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Research ArticleShort Communication

Fraction Unbound for Liver Microsome and Hepatocyte Incubations for All Major Species Can Be Approximated Using a Single Species Surrogate

John T Barr, Julie M Lade, Thuy B Tran and Upendra P Dahal
Drug Metabolism and Disposition February 8, 2019, dmd.118.085936; DOI: https://doi.org/10.1124/dmd.118.085936
John T Barr
Amgen
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Julie M Lade
Amgen
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Thuy B Tran
Amgen
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Upendra P Dahal
Amgen
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  • For correspondence: udahal@amgen.com
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      Supplementary Table 1. Tuning parameter for tandem mass spectrometry analysis of 36 drugs evaluated.

      Supplementary Figure 1. Stratification of compounds based on chemical class.

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Drug Metabolism and Disposition: 47 (3)
Drug Metabolism and Disposition
Vol. 47, Issue 3
1 Mar 2019
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Research ArticleShort Communication

Fraction Unbound for Liver Microsome and Hepatocyte Incubations for All Major Species Can Be Approximated Using a Single Species Surrogate

John T Barr, Julie M Lade, Thuy B Tran and Upendra P Dahal
Drug Metabolism and Disposition February 8, 2019, dmd.118.085936; DOI: https://doi.org/10.1124/dmd.118.085936

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Research ArticleShort Communication

Fraction Unbound for Liver Microsome and Hepatocyte Incubations for All Major Species Can Be Approximated Using a Single Species Surrogate

John T Barr, Julie M Lade, Thuy B Tran and Upendra P Dahal
Drug Metabolism and Disposition February 8, 2019, dmd.118.085936; DOI: https://doi.org/10.1124/dmd.118.085936
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