Research ArticleSpecial Section on Transporters in Toxicity and Disease
The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
Catherine M. Pastor
Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hôpitaux Universitaires de Genève, Switzerland, and U1149 INSERM-Université Paris Diderot, Sorbonne Paris Cité, Paris, France (C.M.P.); Swiss HPB and Department of Gastroenterology and Hepatology, University Hospital, Zurich, Switzerland (B.M.); and Department of Clinical Pharmacology and Toxicology, University Hospital, Zurich, Switzerland (B.S.)
Beat Müllhaupt
Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hôpitaux Universitaires de Genève, Switzerland, and U1149 INSERM-Université Paris Diderot, Sorbonne Paris Cité, Paris, France (C.M.P.); Swiss HPB and Department of Gastroenterology and Hepatology, University Hospital, Zurich, Switzerland (B.M.); and Department of Clinical Pharmacology and Toxicology, University Hospital, Zurich, Switzerland (B.S.)
Bruno Stieger
Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hôpitaux Universitaires de Genève, Switzerland, and U1149 INSERM-Université Paris Diderot, Sorbonne Paris Cité, Paris, France (C.M.P.); Swiss HPB and Department of Gastroenterology and Hepatology, University Hospital, Zurich, Switzerland (B.M.); and Department of Clinical Pharmacology and Toxicology, University Hospital, Zurich, Switzerland (B.S.)
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In this issue
Research ArticleSpecial Section on Transporters in Toxicity and Disease
Organic Anion Transporters and Liver Imaging Markers
Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
Drug Metabolism and Disposition April 1, 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
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- Article
- Abstract
- Introduction
- Hepatocellular Uptake and Efflux of Organic Anions
- Transport Mechanisms of Organic Anion Transporters
- Role of Imaging in Diagnosing Liver Diseases
- Liver Imaging Related to Hepatic Transporters
- Liver MRI and Hepatobiliary Contrast Agents
- Transport of MR Contrast Agents
- Expression of Transporters and Liver Diseases
- Modifications of Transport Induced by Drug-Drug Interactions
- Future Developments: Hepatic Pharmacokinetics and Hepatic Concentrations
- Outlook
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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