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Selection of Priority Natural Products for Evaluation as Potential Precipitants of Natural Product–Drug Interactions: A NaPDI Center Recommended Approach
Emily J. Johnson, Vanessa González-Peréz, Dan-Dan Tian, Yvonne S. Lin, Jashvant D. Unadkat, Allan E. Rettie, Danny D. Shen, Jeannine S. McCune and Mary F. Paine

Drug Metabolism and Disposition July 2018, 46 (7) 1046-1052; DOI: https://doi.org/10.1124/dmd.118.081273
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Structure-Activity Relationships of the Main Bioactive Constituents of Euodia rutaecarpa on Aryl Hydrocarbon Receptor Activation and Associated Bile Acid Homeostasis
Youbo Zhang, Tingting Yan, Dongxue Sun, Cen Xie, Yiran Zheng, Lei Zhang, Tomoki Yagai, Kristopher W. Krausz, William H. Bisson, Xiuwei Yang and Frank J. Gonzalez

Drug Metabolism and Disposition July 2018, 46 (7) 1030-1040; DOI: https://doi.org/10.1124/dmd.117.080176
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Recommended Approaches for Pharmacokinetic Natural Product-Drug Interaction Research: a NaPDI Center Commentary
Mary F. Paine, Danny D. Shen and Jeannine S. McCune

Drug Metabolism and Disposition July 2018, 46 (7) 1041-1045; DOI: https://doi.org/10.1124/dmd.117.079962
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An investigation into the prediction of the plasma concentration-time profile and its inter-individual variability for a range of flavin-containing monooxygenase substrates using a mechanistic physiologically based pharmacokinetic modelling approach
Venkatesh Pilla Reddy, Barry C Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi Li

Drug Metabolism and Disposition June 12, 2018, dmd.118.080648; DOI: https://doi.org/10.1124/dmd.118.080648
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Transport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Oatps
Kazuya Ishida, Mohammed Ullah, Beata Toth, Viktoria Juhasz and Jashvant D Unadkat

Drug Metabolism and Disposition June 11, 2018, dmd.118.080770; DOI: https://doi.org/10.1124/dmd.118.080770
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Three Faces of Mercaptopurine Cytotoxicity in vitro: Methylation, Nucleotide Homeostasis and Deoxythioguanosine in DNA
Sally A Coulthard, Sarah McGarrity, Kalvin Sahota, Philip Berry and Christopher P.F. Redfern

Drug Metabolism and Disposition June 8, 2018, dmd.118.081844; DOI: https://doi.org/10.1124/dmd.118.081844
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Consequences of Phenytoin Exposure on Hepatic Cytochrome P450 Expression during Postnatal Liver Maturation in Mice
Stephanie C. Piekos, Liming Chen, Pengcheng Wang, Jian Shi, Sharon Yaqoob, Hao-Jie Zhu, Xiaochao Ma and Xiao-bo Zhong

Drug Metabolism and Disposition June 8, 2018, dmd.118.080861; DOI: https://doi.org/10.1124/dmd.118.080861
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S-Enantiomer of 19-Hydroxyeicosatetraenoic Acid Preferentially Protects Against Angiotensin II-Induced Cardiac Hypertrophy
Sherif M. Shoieb and Ayman O.S. El-Kadi

Drug Metabolism and Disposition June 7, 2018, dmd.118.082073; DOI: https://doi.org/10.1124/dmd.118.082073
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Development and Characterisation of a Human Hepatocyte Low Intrinsic Clearance Assay for Use in Drug Discovery
Paul Lancett, Beth Williamson, Patrick Barton and Rob J Riley

Drug Metabolism and Disposition June 7, 2018, dmd.118.081596; DOI: https://doi.org/10.1124/dmd.118.081596
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Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus Monkey
Rachel E Kosa, Sarah Lazzaro, Yi-an Bi, Brendan Tierney, Dana Gates, Sweta Modi, Chester Costales, A. David Rodrigues, Larry M Tremaine and Manthena V Varma

Drug Metabolism and Disposition June 7, 2018, dmd.118.081794; DOI: https://doi.org/10.1124/dmd.118.081794

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