Index by author
September 01, 2013; Volume 41,Issue 9
B
Barbier, Olivier
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
Barbuch, Robert J.
- You have accessThe Relative Contributions of CYP3A4 and CYP3A5 to the Metabolism of VinorelbineAriel R. Topletz, Jennifer B. Dennison, Robert J. Barbuch, Chad E. Hadden, Stephen D. Hall and Jamie L. RenbargerDrug Metabolism and Disposition September 2013, 41 (9) 1651-1661; DOI: https://doi.org/10.1124/dmd.113.051094
Bergström, Helena
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Bernstein, Hilary J.
- You have accessAn Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation StudyHao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein, Kennerly S. Patrick and John S. MarkowitzDrug Metabolism and Disposition September 2013, 41 (9) 1679-1685; DOI: https://doi.org/10.1124/dmd.113.052423
Björkhem-Bergman, Linda
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Brantley, Scott J.
- You have accessA Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A InhibitorsScott J. Brantley, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition September 2013, 41 (9) 1662-1670; DOI: https://doi.org/10.1124/dmd.113.052563
Bridges, Arlene S.
- You have accessIntestinal First-Pass Metabolism by Cytochrome P450 and Not P-Glycoprotein Is the Major Barrier to Amprenavir AbsorptionMatthew B. Dufek, Arlene S. Bridges and Dhiren R. ThakkerDrug Metabolism and Disposition September 2013, 41 (9) 1695-1702; DOI: https://doi.org/10.1124/dmd.113.052191
Bridges, Thomas M.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Brinda, Bryan J.
- You have accessAn Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation StudyHao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein, Kennerly S. Patrick and John S. MarkowitzDrug Metabolism and Disposition September 2013, 41 (9) 1679-1685; DOI: https://doi.org/10.1124/dmd.113.052423
C
Carcache, David
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Caron, Patrick
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
Chakraborty, Abhijit
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Chavin, Kenneth D.
- You have accessAn Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation StudyHao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein, Kennerly S. Patrick and John S. MarkowitzDrug Metabolism and Disposition September 2013, 41 (9) 1679-1685; DOI: https://doi.org/10.1124/dmd.113.052423
Cherrington, Nathan J.
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Cohen-Wolkowiez, Michael
- You have accessThe Role of Human Cytochrome P450 Enzymes in the Formation of 2-Hydroxymetronidazole: CYP2A6 is the High Affinity (Low Km) CatalystRobin E. Pearce, Michael Cohen-Wolkowiez, Mario R. Sampson and Gregory L. KearnsDrug Metabolism and Disposition September 2013, 41 (9) 1686-1694; DOI: https://doi.org/10.1124/dmd.113.052548
Conn, P. Jeffrey
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Cushman, Mark
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
D
Dallas, Shannon
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Daniels, J. Scott
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Dennison, Jennifer B.
- You have accessThe Relative Contributions of CYP3A4 and CYP3A5 to the Metabolism of VinorelbineAriel R. Topletz, Jennifer B. Dennison, Robert J. Barbuch, Chad E. Hadden, Stephen D. Hall and Jamie L. RenbargerDrug Metabolism and Disposition September 2013, 41 (9) 1651-1661; DOI: https://doi.org/10.1124/dmd.113.051094
Dickmann, Leslie J.
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Dufek, Matthew B.
- You have accessIntestinal First-Pass Metabolism by Cytochrome P450 and Not P-Glycoprotein Is the Major Barrier to Amprenavir AbsorptionMatthew B. Dufek, Arlene S. Bridges and Dhiren R. ThakkerDrug Metabolism and Disposition September 2013, 41 (9) 1695-1702; DOI: https://doi.org/10.1124/dmd.113.052191
E
Ekström, Lena
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Eriksson, Mats
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Evers, Raymond
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
F
Fahmi, Odette A.
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Finel, Moshe
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
Flockhart, David A.
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
Flockhart, Peter J.
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
G
Gauthier-Landry, Louis
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
Gogliotti, Rocco D.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Graf, Tyler N.
- You have accessA Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A InhibitorsScott J. Brantley, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition September 2013, 41 (9) 1662-1670; DOI: https://doi.org/10.1124/dmd.113.052563
Gschwind, Hans-Peter
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
H
Hadden, Chad E.
- You have accessThe Relative Contributions of CYP3A4 and CYP3A5 to the Metabolism of VinorelbineAriel R. Topletz, Jennifer B. Dennison, Robert J. Barbuch, Chad E. Hadden, Stephen D. Hall and Jamie L. RenbargerDrug Metabolism and Disposition September 2013, 41 (9) 1651-1661; DOI: https://doi.org/10.1124/dmd.113.051094
Hall, Stephen D.
- You have accessThe Relative Contributions of CYP3A4 and CYP3A5 to the Metabolism of VinorelbineAriel R. Topletz, Jennifer B. Dennison, Robert J. Barbuch, Chad E. Hadden, Stephen D. Hall and Jamie L. RenbargerDrug Metabolism and Disposition September 2013, 41 (9) 1651-1661; DOI: https://doi.org/10.1124/dmd.113.051094
Han, Xu
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
J
Jin, Yi
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Johansson, Maria
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Jones, Carrie K.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
K
Kearns, Gregory L.
- You have accessThe Role of Human Cytochrome P450 Enzymes in the Formation of 2-Hydroxymetronidazole: CYP2A6 is the High Affinity (Low Km) CatalystRobin E. Pearce, Michael Cohen-Wolkowiez, Mario R. Sampson and Gregory L. KearnsDrug Metabolism and Disposition September 2013, 41 (9) 1686-1694; DOI: https://doi.org/10.1124/dmd.113.052548
Kenny, Jane R.
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
King, Roberta S.
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Kittelmann, Matthias
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Krauser, Joel
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Kraynov, Eugenia
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Kunori, Mutsuki
- You have accessCharacterization of Microsomal Glutathione S-Transferases MGST1, MGST2, and MGST3 in Cynomolgus MacaqueYasuhiro Uno, Norie Murayama, Mutsuki Kunori and Hiroshi YamazakiDrug Metabolism and Disposition September 2013, 41 (9) 1621-1625; DOI: https://doi.org/10.1124/dmd.113.052977
L
Lavery, Gareth G.
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
Leuthold, Luc Alexis
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Lindsley, Craig W.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Liu, Jinzhong
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
Lu, Deshun
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
Lu, Wenjie Jessie
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
Lu, Zhenqiang James
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Lv, Wei
- You have accessInhibition of Cytochrome P450 Enzymes by the E- and Z-Isomers of NorendoxifenJinzhong Liu, Peter J. Flockhart, Deshun Lu, Wei Lv, Wenjie Jessie Lu, Xu Han, Mark Cushman and David A. FlockhartDrug Metabolism and Disposition September 2013, 41 (9) 1715-1720; DOI: https://doi.org/10.1124/dmd.113.052506
M
Markowitz, John S.
- You have accessAn Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation StudyHao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein, Kennerly S. Patrick and John S. MarkowitzDrug Metabolism and Disposition September 2013, 41 (9) 1679-1685; DOI: https://doi.org/10.1124/dmd.113.052423
Meyer, Arne
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
More, Vijay
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Morrison, Ryan D.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Murayama, Norie
- You have accessCharacterization of Microsomal Glutathione S-Transferases MGST1, MGST2, and MGST3 in Cynomolgus MacaqueYasuhiro Uno, Norie Murayama, Mutsuki Kunori and Hiroshi YamazakiDrug Metabolism and Disposition September 2013, 41 (9) 1621-1625; DOI: https://doi.org/10.1124/dmd.113.052977
N
Neira, Karissa L.
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Nguyen, Theresa
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Niswender, Colleen M.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Noetzel, Meredith J.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
O
Oberlies, Nicholas H.
- You have accessA Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A InhibitorsScott J. Brantley, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition September 2013, 41 (9) 1662-1670; DOI: https://doi.org/10.1124/dmd.113.052563
Ocwieja, Magdalena
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Odermatt, Alex
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
P
Paine, Mary F.
- You have accessA Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A InhibitorsScott J. Brantley, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition September 2013, 41 (9) 1662-1670; DOI: https://doi.org/10.1124/dmd.113.052563
Parini, Paolo
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Patel, Aarti H.
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Patrick, Kennerly S.
- You have accessAn Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation StudyHao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein, Kennerly S. Patrick and John S. MarkowitzDrug Metabolism and Disposition September 2013, 41 (9) 1679-1685; DOI: https://doi.org/10.1124/dmd.113.052423
Pearce, Robin E.
- You have accessThe Role of Human Cytochrome P450 Enzymes in the Formation of 2-Hydroxymetronidazole: CYP2A6 is the High Affinity (Low Km) CatalystRobin E. Pearce, Michael Cohen-Wolkowiez, Mario R. Sampson and Gregory L. KearnsDrug Metabolism and Disposition September 2013, 41 (9) 1686-1694; DOI: https://doi.org/10.1124/dmd.113.052548
Perreault, Martin
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
R
Rane, Anders
- You have accessAtorvastatin Treatment Induces Uptake and Efflux Transporters in Human LiverLinda Björkhem-Bergman, Helena Bergström, Maria Johansson, Paolo Parini, Mats Eriksson, Anders Rane and Lena EkströmDrug Metabolism and Disposition September 2013, 41 (9) 1610-1615; DOI: https://doi.org/10.1124/dmd.113.051698
Renbarger, Jamie L.
- You have accessThe Relative Contributions of CYP3A4 and CYP3A5 to the Metabolism of VinorelbineAriel R. Topletz, Jennifer B. Dennison, Robert J. Barbuch, Chad E. Hadden, Stephen D. Hall and Jamie L. RenbargerDrug Metabolism and Disposition September 2013, 41 (9) 1651-1661; DOI: https://doi.org/10.1124/dmd.113.051094
Ritzau, Michael
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Rook, Jerri M.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
S
Sampson, Mario R.
- You have accessThe Role of Human Cytochrome P450 Enzymes in the Formation of 2-Hydroxymetronidazole: CYP2A6 is the High Affinity (Low Km) CatalystRobin E. Pearce, Michael Cohen-Wolkowiez, Mario R. Sampson and Gregory L. KearnsDrug Metabolism and Disposition September 2013, 41 (9) 1686-1694; DOI: https://doi.org/10.1124/dmd.113.052548
Schuster, Daniela
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
Slatter, J. Greg
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Slitt, Angela L.
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Stauffer, Shaun R.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Strajhar, Petra
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
Swart, Piet
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
T
Thakker, Dhiren R.
- You have accessIntestinal First-Pass Metabolism by Cytochrome P450 and Not P-Glycoprotein Is the Major Barrier to Amprenavir AbsorptionMatthew B. Dufek, Arlene S. Bridges and Dhiren R. ThakkerDrug Metabolism and Disposition September 2013, 41 (9) 1695-1702; DOI: https://doi.org/10.1124/dmd.113.052191
Topletz, Ariel R.
- You have accessThe Relative Contributions of CYP3A4 and CYP3A5 to the Metabolism of VinorelbineAriel R. Topletz, Jennifer B. Dennison, Robert J. Barbuch, Chad E. Hadden, Stephen D. Hall and Jamie L. RenbargerDrug Metabolism and Disposition September 2013, 41 (9) 1651-1661; DOI: https://doi.org/10.1124/dmd.113.051094
Trottier, Jocelyn
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
U
Ufer, Mike
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Uno, Yasuhiro
- You have accessCharacterization of Microsomal Glutathione S-Transferases MGST1, MGST2, and MGST3 in Cynomolgus MacaqueYasuhiro Uno, Norie Murayama, Mutsuki Kunori and Hiroshi YamazakiDrug Metabolism and Disposition September 2013, 41 (9) 1621-1625; DOI: https://doi.org/10.1124/dmd.113.052977
V
Verreault, Mélanie
- You have accessThe Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid GlucuronidationMartin Perreault, Louis Gauthier-Landry, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Moshe Finel and Olivier BarbierDrug Metabolism and Disposition September 2013, 41 (9) 1616-1620; DOI: https://doi.org/10.1124/dmd.113.052613
Vinson, Paige N.
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Vuorinen, Anna
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
W
Walles, Markus
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Woessner, Ralph
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
Wolf, Thierry
- You have accessMetabolism and Disposition of the Metabotropic Glutamate Receptor 5 Antagonist (mGluR5) Mavoglurant (AFQ056) in Healthy SubjectsMarkus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Joel Krauser, Hans-Peter Gschwind, David Carcache, Matthias Kittelmann, Magdalena Ocwieja, Mike Ufer, Ralph Woessner, Abhijit Chakraborty and Piet SwartDrug Metabolism and Disposition September 2013, 41 (9) 1626-1641; DOI: https://doi.org/10.1124/dmd.112.050716
X
Xiang, Zixiu
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Y
Yalcin, Emine B.
- You have accessDownregulation of Sulfotransferase Expression and Activity in Diseased Human LiversEmine B. Yalcin, Vijay More, Karissa L. Neira, Zhenqiang James Lu, Nathan J. Cherrington, Angela L. Slitt and Roberta S. KingDrug Metabolism and Disposition September 2013, 41 (9) 1642-1650; DOI: https://doi.org/10.1124/dmd.113.050930
Yamazaki, Hiroshi
- You have accessCharacterization of Microsomal Glutathione S-Transferases MGST1, MGST2, and MGST3 in Cynomolgus MacaqueYasuhiro Uno, Norie Murayama, Mutsuki Kunori and Hiroshi YamazakiDrug Metabolism and Disposition September 2013, 41 (9) 1621-1625; DOI: https://doi.org/10.1124/dmd.113.052977
Z
Zhang, Lei
- You have accessCritical Review of Preclinical Approaches to Investigate Cytochrome P450–Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White PaperRaymond Evers, Shannon Dallas, Leslie J. Dickmann, Odette A. Fahmi, Jane R. Kenny, Eugenia Kraynov, Theresa Nguyen, Aarti H. Patel, J. Greg Slatter and Lei ZhangDrug Metabolism and Disposition September 2013, 41 (9) 1598-1609; DOI: https://doi.org/10.1124/dmd.113.052225
Zhou, Ya
- You have accessBiotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent MechanismThomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn and J. Scott DanielsDrug Metabolism and Disposition September 2013, 41 (9) 1703-1714; DOI: https://doi.org/10.1124/dmd.113.052084
Zhu, Hao-Jie
- You have accessAn Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation StudyHao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein, Kennerly S. Patrick and John S. MarkowitzDrug Metabolism and Disposition September 2013, 41 (9) 1679-1685; DOI: https://doi.org/10.1124/dmd.113.052423
Zielinska, Agnieszka E.
- You have accessFormation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex OdermattDrug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
In this issue
Advertisement