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Computational prediction of the site(s) of metabolism (SOM) and binding modes of protein kinase inhibitors metabolised by CYP3A4
Pramod C. Nair, Ross A. McKinnon and John O. Miners

Drug Metabolism and Disposition March 22, 2019, dmd.118.085167; DOI: https://doi.org/10.1124/dmd.118.085167
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Developmental Expression of the Cytosolic Sulfotransferases in Human Liver
Sarah Dubaisi, Joseph A Caruso, Roger Gaedigk, Carrie A. Vyhlidal, Philip C. Smith, Ronald N. Hines, Thomas A. Kocarek and Melissa Runge-Morris

Drug Metabolism and Disposition March 18, 2019, dmd.119.086363; DOI: https://doi.org/10.1124/dmd.119.086363
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Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8
Helinä Kahma, Anne M. Filppula, Terhi Launiainen, Jenni Viinamäki, Mikko Neuvonen, Eric A. Evangelista, Rheem A. Totah and Janne T. Backman

Drug Metabolism and Disposition April 2019, 47 (4) 436-443; DOI: https://doi.org/10.1124/dmd.118.085498
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Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19
Sandhya Devarajan, Irene Moon, Ming-Fen Ho, Nicholas B. Larson, Drew R. Neavin, Ann M. Moyer, John L. Black, Suzette J. Bielinski, Steven E. Scherer, Liewei Wang, Richard M. Weinshilboum and Joel M. Reid

Drug Metabolism and Disposition April 2019, 47 (4) 425-435; DOI: https://doi.org/10.1124/dmd.118.084269
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Correction to “Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children”
Drug Metabolism and Disposition April 2019, 47 (4) 424; DOI: https://doi.org/10.1124/dmd.117.072256err
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Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1
Emi Kimoto, Manoli Vourvahis, Renato J. Scialis, Heather Eng, A. David Rodrigues and Manthena V. S. Varma

Drug Metabolism and Disposition March 12, 2019, dmd.118.085241; DOI: https://doi.org/10.1124/dmd.118.085241
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A novel depurination methodology to assess DNA alkylation of chloro bis-seco-cyclopropylbenzoindoles (CBIs) allowed for comparison of minor groove reactivity
Shuai Wang, Buyun Chen, Peter Dragovich, Thomas Pillow, Leanna Staben, Jun Guo, Dian Su, Chenghong Zhang, Sudheer Bobba, Yong Ma, Jianshuang Wang, Dewakar Sangaraju, BinQing Wei, Gail Lewis Phillips, Cyrus Khojasteh and Donglu Zhang

Drug Metabolism and Disposition March 11, 2019, dmd.118.085209; DOI: https://doi.org/10.1124/dmd.118.085209
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Role of ABCG2 in secretion into milk of the anti-inflammatory flunixin and its main metabolite: in vitro-in vivo correlation in mice and cows
Dafne Garcia-Mateos, Alba Maria Garcia-Lino, Indira Alvarez-Fernandez, Esther Blanco-Paniagua, Alvaro de la Fuente, Ana I Alvarez and Gracia Merino

Drug Metabolism and Disposition March 11, 2019, dmd.118.085506; DOI: https://doi.org/10.1124/dmd.118.085506
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Hepatocyte Concentrations of Imaging Compounds Associated with Transporter Inhibition: Evidence in Perfused Rat Livers
Pierre Bonnaventure, Fabien Cusin and Catherine M. Pastor

Drug Metabolism and Disposition April 2019, 47 (4) 412-418; DOI: https://doi.org/10.1124/dmd.118.084624
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Brain Distribution of a Panel of Epidermal Growth Factor Receptor Inhibitors Using Cassette Dosing in Wild-Type and Abcb1/Abcg2-Deficient Mice
Minjee Kim, Janice K. Laramy, Afroz S. Mohammad, Surabhi Talele, James Fisher, Jann N. Sarkaria and William F. Elmquist

Drug Metabolism and Disposition April 2019, 47 (4) 393-404; DOI: https://doi.org/10.1124/dmd.118.084210

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