Index by author
March 01, 2010; Volume 38,Issue 3
A
Andersson, Tommy B.
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
Anthérieu, Sébastien
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Argikar, Upendra A.
- You have accessIdentification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic StudiesMithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn HarrimanDrug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
Atwell, Graham J.
- You have accessMetabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and HumansYongchuan Gu, Graham J. Atwell and William R. WilsonDrug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973
B
Baeschlin, Daniel
- You have accessIdentification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic StudiesMithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn HarrimanDrug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
Balliet, Rene M.
- You have accessUDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer SusceptibilityRene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip LazarusDrug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
Bergman, Arthur J.
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Biddle, Zachary
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Bischoff, Daniel
- You have accessGlucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombeCălin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias BureikDrug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
Boisvert, Caroline
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
Bradley, Scott
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
Braun, Matthew P.
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Buchheit, Daniela
- You have accessGlucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombeCălin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias BureikDrug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
Bureik, Matthias
- You have accessGlucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombeCălin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias BureikDrug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
C
Cai, Hong
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Camus, Sandrine
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Cavaco, Isa
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
Chen, Feng
- You have accessComment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng ChenDrug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
Chen, Gang
- You have accessUDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer SusceptibilityRene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip LazarusDrug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
Chen, Mei
- You have accessIdentification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of ChloramphenicolMei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. WilliamsDrug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
Chen, Qing
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
Chen, Shiang-yuan
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Chesné, Christophe
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Chong, Saeho
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Court, Michael H.
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
D
Dani, Mélina
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
Darnell, Malin
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
Dean, Dennis C.
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Dellinger, Ryan W.
- You have accessUDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer SusceptibilityRene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip LazarusDrug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
Discenza, L.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Doss, George
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
Drăgan, Călin-Aurel
- You have accessGlucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombeCălin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias BureikDrug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
Dru, James
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
E
Ebner, Thomas
- You have accessGlucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombeCălin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias BureikDrug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
Ellsworth, B. A.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
F
Feenstra, Kenneth L.
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Felmlee, Melanie A.
- You have accessMonocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 CellsWing Ki Lam, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
Ferreira, Suzie
- You have accessIdentification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic StudiesMithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn HarrimanDrug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
Finel, Moshe
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
Frost, Charles A.
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Fukamizu, Akiyoshi
- You have accessExpressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude MiceMichiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu YoshimuraDrug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
G
Gagne, Jason
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Gendrano, Isaias Noel
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Goosen, Theunis C.
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Graves, Mark W.
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Griffith, W. Humphreys
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Grossman, Scott J.
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Gu, Yongchuan
- You have accessMetabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and HumansYongchuan Gu, Graham J. Atwell and William R. WilsonDrug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973
Guguen-Guillouzo, Christiane
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Guillouzo, André
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Gunduz, Mithat
- You have accessIdentification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic StudiesMithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn HarrimanDrug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
H
Harper, Timothy W.
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Harriman, Shawn
- You have accessIdentification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic StudiesMithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn HarrimanDrug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
Hartmann, Georgy
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
He, Kan
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Hidalgo, Ismael J.
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
Ho, Jonathan Z.
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Hofmann, Yvonne
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
Höglund, Camilla
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
Hosagrahara, Vinayak
- You have accessIdentification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic StudiesMithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn HarrimanDrug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
Howe, David
- You have accessIdentification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of ChloramphenicolMei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. WilliamsDrug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
Hsueh, Mei-Mann
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Hu, Zhe-Yi
- You have accessComment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng ChenDrug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
Humphreys, W. G.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
I
Ingelman-Sundberg, Magnus
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
J
Jensen, Klaus Gjervig
- You have accessIdentification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based SimulatorJakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian LinnetDrug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
Jiang, Rong-Rong
- You have accessComment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng ChenDrug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
Johnson, Stephen
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Jones, Allen N.
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Jornil, Jakob
- You have accessIdentification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based SimulatorJakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian LinnetDrug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
K
Kadowaki, Tadashi
- You have accessExpressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude MiceMichiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu YoshimuraDrug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
Karanam, Bindhu
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Karlsson, Johan E.
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
Kasichayanula, S.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Kerr, Stephen
- You have accessIdentification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of ChloramphenicolMei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. WilliamsDrug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
Khanna, A.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Komoroski, B.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Koplowitz, B.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Krishna, Rajesh
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Kumar, Sanjeev
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Kurkela, Mika
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
Kusano, Kazutomi
- You have accessExpressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude MiceMichiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu YoshimuraDrug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
L
Lahoz, Agustin
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Lam, Wing Ki
- You have accessMonocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 CellsWing Ki Lam, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
Landman, Ellie
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
Larsen, Frank
- You have accessIdentification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based SimulatorJakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian LinnetDrug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
Lazarus, Philip
- You have accessUDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer SusceptibilityRene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip LazarusDrug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
Leblond, Francois A.
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
LeDuc, Barbara
- You have accessIdentification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of ChloramphenicolMei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. WilliamsDrug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
Lefrançois, Stéphane
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
Li, Jibin
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
Li, Ruoya
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Li, W.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Linnet, Kristian
- You have accessIdentification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based SimulatorJakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian LinnetDrug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
Locuson, Charles W.
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Luo, Gang
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
M
Ma, Li
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Manevski, Nenad
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
Mauriala, Timo
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
Maxwell, Brad D.
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Meng, W.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Michaud, Josée
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
Mills, Beth Miskimins
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Mkrtchian, Souren
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
Morris, Marilyn E.
- You have accessMonocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 CellsWing Ki Lam, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
Mwinyi, Jessica
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
N
Naud, Judith
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
Nekvindová, Jana
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
O
Obermeier, M.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Okamoto, Kiyoshi
- You have accessExpressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude MiceMichiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu YoshimuraDrug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
Owen, Albert
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
P
Pang, K. Sandy
- You have accessResponse to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Huadong Sun and K. Sandy PangDrug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195
Pedersen, Rasmus Steen
- You have accessNew Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-SundbergDrug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
Pereira, Antonio
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
Picazo, Laura
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Pichette, Vincent
- You have accessDown-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal FailureMélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
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Raghavan, Nirmala
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Remmel, Rory P.
- You have accessGlucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding SitesJin Zhou, Timothy S. Tracy and Rory P. RemmelDrug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712
S
Staskiewicz, Steve J.
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Sugawara, Michiko
- You have accessExpressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude MiceMichiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu YoshimuraDrug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
Sun, Huadong
- You have accessResponse to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Huadong Sun and K. Sandy PangDrug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195
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Tan, Eugene Y.
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Tang, Wei
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
Tolonen, Ari
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
Tracy, Timothy S.
- You have accessGlucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding SitesJin Zhou, Timothy S. Tracy and Rory P. RemmelDrug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712
Turpeinen, Miia
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
U
Uusitalo, Jouko
- You have accessStable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG CellsSébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
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Wagner, John A.
- You have accessMetabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in HumansSanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh KrishnaDrug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
Walters, Rodney R.
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Wang, Lifei
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Washburn, W.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Whaley, J. M.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
White, Julie A.
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Williams, David A.
- You have accessIdentification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of ChloramphenicolMei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. WilliamsDrug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
Wilson, William R.
- You have accessMetabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and HumansYongchuan Gu, Graham J. Atwell and William R. WilsonDrug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973
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Xin, Baomin
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Y
Yang, Jun-Ling
- You have accessComment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng ChenDrug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
Yao, M.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
Yao, Ming
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Yli-Kauhaluoma, Jari
- You have accessGlucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesNenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe FinelDrug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
Yoshimura, Tsutomu
- You have accessExpressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude MiceMichiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu YoshimuraDrug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
Z
Zaya, Matthew J.
- You have accessCurrent Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in DogsBeth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. LocusonDrug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
Zhang, Andy Shiqiang
- You have accessPharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus MonkeysEugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev KumarDrug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
Zhang, Donglu
- You have accessIn Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction StudiesLifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. GrossmanDrug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
Zhang, Wei
- You have accessInvestigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 CellsMalin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. AnderssonDrug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
Zhao, Yuan-Sheng
- You have accessComment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng ChenDrug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
Zheng, Joanna
- You have accessIn Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical PropertiesGang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. HarperDrug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
Zhou, Jin
- You have accessGlucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding SitesJin Zhou, Timothy S. Tracy and Rory P. RemmelDrug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712
Zhu, M.
- You have accessIn Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and HumansM. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. HumphreysDrug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
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