Characterization of Transplacental Transfer of Paroxetine in Perfused Human Placenta: Development of a Pharmacokinetic Model to Evaluate Tapered Dosing

Marie Nagai; Hisakazu Ohtani; Hiroki Satoh; Sayo Matsuoka; Satoko Hori; Tomoyuki Fujii; Yuji Taketani; Yasufumi Sawada

doi:10.1124/dmd.113.052332

Research ArticleArticle

Characterization of Transplacental Transfer of Paroxetine in Perfused Human Placenta: Development of a Pharmacokinetic Model to Evaluate Tapered Dosing

Marie Nagai, Hisakazu Ohtani, Hiroki Satoh, Sayo Matsuoka, Satoko Hori, Tomoyuki Fujii, Yuji Taketani and Yasufumi Sawada

Drug Metabolism and Disposition December 2013, 41 (12) 2124-2132; DOI: https://doi.org/10.1124/dmd.113.052332

Marie Nagai

Department of Drug Informatics, Graduate School of Pharmaceutical Sciences, the University of Tokyo (M.N., H.S., S.H., Y.S.); Department of Clinical Pharmacy, Faculty of Pharmacy, Keio University (H.O.); Faculty of Pharmaceutical Sciences, University of Tokyo (S.M.); Interfaculty Initiative in Information Studies, the University of Tokyo (S.H.); Department of Obstetrics and Gynecology, Graduate School of Medicine, the University of Tokyo (T.F., Y.T.), Tokyo, Japan

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Hisakazu Ohtani

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Hiroki Satoh

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Sayo Matsuoka

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Satoko Hori

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Tomoyuki Fujii

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Yuji Taketani

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Yasufumi Sawada

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Drug Metabolism and Disposition

Vol. 41, Issue 12

1 Dec 2013

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