Research ArticleArticle
The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Hanna Mahnke
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Mariana Ballent
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Sven Baumann
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Fernanda Imperiale
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Martin von Bergen
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Carlos Lanusse
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Adrian L. Lifschitz
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Walther Honscha
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
Sandra Halwachs
Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine (H.M., W.H., S.H.), Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology (S.B.), University of Leipzig, Leipzig, Germany; Laboratorio de Farmacología, Centro de Investigacion Veterinaria de Tandil, (CIVETAN, CONICET-CICPBA), Facultad de Cs. Veterinarias, UNCPBA, Tandil, Argentina (M.B., F.I., C.L., A.L.L.); Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany (S.B., M.vB.); Department of Chemistry and Bioscience, Center for Microbial Communities, University of Aalborg, Aalborg, Denmark (M.vB.)
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Research ArticleArticle
Drug Transport across the Bovine Blood-Milk Barrier by ABCG2
Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
Drug Metabolism and Disposition May 1, 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Research ArticleArticle
Drug Transport across the Bovine Blood-Milk Barrier by ABCG2
Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
Drug Metabolism and Disposition May 1, 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
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