Index by author
July 01, 2013; Volume 41,Issue 7
A
Abe, Koji
- You have accessIntegrated Approach of In Vivo and In Vitro Evaluation of the Involvement of Hepatic Uptake Organic Anion Transporters in the Drug Disposition in Rats Using Rifampicin as an InhibitorTomoki Imaoka, Tsuyoshi Mikkaichi, Koji Abe, Masakazu Hirouchi, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition July 2013, 41 (7) 1442-1449; DOI: https://doi.org/10.1124/dmd.113.051052
Adane, Eyob D.
- You have accessThe Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In VitroEleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos LeggasDrug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
Arla, Rambabu
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Atwal, Jasvinder K.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
B
Bahar, Fatma Goksin
- You have accessAspirin Hydrolysis in Human and Experimental Animal Plasma and the Effect of Metal Cations on Hydrolase ActivitiesFatma Goksin Bahar and Teruko ImaiDrug Metabolism and Disposition July 2013, 41 (7) 1450-1456; DOI: https://doi.org/10.1124/dmd.113.051805
Balimane, Praveen
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Bednarczyk, Dallas
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Bentz, Joe
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Berry, Loren M.
- You have accessDynamic Modeling of Cytochrome P450 Inhibition In Vitro: Impact of Inhibitor Depletion on IC50 ShiftLoren M. Berry, Zhiyang Zhao and Min-Hwa Jasmine LinDrug Metabolism and Disposition July 2013, 41 (7) 1433-1441; DOI: https://doi.org/10.1124/dmd.113.051508
Brännström, Marie
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Bui, Linh C.
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
Busi, Florent
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
C
Cabral, Shawn
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
Chen, Wansheng
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Chen, Xiaoyan
- You have accessStereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7Jiangbo Du, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition July 2013, 41 (7) 1306-1318; DOI: https://doi.org/10.1124/dmd.113.051235
Cheng, Chen
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Chiba, Masato
- You have accessIon Mobility Spectrometry–Mass Spectrometry Analysis for the Site of Aromatic HydroxylationAtsushi Shimizu and Masato ChibaDrug Metabolism and Disposition July 2013, 41 (7) 1295-1299; DOI: https://doi.org/10.1124/dmd.113.051953
Chien, Jenny Y.
- You have accessOptimization of Drug-Drug Interaction Study Design: Comparison of Minimal Physiologically Based Pharmacokinetic Models on Prediction of CYP3A Inhibition by KetoconazoleBing Han, Jialin Mao, Jenny Y. Chien and Stephen D. HallDrug Metabolism and Disposition July 2013, 41 (7) 1329-1338; DOI: https://doi.org/10.1124/dmd.112.050732
Chu, Xiaoyan
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Chung, Sophie P.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Coleman, JoAnn
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Coraggio, Melis
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
D
Daily, Abigail
- You have accessThe Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In VitroEleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos LeggasDrug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
Dairou, Julien
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
Davis, Connie
- You have accessInhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug InteractionsYoshiyuki Shirasaka, Jennifer E. Sager, Justin D. Lutz, Connie Davis and Nina IsoherranenDrug Metabolism and Disposition July 2013, 41 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.113.051722
Deng, Shibing
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Deshmukh, Gauri
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Di, Peng
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Du, Feifei
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Du, Jiangbo
- You have accessStereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7Jiangbo Du, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition July 2013, 41 (7) 1306-1318; DOI: https://doi.org/10.1124/dmd.113.051235
Dupret, Jean-Marie
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
Duval, Romain
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
E
Ellens, Harma
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Eng, Heather
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
F
Feng, Jin
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Finel, Moshe
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
Forsgard, Malin
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Fukami, Tatsuki
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
Funk, Christoph
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
G
Gao, Xiumei
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Ghosh, Kaushik
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Goosen, Theunis C.
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
Guo, Ailan
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
H
Hall, Stephen D.
- You have accessOptimization of Drug-Drug Interaction Study Design: Comparison of Minimal Physiologically Based Pharmacokinetic Models on Prediction of CYP3A Inhibition by KetoconazoleBing Han, Jialin Mao, Jenny Y. Chien and Stephen D. HallDrug Metabolism and Disposition July 2013, 41 (7) 1329-1338; DOI: https://doi.org/10.1124/dmd.112.050732
Han, Bing
- You have accessOptimization of Drug-Drug Interaction Study Design: Comparison of Minimal Physiologically Based Pharmacokinetic Models on Prediction of CYP3A Inhibition by KetoconazoleBing Han, Jialin Mao, Jenny Y. Chien and Stephen D. HallDrug Metabolism and Disposition July 2013, 41 (7) 1329-1338; DOI: https://doi.org/10.1124/dmd.112.050732
Hanna, Imad
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Herédi-Szabó, Krisztina
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Hillgren, Kate
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Hillgren, Kathleen M.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Hirouchi, Masakazu
- You have accessIntegrated Approach of In Vivo and In Vitro Evaluation of the Involvement of Hepatic Uptake Organic Anion Transporters in the Drug Disposition in Rats Using Rifampicin as an InhibitorTomoki Imaoka, Tsuyoshi Mikkaichi, Koji Abe, Masakazu Hirouchi, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition July 2013, 41 (7) 1442-1449; DOI: https://doi.org/10.1124/dmd.113.051052
Hollnack-Pusch, Evelyn
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Hop, Cornelis E. C. A.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Hu, Zheyi
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Huang, Yuhong
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Hunt, Kevin W.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
I
Imai, Teruko
- You have accessAspirin Hydrolysis in Human and Experimental Animal Plasma and the Effect of Metal Cations on Hydrolase ActivitiesFatma Goksin Bahar and Teruko ImaiDrug Metabolism and Disposition July 2013, 41 (7) 1450-1456; DOI: https://doi.org/10.1124/dmd.113.051805
Imaoka, Tomoki
- You have accessIntegrated Approach of In Vivo and In Vitro Evaluation of the Involvement of Hepatic Uptake Organic Anion Transporters in the Drug Disposition in Rats Using Rifampicin as an InhibitorTomoki Imaoka, Tsuyoshi Mikkaichi, Koji Abe, Masakazu Hirouchi, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition July 2013, 41 (7) 1442-1449; DOI: https://doi.org/10.1124/dmd.113.051052
Isoherranen, Nina
- You have accessInhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug InteractionsYoshiyuki Shirasaka, Jennifer E. Sager, Justin D. Lutz, Connie Davis and Nina IsoherranenDrug Metabolism and Disposition July 2013, 41 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.113.051722
Izukawa, Takeshi
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
Izumi, Takashi
- You have accessIntegrated Approach of In Vivo and In Vitro Evaluation of the Involvement of Hepatic Uptake Organic Anion Transporters in the Drug Disposition in Rats Using Rifampicin as an InhibitorTomoki Imaoka, Tsuyoshi Mikkaichi, Koji Abe, Masakazu Hirouchi, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition July 2013, 41 (7) 1442-1449; DOI: https://doi.org/10.1124/dmd.113.051052
J
Jamei, Masoud
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Jana, Snehasis
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Jiang, Rongrong
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
K
Kalgutkar, Amit S.
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
Katnapally, Prasannakumar
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Kato, Yukiko
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
Kuo, Kuei-Ling
- You have accessThe Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In VitroEleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos LeggasDrug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
L
Lakshmaiah, Basanth
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Lapham, Kimberly
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
Lee, Caroline
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Lee, Caroline A.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Leggas, Markos
- You have accessThe Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In VitroEleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos LeggasDrug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
Li, Chuan
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Li, Jingxian
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Li, LiBin
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Li, Libin
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Lin, Min-Hwa Jasmine
- You have accessDynamic Modeling of Cytochrome P450 Inhibition In Vitro: Impact of Inhibitor Depletion on IC50 ShiftLoren M. Berry, Zhiyang Zhao and Min-Hwa Jasmine LinDrug Metabolism and Disposition July 2013, 41 (7) 1433-1441; DOI: https://doi.org/10.1124/dmd.113.051508
Lin, Xuena
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Liu, Xingrong
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Lutz, Justin D.
- You have accessInhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug InteractionsYoshiyuki Shirasaka, Jennifer E. Sager, Justin D. Lutz, Connie Davis and Nina IsoherranenDrug Metabolism and Disposition July 2013, 41 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.113.051722
Lyssikatos, Joseph
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
M
Manaa, Amine
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
Mandlekar, Sandhya
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Mango, Jason
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Mao, Jialin
- You have accessOptimization of Drug-Drug Interaction Study Design: Comparison of Minimal Physiologically Based Pharmacokinetic Models on Prediction of CYP3A Inhibition by KetoconazoleBing Han, Jialin Mao, Jenny Y. Chien and Stephen D. HallDrug Metabolism and Disposition July 2013, 41 (7) 1329-1338; DOI: https://doi.org/10.1124/dmd.112.050732
Marathe, Punit
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Mason, Andrew K.
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Mazumder Tagore, Debarati
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Mikkaichi, Tsuyoshi
- You have accessIntegrated Approach of In Vivo and In Vitro Evaluation of the Involvement of Hepatic Uptake Organic Anion Transporters in the Drug Disposition in Rats Using Rifampicin as an InhibitorTomoki Imaoka, Tsuyoshi Mikkaichi, Koji Abe, Masakazu Hirouchi, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition July 2013, 41 (7) 1442-1449; DOI: https://doi.org/10.1124/dmd.113.051052
Moscow, Jeffrey A.
- You have accessThe Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In VitroEleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos LeggasDrug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
N
Nakajima, Miki
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
Neuhoff, Sibylle
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Niu, Wei
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
O
O’Connor, Michael
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
O’Connor, Michael P.
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Oda, Shingo
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
Okudaira, Noriko
- You have accessIntegrated Approach of In Vivo and In Vitro Evaluation of the Involvement of Hepatic Uptake Organic Anion Transporters in the Drug Disposition in Rats Using Rifampicin as an InhibitorTomoki Imaoka, Tsuyoshi Mikkaichi, Koji Abe, Masakazu Hirouchi, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition July 2013, 41 (7) 1442-1449; DOI: https://doi.org/10.1124/dmd.113.051052
Orr, Suvi T. M.
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
P
Pahwa, Sonia
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Pak, Anne Y.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Pak, Y. Anne
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Palm, Johan
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Paruchury, Sundeep
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Patel, Aarti
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Peng, Kun
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Perloff, Elke S.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Plise, Emile
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Podila, Lalitha
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Pratap Singh, Sheelendra
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Q
Qian, Xiaofeng
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
R
Ragueneau-Majlessi, Isabelle
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
Rajaraman, Ganesh
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Rasmussen, Birgitte Buur
- You have accessIn Vitro and In Vivo Human Metabolism of Degarelix, a Gonadotropin-Releasing Hormone Receptor BlockerAnders Sonesson and Birgitte Buur RasmussenDrug Metabolism and Disposition July 2013, 41 (7) 1339-1346; DOI: https://doi.org/10.1124/dmd.113.051706
Regal, Kelly
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Reyner, Eric
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Rodrigues-Lima, Fernando
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
Ryder, Tim F.
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
S
Sager, Jennifer E.
- You have accessInhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug InteractionsYoshiyuki Shirasaka, Jennifer E. Sager, Justin D. Lutz, Connie Davis and Nina IsoherranenDrug Metabolism and Disposition July 2013, 41 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.113.051722
Salphati, Laurent
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Sands, Eric
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Scearce-Levie, Kimberly
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Schauer, Stephen P.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Shimizu, Atsushi
- You have accessIon Mobility Spectrometry–Mass Spectrometry Analysis for the Site of Aromatic HydroxylationAtsushi Shimizu and Masato ChibaDrug Metabolism and Disposition July 2013, 41 (7) 1295-1299; DOI: https://doi.org/10.1124/dmd.113.051953
Shin, Young G.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Shirasaka, Yoshiyuki
- You have accessInhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug InteractionsYoshiyuki Shirasaka, Jennifer E. Sager, Justin D. Lutz, Connie Davis and Nina IsoherranenDrug Metabolism and Disposition July 2013, 41 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.113.051722
Singh Gautam, Shashyendra
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Siu, Michael
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Sonesson, Anders
- You have accessIn Vitro and In Vivo Human Metabolism of Degarelix, a Gonadotropin-Releasing Hormone Receptor BlockerAnders Sonesson and Birgitte Buur RasmussenDrug Metabolism and Disposition July 2013, 41 (7) 1339-1346; DOI: https://doi.org/10.1124/dmd.113.051706
Subramanian, Murali
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
T
Tao, Xia
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Taub, Mitchell E.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Taur, Jan-Shiang
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Thomas, Allen A.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Tsakalozou, Eleftheria
- You have accessThe Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In VitroEleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos LeggasDrug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
W
Walker, Gregory S.
- You have accessReactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin ReceptorAmit S. Kalgutkar, Tim F. Ryder, Gregory S. Walker, Suvi T. M. Orr, Shawn Cabral, Theunis C. Goosen, Kimberly Lapham and Heather EngDrug Metabolism and Disposition July 2013, 41 (7) 1375-1388; DOI: https://doi.org/10.1124/dmd.113.051839
Wang, Fengqing
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Watts, Ryan J.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Wei, Hua
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Weitz, Dietmar
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Wildsmith, Kristin R.
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Wong, Harvey
- You have accessMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein ProcessingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J. Watts, Melis Coraggio, Young G. Shin, Kun Peng, Kristin R. Wildsmith, Jasvinder K. Atwal, Jason Mango, Stephen P. Schauer, Kelly Regal, Kevin W. Hunt, Allen A. Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh and Cornelis E. C. A. HopDrug Metabolism and Disposition July 2013, 41 (7) 1319-1328; DOI: https://doi.org/10.1124/dmd.112.050864
Wortelboer, Heleen M.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
X
Xia, Cindy Q.
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Xiao, Guangqing
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Xu, Fang
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Xu, Ximing
- You have accessAcrolein, an α,β-Unsaturated Aldehyde, Irreversibly Inhibits the Acetylation of Aromatic Amine Xenobiotics by Human Arylamine N-Acetyltransferase 1Linh C. Bui, Amine Manaa, Ximing Xu, Romain Duval, Florent Busi, Jean-Marie Dupret, Fernando Rodrigues-Lima and Julien DairouDrug Metabolism and Disposition July 2013, 41 (7) 1300-1305; DOI: https://doi.org/10.1124/dmd.113.052258
Y
Yabut, Jocelyn
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Yamagata, Tetsuo
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Yang, Junling
- You have accessCombinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)Zheyi Hu, Junling Yang, Chen Cheng, Yuhong Huang, Feifei Du, Fengqing Wang, Wei Niu, Fang Xu, Rongrong Jiang, Xiumei Gao and Chuan LiDrug Metabolism and Disposition July 2013, 41 (7) 1457-1469; DOI: https://doi.org/10.1124/dmd.113.051391
Yang, Yingbo
- You have accessEffects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in RatsHua Wei, Xia Tao, Peng Di, Yingbo Yang, Jingxian Li, Xiaofeng Qian, Jin Feng and Wansheng ChenDrug Metabolism and Disposition July 2013, 41 (7) 1398-1403; DOI: https://doi.org/10.1124/dmd.112.050302
Yoganand, Vadari
- You have accessCharacterization of Recombinantly Expressed Rat and Monkey Intestinal Alkaline Phosphatases: In Vitro Studies and In Vivo CorrelationsMurali Subramanian, Sundeep Paruchury, Shashyendra Singh Gautam, Sheelendra Pratap Singh, Rambabu Arla, Sonia Pahwa, Snehasis Jana, Prasannakumar Katnapally, Vadari Yoganand, Basanth Lakshmaiah, Debarati Mazumder Tagore, Kaushik Ghosh, Punit Marathe and Sandhya MandlekarDrug Metabolism and Disposition July 2013, 41 (7) 1425-1432; DOI: https://doi.org/10.1124/dmd.113.051987
Yokoi, Tsuyoshi
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10 in Drug N-Glucuronidation: Substrate Screening and Comparison with UGT1A3 and UGT1A4Yukiko Kato, Takeshi Izukawa, Shingo Oda, Tatsuki Fukami, Moshe Finel, Tsuyoshi Yokoi and Miki NakajimaDrug Metabolism and Disposition July 2013, 41 (7) 1389-1397; DOI: https://doi.org/10.1124/dmd.113.051565
You, Tiangeng
- You have accessStereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7Jiangbo Du, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition July 2013, 41 (7) 1306-1318; DOI: https://doi.org/10.1124/dmd.113.051235
Z
Zhang, Lei
- You have accessApplication of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug InteractionsHarma Ellens, Shibing Deng, JoAnn Coleman, Joe Bentz, Mitchell E. Taub, Isabelle Ragueneau-Majlessi, Sophie P. Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O’Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph Funk, Ailan Guo, Kathleen M. Hillgren, LiBin Li, Anne Y. Pak, Elke S. Perloff, Ganesh Rajaraman, Laurent Salphati, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Tetsuo Yamagata and Caroline A. LeeDrug Metabolism and Disposition July 2013, 41 (7) 1367-1374; DOI: https://doi.org/10.1124/dmd.112.050542
- You have accessVariability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision CriteriaJoe Bentz, Michael P. O’Connor, Dallas Bednarczyk, JoAnn Coleman, Caroline Lee, Johan Palm, Y. Anne Pak, Elke S. Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud Jamei, Xuena Lin, Andrew K. Mason, Sibylle Neuhoff, Aarti Patel, Lalitha Podila, Emile Plise, Ganesh Rajaraman, Laurent Salphati, Eric Sands, Mitchell E. Taub, Jan-Shiang Taur, Dietmar Weitz, Heleen M. Wortelboer, Cindy Q. Xia, Guangqing Xiao, Jocelyn Yabut, Tetsuo Yamagata, Lei Zhang and Harma EllensDrug Metabolism and Disposition July 2013, 41 (7) 1347-1366; DOI: https://doi.org/10.1124/dmd.112.050500
Zhao, Zhiyang
- You have accessDynamic Modeling of Cytochrome P450 Inhibition In Vitro: Impact of Inhibitor Depletion on IC50 ShiftLoren M. Berry, Zhiyang Zhao and Min-Hwa Jasmine LinDrug Metabolism and Disposition July 2013, 41 (7) 1433-1441; DOI: https://doi.org/10.1124/dmd.113.051508
Zhong, Dafang
- You have accessStereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7Jiangbo Du, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition July 2013, 41 (7) 1306-1318; DOI: https://doi.org/10.1124/dmd.113.051235
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