Research ArticleArticle
The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885