Article Figures & Data
Additional Files
Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Supplemental Methods
Supplemental Figure 1 - Cross-reactivity of anti-CYP2C8 with other CYP450s
Supplemental Figure 2 - Cross-reactivity of anti-CYP1A2 with other CYP450s
Supplemental Figure 3 - CYP1A2-specific metabolic clearance in males across age for a hypothetical compound X derived from in vitro-measured enzyme activity and ontogeny
Supplemental Table 1 - Standard curves used to quantify the amount of both CYP2C8 and CYP1A2 protein in each individual sample
Supplemental Table 2 - Calculation of CYP1A2-mediated metabolic clearance of a hypothetical compound X using IVIVE and the human CYP1A2 expression ontogeny
References
- Supplemental Data -