Article Figures & Data
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Data Supplement
- Supplemental Figures -
Supplemental Figure 1 showing FcRn-IgG binding at pH 6.0 via biolayer interferometry (BLI)
Supplemental Figure 2 showing FcRn-IgG binding at pH 7.0 via BLI
Supplemental Figure 3 showing independent FcRn-IgG binding experiments at pH 6.0 via BLI
Supplemental Figure 4 showing independent FcRn-IgG binding experiments at pH 7.0 via BLI
Supplemental Figure 5 showing comparison of FcRn-IgG binding experiments
Supplemental Figure 6 showing unfolding thermograms via differential scanning calorimetry (DSC)
Supplemental Figure 7 showing 3-component, non-2-state fits of IgG DSC data
Supplemental Figure 8 showing calculation of IgG ΔCP of unfolding via DSC
Supplemental Figure 9 showing LASSO analysis with pH 6.0 response
Supplemental Figure 10 showing the effects of allotype and framework on IgG pharmacokinetics
Supplemental Figure 11 showing a comparison of IgG ΔCP of unfolding and GRAVY score
- Supplemental Figures -