Index by author
October 01, 2019; Volume 47,Issue 10
A
Ajjala, Devender Reddy
- You have accessDevelopment and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, Gopinadh Bhyrapuneni, Ramakrishna Nirogi and Albert P. LiDrug Metabolism and Disposition October 2019, 47 (10) 1032-1039; DOI: https://doi.org/10.1124/dmd.119.088237
Aleksunes, Lauren M.
- You have accessIdentification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its MetabolitesRenato J. Scialis, Lauren M. Aleksunes, Iván L. Csanaky, Curtis D. Klaassen and José E. ManautouDrug Metabolism and Disposition October 2019, 47 (10) 1080-1092; DOI: https://doi.org/10.1124/dmd.119.086603
Aluri, Krishna
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Ambudkar, Suresh V.
- You have accessSynthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)Andaleeb Sajid, Natarajan Raju, Sabrina Lusvarghi, Shahrooz Vahedi, Rolf E. Swenson and Suresh V. AmbudkarDrug Metabolism and Disposition October 2019, 47 (10) 1013-1023; DOI: https://doi.org/10.1124/dmd.119.087734
Aral, Jennifer
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
B
Basiri, Babak
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Be, Xuhai
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Berry, Loren
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Bhyrapuneni, Gopinadh
- You have accessDevelopment and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, Gopinadh Bhyrapuneni, Ramakrishna Nirogi and Albert P. LiDrug Metabolism and Disposition October 2019, 47 (10) 1032-1039; DOI: https://doi.org/10.1124/dmd.119.088237
Biswas, Kaustav
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Boucher, Jean-Luc
- You have accessMechanism of H2S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver MicrosomesMartin Dulac, Citra Nagarathinam, Patrick Dansette, Daniel Mansuy and Jean-Luc BoucherDrug Metabolism and Disposition October 2019, 47 (10) 1061-1065; DOI: https://doi.org/10.1124/dmd.119.087205
Brouwer, Kim L.R.
- You have accessOptimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture ConditionsHee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski and Kim L.R. BrouwerDrug Metabolism and Disposition October 2019, 47 (10) 1222-1230; DOI: https://doi.org/10.1124/dmd.119.087676
Bumpus, Namandjé N.
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Burke, Neal S.
- Open AccessCanine Albumin Polymorphisms and Their Impact on Drug Plasma Protein BindingAna P. Costa, Michael H. Court, Neal S. Burke, Zhaohui Zhu, Katrina L. Mealey and Nicolas F. VillarinoDrug Metabolism and Disposition October 2019, 47 (10) 1024-1031; DOI: https://doi.org/10.1124/dmd.119.087304
C
Cass, Robert T.
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Chang, Hsuan-Ping
- You have accessEffect of Size on Solid Tumor Disposition of Protein TherapeuticsZhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo and Dhaval K. ShahDrug Metabolism and Disposition October 2019, 47 (10) 1136-1145; DOI: https://doi.org/10.1124/dmd.119.087809
Chang, Hsueh-Yuan
- You have accessEffect of Size on Solid Tumor Disposition of Protein TherapeuticsZhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo and Dhaval K. ShahDrug Metabolism and Disposition October 2019, 47 (10) 1136-1145; DOI: https://doi.org/10.1124/dmd.119.087809
Chen, Nan
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Chen, Yang
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Cheng, Yuan
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Chong, Saeho
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Chunduru, Prathyusha
- You have accessDevelopment and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, Gopinadh Bhyrapuneni, Ramakrishna Nirogi and Albert P. LiDrug Metabolism and Disposition October 2019, 47 (10) 1032-1039; DOI: https://doi.org/10.1124/dmd.119.088237
Clausen, Valerie
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Conner, Kip
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Costa, Ana P.
- Open AccessCanine Albumin Polymorphisms and Their Impact on Drug Plasma Protein BindingAna P. Costa, Michael H. Court, Neal S. Burke, Zhaohui Zhu, Katrina L. Mealey and Nicolas F. VillarinoDrug Metabolism and Disposition October 2019, 47 (10) 1024-1031; DOI: https://doi.org/10.1124/dmd.119.087304
Court, Michael H.
- Open AccessCanine Albumin Polymorphisms and Their Impact on Drug Plasma Protein BindingAna P. Costa, Michael H. Court, Neal S. Burke, Zhaohui Zhu, Katrina L. Mealey and Nicolas F. VillarinoDrug Metabolism and Disposition October 2019, 47 (10) 1024-1031; DOI: https://doi.org/10.1124/dmd.119.087304
Csanaky, Iván L.
- You have accessIdentification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its MetabolitesRenato J. Scialis, Lauren M. Aleksunes, Iván L. Csanaky, Curtis D. Klaassen and José E. ManautouDrug Metabolism and Disposition October 2019, 47 (10) 1080-1092; DOI: https://doi.org/10.1124/dmd.119.086603
D
Dansette, Patrick
- You have accessMechanism of H2S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver MicrosomesMartin Dulac, Citra Nagarathinam, Patrick Dansette, Daniel Mansuy and Jean-Luc BoucherDrug Metabolism and Disposition October 2019, 47 (10) 1061-1065; DOI: https://doi.org/10.1124/dmd.119.087205
Datta-Mannan, Amita
- Open AccessMechanisms Influencing the Pharmacokinetics and Disposition of Monoclonal Antibodies and PeptidesAmita Datta-MannanDrug Metabolism and Disposition October 2019, 47 (10) 1100-1110; DOI: https://doi.org/10.1124/dmd.119.086488
Deng, Yuzhong
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Dennin, Sean
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Di, Li
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Dragovich, Peter S.
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Dulac, Martin
- You have accessMechanism of H2S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver MicrosomesMartin Dulac, Citra Nagarathinam, Patrick Dansette, Daniel Mansuy and Jean-Luc BoucherDrug Metabolism and Disposition October 2019, 47 (10) 1061-1065; DOI: https://doi.org/10.1124/dmd.119.087205
Dunkoksung, Wilasinee
- You have accessRhinacanthin-C Mediated Herb-Drug Interactions with Drug Transporters and Phase I Drug-Metabolizing EnzymesWilasinee Dunkoksung, Nontima Vardhanabhuti, Pongpun Siripong and Suree JianmongkolDrug Metabolism and Disposition October 2019, 47 (10) 1040-1049; DOI: https://doi.org/10.1124/dmd.118.085647
F
Falsey, James R.
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Foti, Robert S.
- You have accessPharmacokinetic and Drug Metabolism Properties of Novel Therapeutic ModalitiesBrooke M. Rock and Robert S. FotiDrug Metabolism and Disposition October 2019, 47 (10) 1097-1099; DOI: https://doi.org/10.1124/dmd.119.088708
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Fourie-O’Donohue, Aimee
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Fung, Conrad
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
G
Gampa, Gautham
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Gaus, Hans
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
Geng, Donghao
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Glaus, Charles
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Greenlee, Sarah
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
Gu, Yongli
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Guo, Leiming
- You have accessEffect of Size on Solid Tumor Disposition of Protein TherapeuticsZhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo and Dhaval K. ShahDrug Metabolism and Disposition October 2019, 47 (10) 1136-1145; DOI: https://doi.org/10.1124/dmd.119.087809
H
Hao, Yue
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Hariparsad, Niresh
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
Hayashi, Tetsuya
- You have accessThe 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity ReactionsRyuji Kato, Yoshio Ijiri, Tetsuya Hayashi and Jack UetrechtDrug Metabolism and Disposition October 2019, 47 (10) 1093-1096; DOI: https://doi.org/10.1124/dmd.119.087981
Herberich, Brad
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Hickman, Dean
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Holt, Kimberly
- You have accessPrediction of Tissue-Plasma Partition Coefficients Using Microsomal Partitioning: Incorporation into Physiologically based Pharmacokinetic Models and Steady-State Volume of Distribution PredictionsKimberly Holt, Min Ye, Swati Nagar and Ken KorzekwaDrug Metabolism and Disposition October 2019, 47 (10) 1050-1060; DOI: https://doi.org/10.1124/dmd.119.087973
Honkakoski, Paavo
- You have accessOptimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture ConditionsHee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski and Kim L.R. BrouwerDrug Metabolism and Disposition October 2019, 47 (10) 1222-1230; DOI: https://doi.org/10.1124/dmd.119.087676
Hop, Cornelis E.C.A.
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Huang, Liyue
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Huang, Xin
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Humphreys, Sara C.
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Hurh, Eunju
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
I
Ijiri, Yoshio
- You have accessThe 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity ReactionsRyuji Kato, Yoshio Ijiri, Tetsuya Hayashi and Jack UetrechtDrug Metabolism and Disposition October 2019, 47 (10) 1093-1096; DOI: https://doi.org/10.1124/dmd.119.087981
Ikotun, Tayo
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Iqbal, Sajida
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
J
Jiang, Jim
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Jianmongkol, Suree
- You have accessRhinacanthin-C Mediated Herb-Drug Interactions with Drug Transporters and Phase I Drug-Metabolizing EnzymesWilasinee Dunkoksung, Nontima Vardhanabhuti, Pongpun Siripong and Suree JianmongkolDrug Metabolism and Disposition October 2019, 47 (10) 1040-1049; DOI: https://doi.org/10.1124/dmd.118.085647
K
Kang, Hee Eun
- You have accessOptimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture ConditionsHee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski and Kim L.R. BrouwerDrug Metabolism and Disposition October 2019, 47 (10) 1222-1230; DOI: https://doi.org/10.1124/dmd.119.087676
Kato, Ryuji
- You have accessThe 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity ReactionsRyuji Kato, Yoshio Ijiri, Tetsuya Hayashi and Jack UetrechtDrug Metabolism and Disposition October 2019, 47 (10) 1093-1096; DOI: https://doi.org/10.1124/dmd.119.087981
Kenny, Jane R.
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
Kharasch, Evan D.
- You have accessEfavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and StereochemistryPan-Fen Wang, Alicia Neiner and Evan D. KharaschDrug Metabolism and Disposition October 2019, 47 (10) 1195-1205; DOI: https://doi.org/10.1124/dmd.119.086348
Khojasteh, S. Cyrus
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Kim, Joohwan
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Klaassen, Curtis D.
- You have accessIdentification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its MetabolitesRenato J. Scialis, Lauren M. Aleksunes, Iván L. Csanaky, Curtis D. Klaassen and José E. ManautouDrug Metabolism and Disposition October 2019, 47 (10) 1080-1092; DOI: https://doi.org/10.1124/dmd.119.086603
Korzekwa, Ken
- You have accessPrediction of Tissue-Plasma Partition Coefficients Using Microsomal Partitioning: Incorporation into Physiologically based Pharmacokinetic Models and Steady-State Volume of Distribution PredictionsKimberly Holt, Min Ye, Swati Nagar and Ken KorzekwaDrug Metabolism and Disposition October 2019, 47 (10) 1050-1060; DOI: https://doi.org/10.1124/dmd.119.087973
Kozak, Katherine R.
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
L
Lade, Julie M.
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Lai, Yurong
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Li, Albert P.
- You have accessDevelopment and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, Gopinadh Bhyrapuneni, Ramakrishna Nirogi and Albert P. LiDrug Metabolism and Disposition October 2019, 47 (10) 1032-1039; DOI: https://doi.org/10.1124/dmd.119.088237
Li, Hongyan
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Li, Ping
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Li, Yingyi
- You have accessEffect of Size on Solid Tumor Disposition of Protein TherapeuticsZhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo and Dhaval K. ShahDrug Metabolism and Disposition October 2019, 47 (10) 1136-1145; DOI: https://doi.org/10.1124/dmd.119.087809
Li, Zhe
- You have accessEffect of Size on Solid Tumor Disposition of Protein TherapeuticsZhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo and Dhaval K. ShahDrug Metabolism and Disposition October 2019, 47 (10) 1136-1145; DOI: https://doi.org/10.1124/dmd.119.087809
Liang, Limin
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Liu, Li
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Liu, Liling
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Liu, Xiaodong
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Liu, Xingrong
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Liu, Yichin
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Long, Jason
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Lusvarghi, Sabrina
- You have accessSynthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)Andaleeb Sajid, Natarajan Raju, Sabrina Lusvarghi, Shahrooz Vahedi, Rolf E. Swenson and Suresh V. AmbudkarDrug Metabolism and Disposition October 2019, 47 (10) 1013-1023; DOI: https://doi.org/10.1124/dmd.119.087734
M
Ma, Yong
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
Malinen, Melina M.
- You have accessOptimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture ConditionsHee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski and Kim L.R. BrouwerDrug Metabolism and Disposition October 2019, 47 (10) 1222-1230; DOI: https://doi.org/10.1124/dmd.119.087676
Manautou, José E.
- You have accessIdentification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its MetabolitesRenato J. Scialis, Lauren M. Aleksunes, Iván L. Csanaky, Curtis D. Klaassen and José E. ManautouDrug Metabolism and Disposition October 2019, 47 (10) 1080-1092; DOI: https://doi.org/10.1124/dmd.119.086603
Mansuy, Daniel
- You have accessMechanism of H2S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver MicrosomesMartin Dulac, Citra Nagarathinam, Patrick Dansette, Daniel Mansuy and Jean-Luc BoucherDrug Metabolism and Disposition October 2019, 47 (10) 1061-1065; DOI: https://doi.org/10.1124/dmd.119.087205
Matson, John
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
Mealey, Katrina L.
- Open AccessCanine Albumin Polymorphisms and Their Impact on Drug Plasma Protein BindingAna P. Costa, Michael H. Court, Neal S. Burke, Zhaohui Zhu, Katrina L. Mealey and Nicolas F. VillarinoDrug Metabolism and Disposition October 2019, 47 (10) 1024-1031; DOI: https://doi.org/10.1124/dmd.119.087304
Miranda, Les P.
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Mohutsky, Michael
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
Moyer, Bryan
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Murray, Justin
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
N
Nagapudi, Karthik
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Nagar, Swati
- You have accessPrediction of Tissue-Plasma Partition Coefficients Using Microsomal Partitioning: Incorporation into Physiologically based Pharmacokinetic Models and Steady-State Volume of Distribution PredictionsKimberly Holt, Min Ye, Swati Nagar and Ken KorzekwaDrug Metabolism and Disposition October 2019, 47 (10) 1050-1060; DOI: https://doi.org/10.1124/dmd.119.087973
Nagarathinam, Citra
- You have accessMechanism of H2S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver MicrosomesMartin Dulac, Citra Nagarathinam, Patrick Dansette, Daniel Mansuy and Jean-Luc BoucherDrug Metabolism and Disposition October 2019, 47 (10) 1061-1065; DOI: https://doi.org/10.1124/dmd.119.087205
Neiner, Alicia
- You have accessEfavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and StereochemistryPan-Fen Wang, Alicia Neiner and Evan D. KharaschDrug Metabolism and Disposition October 2019, 47 (10) 1195-1205; DOI: https://doi.org/10.1124/dmd.119.086348
Netirojjanakul, Chawita
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Nirogi, Ramakrishna
- You have accessDevelopment and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, Gopinadh Bhyrapuneni, Ramakrishna Nirogi and Albert P. LiDrug Metabolism and Disposition October 2019, 47 (10) 1032-1039; DOI: https://doi.org/10.1124/dmd.119.088237
Nixey, Thomas E.
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
P
Palacharla, Veera Raghava Choudary
- You have accessDevelopment and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, Gopinadh Bhyrapuneni, Ramakrishna Nirogi and Albert P. LiDrug Metabolism and Disposition October 2019, 47 (10) 1032-1039; DOI: https://doi.org/10.1124/dmd.119.088237
Parrott, Neil J.
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
Patilea-Vrana, Gabriela
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Pillow, Thomas H.
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Polson, Andrew
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
Post, Noah
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
R
Raju, Natarajan
- You have accessSynthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)Andaleeb Sajid, Natarajan Raju, Sabrina Lusvarghi, Shahrooz Vahedi, Rolf E. Swenson and Suresh V. AmbudkarDrug Metabolism and Disposition October 2019, 47 (10) 1013-1023; DOI: https://doi.org/10.1124/dmd.119.087734
Ramsden, Diane
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
Robertson, Sarah
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
Rock, Brooke M.
- You have accessPharmacokinetic and Drug Metabolism Properties of Novel Therapeutic ModalitiesBrooke M. Rock and Robert S. FotiDrug Metabolism and Disposition October 2019, 47 (10) 1097-1099; DOI: https://doi.org/10.1124/dmd.119.088708
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Rock, Dan A.
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
S
Sadowsky, Jack D.
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
Sajid, Andaleeb
- You have accessSynthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)Andaleeb Sajid, Natarajan Raju, Sabrina Lusvarghi, Shahrooz Vahedi, Rolf E. Swenson and Suresh V. AmbudkarDrug Metabolism and Disposition October 2019, 47 (10) 1013-1023; DOI: https://doi.org/10.1124/dmd.119.087734
Saran, Chitra
- You have accessOptimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture ConditionsHee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski and Kim L.R. BrouwerDrug Metabolism and Disposition October 2019, 47 (10) 1222-1230; DOI: https://doi.org/10.1124/dmd.119.087676
Scialis, Renato J.
- You have accessIdentification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its MetabolitesRenato J. Scialis, Lauren M. Aleksunes, Iván L. Csanaky, Curtis D. Klaassen and José E. ManautouDrug Metabolism and Disposition October 2019, 47 (10) 1080-1092; DOI: https://doi.org/10.1124/dmd.119.086603
Seneviratne, Herana Kamal
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Shah, Dhaval K.
- You have accessEffect of Size on Solid Tumor Disposition of Protein TherapeuticsZhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo and Dhaval K. ShahDrug Metabolism and Disposition October 2019, 47 (10) 1136-1145; DOI: https://doi.org/10.1124/dmd.119.087809
Sham, Kelvin
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Siripong, Pongpun
- You have accessRhinacanthin-C Mediated Herb-Drug Interactions with Drug Transporters and Phase I Drug-Metabolizing EnzymesWilasinee Dunkoksung, Nontima Vardhanabhuti, Pongpun Siripong and Suree JianmongkolDrug Metabolism and Disposition October 2019, 47 (10) 1040-1049; DOI: https://doi.org/10.1124/dmd.118.085647
Smith, Richard
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Soto, Marcus
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Su, Dian
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
Swenson, Rolf E.
- You have accessSynthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)Andaleeb Sajid, Natarajan Raju, Sabrina Lusvarghi, Shahrooz Vahedi, Rolf E. Swenson and Suresh V. AmbudkarDrug Metabolism and Disposition October 2019, 47 (10) 1013-1023; DOI: https://doi.org/10.1124/dmd.119.087734
T
Tegley, Christopher M.
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Thayer, Mai B.
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
Tran, Linh
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Tweedie, Donald J.
- You have accessPerspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A SubstratesDiane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R. Kenny, Michael Mohutsky, Neil J. Parrott, Sarah Robertson and Donald J. TweedieDrug Metabolism and Disposition October 2019, 47 (10) 1206-1221; DOI: https://doi.org/10.1124/dmd.119.087270
U
Uetrecht, Jack
- You have accessThe 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity ReactionsRyuji Kato, Yoshio Ijiri, Tetsuya Hayashi and Jack UetrechtDrug Metabolism and Disposition October 2019, 47 (10) 1093-1096; DOI: https://doi.org/10.1124/dmd.119.087981
Unadkat, Jashvant D.
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
V
Vahedi, Shahrooz
- You have accessSynthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)Andaleeb Sajid, Natarajan Raju, Sabrina Lusvarghi, Shahrooz Vahedi, Rolf E. Swenson and Suresh V. AmbudkarDrug Metabolism and Disposition October 2019, 47 (10) 1013-1023; DOI: https://doi.org/10.1124/dmd.119.087734
Vardhanabhuti, Nontima
- You have accessRhinacanthin-C Mediated Herb-Drug Interactions with Drug Transporters and Phase I Drug-Metabolizing EnzymesWilasinee Dunkoksung, Nontima Vardhanabhuti, Pongpun Siripong and Suree JianmongkolDrug Metabolism and Disposition October 2019, 47 (10) 1040-1049; DOI: https://doi.org/10.1124/dmd.118.085647
Villarino, Nicolas F.
- Open AccessCanine Albumin Polymorphisms and Their Impact on Drug Plasma Protein BindingAna P. Costa, Michael H. Court, Neal S. Burke, Zhaohui Zhu, Katrina L. Mealey and Nicolas F. VillarinoDrug Metabolism and Disposition October 2019, 47 (10) 1024-1031; DOI: https://doi.org/10.1124/dmd.119.087304
W
Wang, Pan-Fen
- You have accessEfavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and StereochemistryPan-Fen Wang, Alicia Neiner and Evan D. KharaschDrug Metabolism and Disposition October 2019, 47 (10) 1195-1205; DOI: https://doi.org/10.1124/dmd.119.086348
Wang, Wei
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
Wang, Yanfeng
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
Wang, Zhongjian
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Wright, Matthew R.
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Wu, Bin
- You have accessPlasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNASara C. Humphreys, Mai B. Thayer, Julie M. Lade, Bin Wu, Kelvin Sham, Babak Basiri, Yue Hao, Xin Huang, Richard Smith and Brooke M. RockDrug Metabolism and Disposition October 2019, 47 (10) 1174-1182; DOI: https://doi.org/10.1124/dmd.119.086967
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Wu, Jing-Tao
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
X
Xu, Jiong
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Y
Yang, Hanyu
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Ye, Min
- You have accessPrediction of Tissue-Plasma Partition Coefficients Using Microsomal Partitioning: Incorporation into Physiologically based Pharmacokinetic Models and Steady-State Volume of Distribution PredictionsKimberly Holt, Min Ye, Swati Nagar and Ken KorzekwaDrug Metabolism and Disposition October 2019, 47 (10) 1050-1060; DOI: https://doi.org/10.1124/dmd.119.087973
Yin, Lin
- You have accessUse of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical SpeciesRobert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin and Dan A. RockDrug Metabolism and Disposition October 2019, 47 (10) 1111-1121; DOI: https://doi.org/10.1124/dmd.119.087742
Yu, Rosie
- Open AccessMetabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across SpeciesNoah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng WangDrug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
Yu, Shang-Fan
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
Z
Zak, Mark
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Zang, Richard
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Zerler, Brad
- You have accessIn Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and TransportersDiane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna Aluri, Yongli Gu, Sean Dennin, Joohwan Kim and Saeho ChongDrug Metabolism and Disposition October 2019, 47 (10) 1183-1194; DOI: https://doi.org/10.1124/dmd.119.087098
Zhang, Donglu
- You have accessExposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to TissuesDonglu Zhang, Peter S. Dragovich, Shang-Fan Yu, Yong Ma, Thomas H. Pillow, Jack D. Sadowsky, Dian Su, Wei Wang, Andrew Polson, S. Cyrus Khojasteh and Cornelis E.C.A. HopDrug Metabolism and Disposition October 2019, 47 (10) 1146-1155; DOI: https://doi.org/10.1124/dmd.119.087023
- You have accessCatalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug ConjugatesDonglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Thomas H. Pillow, Jack D. Sadowsky, Katherine R. Kozak, Robert T. Cass, Liling Liu, Yuzhong Deng, Yichin Liu, Cornelis E.C.A. Hop and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1156-1163; DOI: https://doi.org/10.1124/dmd.118.086132
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Zhang, Xiangping
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Zhao, Kaijing
- You have accessPrediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and TransportersZhongjian Wang, Hanyu Yang, Jiong Xu, Kaijing Zhao, Yang Chen, Limin Liang, Ping Li, Nan Chen, Donghao Geng, Xiangping Zhang, Xiaodong Liu and Li LiuDrug Metabolism and Disposition October 2019, 47 (10) 1066-1079; DOI: https://doi.org/10.1124/dmd.118.085902
Zhou, Lian
- You have accessDrug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic ModalitiesDonglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus KhojastehDrug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Zhu, Zhaohui
- Open AccessCanine Albumin Polymorphisms and Their Impact on Drug Plasma Protein BindingAna P. Costa, Michael H. Court, Neal S. Burke, Zhaohui Zhu, Katrina L. Mealey and Nicolas F. VillarinoDrug Metabolism and Disposition October 2019, 47 (10) 1024-1031; DOI: https://doi.org/10.1124/dmd.119.087304
In this issue
Advertisement