Index by author
December 01, 2012; Volume 40,Issue 12
A
Alt, Jesse
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
Amore, Benny M.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
B
Banfield, Christopher
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Bathala, Mohinder S.
- You have accessPharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in HumansMohinder S. Bathala, Hiroshi Masumoto, Toshihiro Oguma, Ling He, Chris Lowrie and Jeanne MendellDrug Metabolism and Disposition December 2012, 40 (12) 2250-2255; DOI: https://doi.org/10.1124/dmd.112.046888
Beconi, Maria G.
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Boudreaux, Michael D.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Bumpus, Namandjé N.
- You have accessCytochrome P450 3A5 Plays a Prominent Role in the Oxidative Metabolism of the Anti-Human Immunodeficiency Virus Drug MaravirocYanhui Lu, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition December 2012, 40 (12) 2221-2230; DOI: https://doi.org/10.1124/dmd.112.048298
C
Campanale, Kristina
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
Cantin, Louis-David
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
Carella, Consiglia
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Cassidy, Kenneth
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
Chen, Hongming
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
Cheng, Chunru
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
Clifton, Steve
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Colasante, Antonella
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
D
D'Agostino, Jaime
- You have accessBioactivation of the Cancer Chemopreventive Agent Tamoxifen to Quinone Methides by Cytochrome P4502B6 and Identification of the Modified Residue on the ApoproteinChitra Sridar, Jaime D'Agostino and Paul F. HollenbergDrug Metabolism and Disposition December 2012, 40 (12) 2280-2288; DOI: https://doi.org/10.1124/dmd.112.047266
Davis, John A.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Deshmukh, Rahul S.
- You have accessPreferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective MetabolismQingbiao Huang, Rahul S. Deshmukh, Spencer S. Ericksen, Youbin Tu and Grazyna D. SzklarzDrug Metabolism and Disposition December 2012, 40 (12) 2324-2331; DOI: https://doi.org/10.1124/dmd.112.047308
De Tursi, Michele
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Di, Li
- You have accessStatistical Methods for Analysis of Time-Dependent Inhibition of Cytochrome P450 EnzymesPhillip Yates, Heather Eng, Li Di and R. Scott ObachDrug Metabolism and Disposition December 2012, 40 (12) 2289-2296; DOI: https://doi.org/10.1124/dmd.112.047233
Dominguez, Celia
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
E
Emery, Maurice G.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Eng, Heather
- You have accessStatistical Methods for Analysis of Time-Dependent Inhibition of Cytochrome P450 EnzymesPhillip Yates, Heather Eng, Li Di and R. Scott ObachDrug Metabolism and Disposition December 2012, 40 (12) 2289-2296; DOI: https://doi.org/10.1124/dmd.112.047233
Ericksen, Spencer S.
- You have accessPreferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective MetabolismQingbiao Huang, Rahul S. Deshmukh, Spencer S. Ericksen, Youbin Tu and Grazyna D. SzklarzDrug Metabolism and Disposition December 2012, 40 (12) 2324-2331; DOI: https://doi.org/10.1124/dmd.112.047308
F
Foti, Robert S.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
G
Gan, Jinping
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Gong, Jiachang
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Guan, Shuhong
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
Guo, Dean
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
H
Hadden, Chad
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
He, Ling
- You have accessPharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in HumansMohinder S. Bathala, Hiroshi Masumoto, Toshihiro Oguma, Ling He, Chris Lowrie and Jeanne MendellDrug Metabolism and Disposition December 2012, 40 (12) 2250-2255; DOI: https://doi.org/10.1124/dmd.112.046888
Hendrix, Craig W.
- You have accessCytochrome P450 3A5 Plays a Prominent Role in the Oxidative Metabolism of the Anti-Human Immunodeficiency Virus Drug MaravirocYanhui Lu, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition December 2012, 40 (12) 2221-2230; DOI: https://doi.org/10.1124/dmd.112.048298
Hollenberg, Paul F.
- You have accessBioactivation of the Cancer Chemopreventive Agent Tamoxifen to Quinone Methides by Cytochrome P4502B6 and Identification of the Modified Residue on the ApoproteinChitra Sridar, Jaime D'Agostino and Paul F. HollenbergDrug Metabolism and Disposition December 2012, 40 (12) 2280-2288; DOI: https://doi.org/10.1124/dmd.112.047266
- You have accessInhibition of Bupropion Metabolism by Selegiline: Mechanism-Based Inactivation of Human CYP2B6 and Characterization of Glutathione and Peptide AdductsChitra Sridar, Cesar Kenaan and Paul F. HollenbergDrug Metabolism and Disposition December 2012, 40 (12) 2256-2266; DOI: https://doi.org/10.1124/dmd.112.046979
Hoover, Randall
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
Horie, Toru
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Horiguchi, Aya
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Huang, Qingbiao
- You have accessPreferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective MetabolismQingbiao Huang, Rahul S. Deshmukh, Spencer S. Ericksen, Youbin Tu and Grazyna D. SzklarzDrug Metabolism and Disposition December 2012, 40 (12) 2324-2331; DOI: https://doi.org/10.1124/dmd.112.047308
Humphreys, W. Griff
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
I
Iacobelli, Stefano
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Iyer, Ramaswamy A.
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
J
Jay, Michael
- You have accessPharmacokinetics, Bioavailability, Tissue Distribution, Excretion, and Metabolite Identification of Methoxyflavones in Kaempferia parviflora Extract in RatsCatheleeya Mekjaruskul, Michael Jay and Bungorn SripanidkulchaiDrug Metabolism and Disposition December 2012, 40 (12) 2342-2353; DOI: https://doi.org/10.1124/dmd.112.047142
Jemal, Mohammed
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Johnson, Jason
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
K
Kanebratt, Kajsa P.
- You have accessOptimized Experimental Design for the Estimation of Enzyme Kinetic Parameters: An Experimental EvaluationErik Sjögren, Petter Svanberg and Kajsa P. KanebrattDrug Metabolism and Disposition December 2012, 40 (12) 2273-2279; DOI: https://doi.org/10.1124/dmd.112.047373
Kenaan, Cesar
- You have accessInhibition of Bupropion Metabolism by Selegiline: Mechanism-Based Inactivation of Human CYP2B6 and Characterization of Glutathione and Peptide AdductsChitra Sridar, Cesar Kenaan and Paul F. HollenbergDrug Metabolism and Disposition December 2012, 40 (12) 2256-2266; DOI: https://doi.org/10.1124/dmd.112.046979
Kenna, J. Gerry
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
Kitamura, Shigeyuki
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Kobayashi, Taro
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Konno, Yoshihiro
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Kotake, Yaichiro
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
L
Lowrie, Chris
- You have accessPharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in HumansMohinder S. Bathala, Hiroshi Masumoto, Toshihiro Oguma, Ling He, Chris Lowrie and Jeanne MendellDrug Metabolism and Disposition December 2012, 40 (12) 2250-2255; DOI: https://doi.org/10.1124/dmd.112.046888
Lu, Yanhui
- You have accessCytochrome P450 3A5 Plays a Prominent Role in the Oxidative Metabolism of the Anti-Human Immunodeficiency Virus Drug MaravirocYanhui Lu, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition December 2012, 40 (12) 2221-2230; DOI: https://doi.org/10.1124/dmd.112.048298
Lyons, Kathryn
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
M
Massari, Renato
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Masson, Eric
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Masumoto, Hiroshi
- You have accessPharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in HumansMohinder S. Bathala, Hiroshi Masumoto, Toshihiro Oguma, Ling He, Chris Lowrie and Jeanne MendellDrug Metabolism and Disposition December 2012, 40 (12) 2250-2255; DOI: https://doi.org/10.1124/dmd.112.046888
Matsuda, Yoshiki
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Matthews, Kim
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Mead, Tania
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Mekjaruskul, Catheleeya
- You have accessPharmacokinetics, Bioavailability, Tissue Distribution, Excretion, and Metabolite Identification of Methoxyflavones in Kaempferia parviflora Extract in RatsCatheleeya Mekjaruskul, Michael Jay and Bungorn SripanidkulchaiDrug Metabolism and Disposition December 2012, 40 (12) 2342-2353; DOI: https://doi.org/10.1124/dmd.112.047142
Mendell, Jeanne
- You have accessPharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in HumansMohinder S. Bathala, Hiroshi Masumoto, Toshihiro Oguma, Ling He, Chris Lowrie and Jeanne MendellDrug Metabolism and Disposition December 2012, 40 (12) 2250-2255; DOI: https://doi.org/10.1124/dmd.112.046888
Menna, Pierantonio
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Millar, Alan
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
Minotti, Giorgio
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Morisaki, Kunihiko
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Munoz-Sanjuan, Ignacio
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
N
Noeske, Tobias
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
O
O'Connell, Catherine
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Obach, R. Scott
- You have accessStatistical Methods for Analysis of Time-Dependent Inhibition of Cytochrome P450 EnzymesPhillip Yates, Heather Eng, Li Di and R. Scott ObachDrug Metabolism and Disposition December 2012, 40 (12) 2289-2296; DOI: https://doi.org/10.1124/dmd.112.047233
Oguma, Toshihiro
- You have accessPharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in HumansMohinder S. Bathala, Hiroshi Masumoto, Toshihiro Oguma, Ling He, Chris Lowrie and Jeanne MendellDrug Metabolism and Disposition December 2012, 40 (12) 2250-2255; DOI: https://doi.org/10.1124/dmd.112.046888
Ohshita, Hiroki
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Ohta, Shigeru
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
P
Pang, Xiaoyan
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
Patel, Nita
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
Pearson, Josh T.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Prime, Michael
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Prokop, Samantha P.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Pursley, Janice
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
R
Rais, Rana
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
Rehmel, Jessica Fayer
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
Rock, Dan A.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Rojas, Camilo
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
Rudek, Michelle A.
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
S
Salvatorelli, Emanuela
- You have accessPharmacokinetics of Pegylated Liposomal Doxorubicin Administered by Intraoperative Hyperthermic Intraperitoneal Chemotherapy to Patients with Advanced Ovarian Cancer and Peritoneal CarcinomatosisEmanuela Salvatorelli, Michele De Tursi, Pierantonio Menna, Consiglia Carella, Renato Massari, Antonella Colasante, Stefano Iacobelli and Giorgio MinottiDrug Metabolism and Disposition December 2012, 40 (12) 2365-2373; DOI: https://doi.org/10.1124/dmd.112.047480
Sanoh, Seigo
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Satsukawa, Masahiro
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Sjögren, Erik
- You have accessOptimized Experimental Design for the Estimation of Enzyme Kinetic Parameters: An Experimental EvaluationErik Sjögren, Petter Svanberg and Kajsa P. KanebrattDrug Metabolism and Disposition December 2012, 40 (12) 2273-2279; DOI: https://doi.org/10.1124/dmd.112.047373
Slusher, Barbara S.
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
Sridar, Chitra
- You have accessBioactivation of the Cancer Chemopreventive Agent Tamoxifen to Quinone Methides by Cytochrome P4502B6 and Identification of the Modified Residue on the ApoproteinChitra Sridar, Jaime D'Agostino and Paul F. HollenbergDrug Metabolism and Disposition December 2012, 40 (12) 2280-2288; DOI: https://doi.org/10.1124/dmd.112.047266
- You have accessInhibition of Bupropion Metabolism by Selegiline: Mechanism-Based Inactivation of Human CYP2B6 and Characterization of Glutathione and Peptide AdductsChitra Sridar, Cesar Kenaan and Paul F. HollenbergDrug Metabolism and Disposition December 2012, 40 (12) 2256-2266; DOI: https://doi.org/10.1124/dmd.112.046979
Sripanidkulchai, Bungorn
- You have accessPharmacokinetics, Bioavailability, Tissue Distribution, Excretion, and Metabolite Identification of Methoxyflavones in Kaempferia parviflora Extract in RatsCatheleeya Mekjaruskul, Michael Jay and Bungorn SripanidkulchaiDrug Metabolism and Disposition December 2012, 40 (12) 2342-2353; DOI: https://doi.org/10.1124/dmd.112.047142
Stahl, Simone
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
Sugihara, Kazumi
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Svanberg, Petter
- You have accessOptimized Experimental Design for the Estimation of Enzyme Kinetic Parameters: An Experimental EvaluationErik Sjögren, Petter Svanberg and Kajsa P. KanebrattDrug Metabolism and Disposition December 2012, 40 (12) 2273-2279; DOI: https://doi.org/10.1124/dmd.112.047373
Syed, Shariq
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Szklarz, Grazyna D.
- You have accessPreferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective MetabolismQingbiao Huang, Rahul S. Deshmukh, Spencer S. Ericksen, Youbin Tu and Grazyna D. SzklarzDrug Metabolism and Disposition December 2012, 40 (12) 2324-2331; DOI: https://doi.org/10.1124/dmd.112.047308
T
Takimoto, Yu
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Tao, Sijia
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
Tateno, Chise
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Tayama, Yoshitaka
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
Toledo-Sherman, Leticia
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Tsukamoto, Takashi
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
Tu, Youbin
- You have accessPreferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective MetabolismQingbiao Huang, Rahul S. Deshmukh, Spencer S. Ericksen, Youbin Tu and Grazyna D. SzklarzDrug Metabolism and Disposition December 2012, 40 (12) 2324-2331; DOI: https://doi.org/10.1124/dmd.112.047308
U
Uramaru, Naoto
- You have accessPredictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human HepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru OhtaDrug Metabolism and Disposition December 2012, 40 (12) 2267-2272; DOI: https://doi.org/10.1124/dmd.112.047555
W
Wahlstrom, Jan L.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Walker, Clare L.
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
Walter, Daryl
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Warner, Daniel J.
- You have accessMitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural ModificationDaniel J. Warner, Hongming Chen, Louis-David Cantin, J. Gerry Kenna, Simone Stahl, Clare L. Walker and Tobias NoeskeDrug Metabolism and Disposition December 2012, 40 (12) 2332-2341; DOI: https://doi.org/10.1124/dmd.112.047068
Wienkers, Larry C.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Williams, Daphne
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Winkler, Dirk
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Wong, Simon L.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
Wozniak, Krystyna
- You have accessReversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In VivoRana Rais, Randall Hoover, Krystyna Wozniak, Michelle A. Rudek, Takashi Tsukamoto, Jesse Alt, Camilo Rojas and Barbara S. SlusherDrug Metabolism and Disposition December 2012, 40 (12) 2315-2323; DOI: https://doi.org/10.1124/dmd.112.046821
X
Xia, Yuan-Qing
- You have accessMetabolic Chiral Inversion of Brivanib and Its Relevance to Safety and PharmacologyJiachang Gong, Jinping Gan, Eric Masson, Shariq Syed, Yuan-Qing Xia, Daphne Williams, Janice Pursley, Mohammed Jemal, W. Griff Humphreys and Ramaswamy A. IyerDrug Metabolism and Disposition December 2012, 40 (12) 2374-2380; DOI: https://doi.org/10.1124/dmd.112.047340
Y
Yamashita, Shinji
- You have accessAssessment of Intestinal Availability of Various Drugs in the Oral Absorption Process Using Portal Vein-Cannulated RatsYoshiki Matsuda, Yoshihiro Konno, Masahiro Satsukawa, Taro Kobayashi, Yu Takimoto, Kunihiko Morisaki and Shinji YamashitaDrug Metabolism and Disposition December 2012, 40 (12) 2231-2238; DOI: https://doi.org/10.1124/dmd.112.048223
Yang, Min
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
Yates, Dawn
- You have accessMetabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia DominguezDrug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Yates, Phillip
- You have accessStatistical Methods for Analysis of Time-Dependent Inhibition of Cytochrome P450 EnzymesPhillip Yates, Heather Eng, Li Di and R. Scott ObachDrug Metabolism and Disposition December 2012, 40 (12) 2289-2296; DOI: https://doi.org/10.1124/dmd.112.047233
Yi, Ping
- You have accessDisposition and Metabolism of LY2452473, a Selective Androgen Receptor Modulator, in HumansPing Yi, Jessica Fayer Rehmel, Kenneth Cassidy, Chad Hadden, Kristina Campanale, Nita Patel and Jason JohnsonDrug Metabolism and Disposition December 2012, 40 (12) 2354-2364; DOI: https://doi.org/10.1124/dmd.112.047613
Yu, Kate
- You have accessIdentification of Metabolites of Ganoderic Acid D by Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass SpectrometryChunru Cheng, Min Yang, Kate Yu, Shuhong Guan, Sijia Tao, Alan Millar, Xiaoyan Pang and Dean GuoDrug Metabolism and Disposition December 2012, 40 (12) 2307-2314; DOI: https://doi.org/10.1124/dmd.112.047506
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Zalikowski, Julie A.
- You have accessPredicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells ReceptorsRobert S. Foti, Josh T. Pearson, Simon L. Wong, Julie A. Zalikowski, Michael D. Boudreaux, Samantha P. Prokop, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers and Benny M. AmoreDrug Metabolism and Disposition December 2012, 40 (12) 2239-2249; DOI: https://doi.org/10.1124/dmd.112.047928
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