Research ArticleArticle
Formation of Threohydrobupropion from Bupropion Is Dependent on 11β-Hydroxysteroid Dehydrogenase 1
Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex Odermatt
Drug Metabolism and Disposition September 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
Arne Meyer
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
Anna Vuorinen
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
Agnieszka E. Zielinska
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
Petra Strajhar
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
Gareth G. Lavery
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
Daniela Schuster
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
Alex Odermatt
Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland (A.M., P.S., A.O.); Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria (A.V., D.S.); and Centre for Endocrinology Diabetes and Metabolism, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (A.E.Z., G.G.L.)
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Research ArticleArticle
Carbonyl Reduction of Bupropion by 11β-HSD1
Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex Odermatt
Drug Metabolism and Disposition September 1, 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
Research ArticleArticle
Carbonyl Reduction of Bupropion by 11β-HSD1
Arne Meyer, Anna Vuorinen, Agnieszka E. Zielinska, Petra Strajhar, Gareth G. Lavery, Daniela Schuster and Alex Odermatt
Drug Metabolism and Disposition September 1, 2013, 41 (9) 1671-1678; DOI: https://doi.org/10.1124/dmd.113.052936
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