Research ArticleArticle
Sorafenib Hepatobiliary Disposition: Mechanisms of Hepatic Uptake and Disposition of Generated Metabolites
Brandon Swift, Noelia Nebot, Jin Kyung Lee, Tianxiang Han, William R. Proctor, Dhiren R. Thakker, Dieter Lang, Martin Radtke, Mark J. Gnoth and Kim L. R. Brouwer
Drug Metabolism and Disposition June 2013, 41 (6) 1179-1186; DOI: https://doi.org/10.1124/dmd.112.048181
Brandon Swift
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Noelia Nebot
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Jin Kyung Lee
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Tianxiang Han
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
William R. Proctor
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Dhiren R. Thakker
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Dieter Lang
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Martin Radtke
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Mark J. Gnoth
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
Kim L. R. Brouwer
Division of Pharmacotherapy and Experimental Therapeutics (B.S., N.N., J.K.L., D.R.T., K.L.R.B.), Division of Molecular Pharmaceutics (T.H., W.R.P.), UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Drug Metabolism and Pharmacokinetics, Bayer Pharma AG, Wuppertal, Germany (D.L., M.R., M.J.G.)
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Research ArticleArticle
Sorafenib Hepatobiliary Disposition
Brandon Swift, Noelia Nebot, Jin Kyung Lee, Tianxiang Han, William R. Proctor, Dhiren R. Thakker, Dieter Lang, Martin Radtke, Mark J. Gnoth and Kim L. R. Brouwer
Drug Metabolism and Disposition June 1, 2013, 41 (6) 1179-1186; DOI: https://doi.org/10.1124/dmd.112.048181
Research ArticleArticle
Sorafenib Hepatobiliary Disposition
Brandon Swift, Noelia Nebot, Jin Kyung Lee, Tianxiang Han, William R. Proctor, Dhiren R. Thakker, Dieter Lang, Martin Radtke, Mark J. Gnoth and Kim L. R. Brouwer
Drug Metabolism and Disposition June 1, 2013, 41 (6) 1179-1186; DOI: https://doi.org/10.1124/dmd.112.048181
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