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Research ArticleSpecial Section on Drug Metabolism and the Microbiome—Commentary

Drug Metabolism by the Host and Gut Microbiota: A Partnership or Rivalry?

Hollie I. Swanson
Drug Metabolism and Disposition October 2015, 43 (10) 1499-1504; DOI: https://doi.org/10.1124/dmd.115.065714
Hollie I. Swanson
Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky
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Drug Metabolism and Disposition: 43 (10)
Drug Metabolism and Disposition
Vol. 43, Issue 10
1 Oct 2015
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Research ArticleSpecial Section on Drug Metabolism and the Microbiome—Commentary

Drug Metabolism and the Gut Microbiome

Hollie I. Swanson
Drug Metabolism and Disposition October 1, 2015, 43 (10) 1499-1504; DOI: https://doi.org/10.1124/dmd.115.065714

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Research ArticleSpecial Section on Drug Metabolism and the Microbiome—Commentary

Drug Metabolism and the Gut Microbiome

Hollie I. Swanson
Drug Metabolism and Disposition October 1, 2015, 43 (10) 1499-1504; DOI: https://doi.org/10.1124/dmd.115.065714
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  • Article
    • Abstract
    • Introduction
    • Metabolic Function of the Gut Microbiota
    • Contribution of the Gut Microbiota to Intestinal Immune Homeostasis
    • Role of the Gut Microbiota in Bile Acid Metabolism
    • Gut Microbiota Is an Endocrine Organ and “Second Brain”?
    • Impact of the Gut Microbiota on the Drug-Metabolizing Enzymes, Transporters, and their Regulators
    • Impact of Drugs and Xenobiotics on the Composition and Function of Gut Microorganisms
    • Impact of the Microbiota on the Metabolism and Bioavailability of Phytochemicals
    • Impact of the Gut Microbiome on the Metabolism and Pharmacokinetics of Drugs and Xenobiotics
    • Conclusions
    • Footnotes
    • Abbreviations
    • References
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