Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1

Emi Kimoto; Manoli Vourvahis; Renato J. Scialis; Heather Eng; A. David Rodrigues; Manthena V. S. Varma

doi:10.1124/dmd.118.085241

Research ArticleArticle

Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1

Emi Kimoto, Manoli Vourvahis, Renato J. Scialis, Heather Eng, A. David Rodrigues and Manthena V. S. Varma

Drug Metabolism and Disposition May 2019, 47 (5) 493-503; DOI: https://doi.org/10.1124/dmd.118.085241

Emi Kimoto

Pharmacokinetics, Pharmacodynamics and Metabolism, Medicine Design, Pfizer Inc., Groton, Connecticut (E.K., R.J.S., H.E., A.D.R., M.V.S.V.); and Clinical Pharmacology, Pfizer Inc., New York, New York (M.V.)

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Manoli Vourvahis

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Renato J. Scialis

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Heather Eng

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A. David Rodrigues

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Manthena V. S. Varma

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Drug Metabolism and Disposition

Vol. 47, Issue 5

1 May 2019

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