Research ArticleArticle
Mechanistic in vitro studies indicate that the clinical drug-drug interaction between telithromycin and simvastatin acid is driven by time-dependent inhibition of CYP3A4 with minimal effect on OATP1B1
Robert Elsby, Victoria Hare, Hannah Neal, Samuel Outteridge, Catherine Pearson, Katie Plant, Rachel Upcott Gill, Philip Butler and Robert J Riley
Drug Metabolism and Disposition October 22, 2018, dmd.118.083832; DOI: https://doi.org/10.1124/dmd.118.083832
Robert Elsby
1 Cyprotex Discovery Ltd;
Victoria Hare
1 Cyprotex Discovery Ltd;
Hannah Neal
1 Cyprotex Discovery Ltd;
Samuel Outteridge
1 Cyprotex Discovery Ltd;
Catherine Pearson
1 Cyprotex Discovery Ltd;
Katie Plant
1 Cyprotex Discovery Ltd;
Rachel Upcott Gill
1 Cyprotex Discovery Ltd;
Philip Butler
1 Cyprotex Discovery Ltd;
Robert J Riley
2 Evotec
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Research ArticleArticle
Mechanistic in vitro studies indicate that the clinical drug-drug interaction between telithromycin and simvastatin acid is driven by time-dependent inhibition of CYP3A4 with minimal effect on OATP1B1
Robert Elsby, Victoria Hare, Hannah Neal, Samuel Outteridge, Catherine Pearson, Katie Plant, Rachel Upcott Gill, Philip Butler and Robert J Riley
Drug Metabolism and Disposition October 22, 2018, dmd.118.083832; DOI: https://doi.org/10.1124/dmd.118.083832
Research ArticleArticle
Mechanistic in vitro studies indicate that the clinical drug-drug interaction between telithromycin and simvastatin acid is driven by time-dependent inhibition of CYP3A4 with minimal effect on OATP1B1
Robert Elsby, Victoria Hare, Hannah Neal, Samuel Outteridge, Catherine Pearson, Katie Plant, Rachel Upcott Gill, Philip Butler and Robert J Riley
Drug Metabolism and Disposition October 22, 2018, dmd.118.083832; DOI: https://doi.org/10.1124/dmd.118.083832
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