Research ArticleArticle
The Influence of Sex, Ethnicity, and CYP2B6 Genotype on Bupropion Metabolism as an Index of Hepatic CYP2B6 Activity in Humans
Katarina Ilic, Roy L. Hawke, Ranjit K. Thirumaran, Erin G. Schuetz, J. Heyward Hull, Angela D.M. Kashuba, Paul W. Stewart, Celeste M. Lindley and Mei-Ling Chen
Drug Metabolism and Disposition March 2013, 41 (3) 575-581; DOI: https://doi.org/10.1124/dmd.112.048108
Katarina Ilic
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Roy L. Hawke
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Ranjit K. Thirumaran
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Erin G. Schuetz
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
J. Heyward Hull
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Angela D.M. Kashuba
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Paul W. Stewart
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Celeste M. Lindley
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
Mei-Ling Chen
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (K.I., R.L.H., J.H.H., A.D.M.K., C.M.L), Biostatistics Department, School of Public Health (P.W.S.), University of North Carolina, Chapel Hill, North Carolina; University of Belgrade, School of Pharmacy, Belgrade, Serbia (K.I.); Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (R.K.T., E.G.S.); and Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland (M.L.C.)
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Research ArticleArticle
Influences on CYP2B6 Activity Using Bupropion
Katarina Ilic, Roy L. Hawke, Ranjit K. Thirumaran, Erin G. Schuetz, J. Heyward Hull, Angela D.M. Kashuba, Paul W. Stewart, Celeste M. Lindley and Mei-Ling Chen
Drug Metabolism and Disposition March 1, 2013, 41 (3) 575-581; DOI: https://doi.org/10.1124/dmd.112.048108
Research ArticleArticle
Influences on CYP2B6 Activity Using Bupropion
Katarina Ilic, Roy L. Hawke, Ranjit K. Thirumaran, Erin G. Schuetz, J. Heyward Hull, Angela D.M. Kashuba, Paul W. Stewart, Celeste M. Lindley and Mei-Ling Chen
Drug Metabolism and Disposition March 1, 2013, 41 (3) 575-581; DOI: https://doi.org/10.1124/dmd.112.048108
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