Table of Contents

Articles

• Open Access

  Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria

  Flora Scott, Sandra G. Gonzalez Malagon, Brett A. O’Brien, Diede Fennema, Sunil Veeravalli, Clarissa R. Coveney, Ian R. Phillips and Elizabeth A. Shephard

  Drug Metabolism and Disposition September 2017, 45 (9) 982-989; DOI: https://doi.org/10.1124/dmd.117.076612
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  Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic Compounds

  Hsia-lien Lin, Haoming Zhang, Vyvyca J. Walker, Jaime D’Agostino and Paul F. Hollenberg

  Drug Metabolism and Disposition September 2017, 45 (9) 990-999; DOI: https://doi.org/10.1124/dmd.117.075846
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  Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases

  Dustyn A. Barnette, Bryce P. Johnson, Dakota L. Pouncey, Robert Nshimiyimana, Linda P. Desrochers, Thomas E. Goodwin and Grover P. Miller

  Drug Metabolism and Disposition September 2017, 45 (9) 1000-1007; DOI: https://doi.org/10.1124/dmd.117.075929
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  The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates

  Luc R. A. Rougée, Michael A. Mohutsky, David W. Bedwell, Kenneth J. Ruterbories and Stephen D. Hall

  Drug Metabolism and Disposition September 2017, 45 (9) 1008-1018; DOI: https://doi.org/10.1124/dmd.117.076331
• Open Access

  Prediction of Clinically Relevant Herb-Drug Clearance Interactions Using Sandwich-Cultured Human Hepatocytes: Schisandra spp. Case Study

  Jonathan P. Jackson, Kimberly M. Freeman, Weslyn W. Friley, Ashley G. Herman, Christopher B. Black, Kenneth R. Brouwer and Amy L. Roe

  Drug Metabolism and Disposition September 2017, 45 (9) 1019-1026; DOI: https://doi.org/10.1124/dmd.117.075408
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  Evaluation of expression and glycosylation status of UGT1A10 in Supersomes and intestinal epithelial cells with a novel specific UGT1A10 monoclonal antibody

  Shingo Oda, Yukiko Kato, Masahiko Hatakeyama, Atsushi Iwamura, Tatsuki Fukami, Toshiyuki Kume, Tsuyoshi Yokoi and Miki Nakajima

  Drug Metabolism and Disposition September 2017, 45 (9) 1027-1034; DOI: https://doi.org/10.1124/dmd.117.075291
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  Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

  Lei Cao, David J. Greenblatt and Awewura Kwara

  Drug Metabolism and Disposition September 2017, 45 (9) 1035-1043; DOI: https://doi.org/10.1124/dmd.117.076034
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  Age-dependent Protein Abundance of Cytosolic Alcohol and Aldehyde Dehydrogenases in Human Liver

  Deepak Kumar Bhatt, Andrea Gaedigk, Robin E. Pearce, J. Steven Leeder and Bhagwat Prasad

  Drug Metabolism and Disposition September 2017, 45 (9) 1044-1048; DOI: https://doi.org/10.1124/dmd.117.076463