C3′ Affect Its Regioselective Metabolism: Different in Vitro Metabolism of Cephalomannine and PaclitaxelJiang-Wei Zhang, Guang-Bo Ge, Yong Liu, Li-Ming Wang, Xing-Bao Liu, Yan-Yan Zhang, Wei Li, Yu-Qi He, Zheng-Tao Wang, Jie Sun, Hong-Bin Xiao and Ling YangDrug Metabolism and Disposition February 2008, 36 (2) 418-426; DOI: https://doi.org/10.1124/dmd.107.018242
Waring, Jeffrey F.
- You have accessTrovafloxacin-Induced Gene Expression Changes in Liver-Derived in Vitro Systems: Comparison of Primary Human Hepatocytes to HepG2 CellsMichael J. Liguori, Eric A.G. Blomme and Jeffrey F. WaringDrug Metabolism and Disposition February 2008, 36 (2) 223-233; DOI: https://doi.org/10.1124/dmd.107.017608
Wilson, William R.
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Yamamoto, Akira
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Yamamura, Naotoshi
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Yamanaka, Hiroyuki
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Yamatsugu, Kenzo
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Yokoi, Tsuyoshi
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Yu, Ai-Ming
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Zhang, Donglu
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Zhang, Haiying
- You have accessReductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and DogsDonglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan HeDrug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416
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Zhang, Yan-Yan
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Zhu, Bing
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