Research ArticleSpecial Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems
Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and Its Metabolite: Implications for Risk Assessment of Multiple Time-Dependent Inhibitor Systems
Justin D. Lutz, Brooke M. VandenBrink, Katipudi N. Babu, Wendel L. Nelson, Kent L. Kunze and Nina Isoherranen
Drug Metabolism and Disposition December 2013, 41 (12) 2056-2065; DOI: https://doi.org/10.1124/dmd.113.052639
Justin D. Lutz
Department of Pharmaceutics (J.D.L., N.I.) and Department of Medicinal Chemistry (B.M.V., K.N.B., W.L.N., K.L.K.), School of Pharmacy, University of Washington, Seattle, Washington
Brooke M. VandenBrink
Department of Pharmaceutics (J.D.L., N.I.) and Department of Medicinal Chemistry (B.M.V., K.N.B., W.L.N., K.L.K.), School of Pharmacy, University of Washington, Seattle, Washington
Katipudi N. Babu
Department of Pharmaceutics (J.D.L., N.I.) and Department of Medicinal Chemistry (B.M.V., K.N.B., W.L.N., K.L.K.), School of Pharmacy, University of Washington, Seattle, Washington
Wendel L. Nelson
Department of Pharmaceutics (J.D.L., N.I.) and Department of Medicinal Chemistry (B.M.V., K.N.B., W.L.N., K.L.K.), School of Pharmacy, University of Washington, Seattle, Washington
Kent L. Kunze
Department of Pharmaceutics (J.D.L., N.I.) and Department of Medicinal Chemistry (B.M.V., K.N.B., W.L.N., K.L.K.), School of Pharmacy, University of Washington, Seattle, Washington
Nina Isoherranen
Department of Pharmaceutics (J.D.L., N.I.) and Department of Medicinal Chemistry (B.M.V., K.N.B., W.L.N., K.L.K.), School of Pharmacy, University of Washington, Seattle, Washington
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Research ArticleSpecial Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems
Prediction of Fluoxetine Drug-Drug Interactions
Justin D. Lutz, Brooke M. VandenBrink, Katipudi N. Babu, Wendel L. Nelson, Kent L. Kunze and Nina Isoherranen
Drug Metabolism and Disposition December 1, 2013, 41 (12) 2056-2065; DOI: https://doi.org/10.1124/dmd.113.052639
Research ArticleSpecial Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems
Prediction of Fluoxetine Drug-Drug Interactions
Justin D. Lutz, Brooke M. VandenBrink, Katipudi N. Babu, Wendel L. Nelson, Kent L. Kunze and Nina Isoherranen
Drug Metabolism and Disposition December 1, 2013, 41 (12) 2056-2065; DOI: https://doi.org/10.1124/dmd.113.052639
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