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Mechanism of H2S formation from the metabolism of anetholedithiolethione and anetholedithiolone by rat liver microsomes
Martin Dulac, Citra Nagarathinan, Patrick M Dansette, Daniel Mansuy and Jean-Luc Boucher

Drug Metabolism and Disposition June 18, 2019, dmd.119.087205; DOI: https://doi.org/10.1124/dmd.119.087205
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Regulatory Recommendations for Calculating the Unbound Maximum Hepatic Inlet Concentration: A Complicated Story with a Surprising and Happy Ending
Andrew Parkinson

Drug Metabolism and Disposition July 2019, 47 (7) 779-784; DOI: https://doi.org/10.1124/dmd.119.086496
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Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
Maciej J Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S Taskar, Jane Huang, Yong Huang and Elizabeth H Romach

Drug Metabolism and Disposition June 18, 2019, dmd.119.087635; DOI: https://doi.org/10.1124/dmd.119.087635
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A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters
Péter Tátrai, Patrick Schweigler, Birk Poller, Norbert Domange, Roelof de Wilde, Imad Hanna, Zsuzsanna Gáborik and Felix Huth

Drug Metabolism and Disposition July 2019, 47 (7) 768-778; DOI: https://doi.org/10.1124/dmd.118.085993
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Potential for Underestimation of d-Methylphenidate Bioavailability Using Chiral Derivatization/Gas Chromatography
Kennerly S. Patrick and Wendy Rodriguez

Drug Metabolism and Disposition July 2019, 47 (7) 764-767; DOI: https://doi.org/10.1124/dmd.119.087189
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Structure guided in-vitro to in-vivo pharmacokinetic optimization of propargyl-linked antifolates
Michael N Lombardo, Narendran G-Dayanandan, Santosh Keshipeddy, Wangda Zhou, Debjani Si, Stephanie M Reeve, Jeremy Alverson, Patrick Barney, Larissa Walker, John Hoody, Nigel Priestley, R. Scott Obach and Dennis L Wright

Drug Metabolism and Disposition June 14, 2019, dmd.119.086504; DOI: https://doi.org/10.1124/dmd.119.086504
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The enhancement of subcutaneous first-pass metabolism causes non-linear pharmacokinetics of TAK-448 after a single subcutaneous administration to rats
Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet

Drug Metabolism and Disposition June 14, 2019, dmd.119.087148; DOI: https://doi.org/10.1124/dmd.119.087148
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PBDEs and Gut Microbiome Modulate Metabolic Syndrome-Related Aqueous Metabolites in Mice
David K Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui

Drug Metabolism and Disposition June 12, 2019, dmd.119.086538; DOI: https://doi.org/10.1124/dmd.119.086538
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Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability
Xiaoyu Fan, Hongmin Li, Xinxin Ding and Qing-Yu Zhang

Drug Metabolism and Disposition July 2019, 47 (7) 756-763; DOI: https://doi.org/10.1124/dmd.119.086678
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Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F Ryder, Lorenzo Leggio and Fatemeh Akhlaghi

Drug Metabolism and Disposition June 10, 2019, dmd.119.087015; DOI: https://doi.org/10.1124/dmd.119.087015

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