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Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423
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