Research ArticleArticle
Metabolism and Pharmacokinetics of JM6 in Mice: JM6 Is Not a Prodrug for Ro-61-8048
Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia Dominguez
Drug Metabolism and Disposition December 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Maria G. Beconi
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Dawn Yates
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Kathryn Lyons
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Kim Matthews
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Steve Clifton
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Tania Mead
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Michael Prime
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Dirk Winkler
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Catherine O'Connell
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Daryl Walter
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Leticia Toledo-Sherman
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Ignacio Munoz-Sanjuan
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
Celia Dominguez
CHDI Management/CHDI Foundation, Princeton, New Jersey (M.G.B., K.L., L.T.-S., I.M.-S., C.D.); BioFocus, Saffron Walden, Essex, United Kingdom (D.Y., K.M., S.C., T.M., C.O.); Evotec (UK) Ltd., Abingdon, United Kingdom (M.P., D.W.); and Evotec AG, Hamburg, Germany (D.W.)
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Research ArticleArticle
METABOLISM AND PHARMACOKINETICS OF JM6 IN MICE
Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia Dominguez
Drug Metabolism and Disposition December 1, 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
Research ArticleArticle
METABOLISM AND PHARMACOKINETICS OF JM6 IN MICE
Maria G. Beconi, Dawn Yates, Kathryn Lyons, Kim Matthews, Steve Clifton, Tania Mead, Michael Prime, Dirk Winkler, Catherine O'Connell, Daryl Walter, Leticia Toledo-Sherman, Ignacio Munoz-Sanjuan and Celia Dominguez
Drug Metabolism and Disposition December 1, 2012, 40 (12) 2297-2306; DOI: https://doi.org/10.1124/dmd.112.046532
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