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Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells
John Cerrone, Choon-myung Lee, Tian Mi and Edward T. Morgan

Drug Metabolism and Disposition July 2020, 48 (7) 544-552; DOI: https://doi.org/10.1124/dmd.119.089961
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Are There Any Experimental Perfusion Data that Preferentially Support the Dispersion and Parallel-Tube Models over the Well-Stirred Model of Organ Elimination?
Jasleen K. Sodhi, Hong-Jaan Wang and Leslie Z. Benet

Drug Metabolism and Disposition July 2020, 48 (7) 537-543; DOI: https://doi.org/10.1124/dmd.120.090530
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Concentration Dependence of the Unbound Partition Coefficient Kp_uu and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors
Cornelius Trünkle, Christian Lechner, Daniel Korr, Léa Bouché, Naomi Barak, Amaury Fernández-Montalván, Roderich D Süssmuth and Andreas Reichel

Drug Metabolism and Disposition July 2020, 48 (7) 553-562; DOI: https://doi.org/10.1124/dmd.120.090563
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Excretion, Mass balance and Metabolism of [¹⁴C] LY3202626 in Humans: An interplay of microbial reduction, reabsorption, and AO oxidation that leads to an extended excretion profile
Kishore Kumar Katyayan, Ping Yi, Scott A Monk and Kenneth C. Cassidy

Drug Metabolism and Disposition June 4, 2020, DMD-AR-2020-000009; DOI: https://doi.org/10.1124/dmd.120.000009
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Impact of Microbiome on Hepatic Metabolizing Enzymes and Transporters in Mice during Pregnancy
Lyrialle W. Han, Lu Wang, Yuanyuan Shi, Joseph L Dempsey, Olesya V Pershutkina, Moumita Dutta, Theo K Bammler, Julia Yue Cui and Qingcheng Mao

Drug Metabolism and Disposition June 4, 2020, DMD-AR-2020-000039; DOI: https://doi.org/10.1124/dmd.120.000039
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Urinary Bile Acids Profile of Cesarean Sectioned Newborns is Characterized by Oxidative Metabolism of Primary Bile Acids: Limited Roles of Fetal-specific CYP3A7 in Cholate Oxidations.
Wen-Xia Wang, Li Chen, Guo-Yu Wang, Jin-Ling Zhang, Xianwen Tan, Qiu-Hong Lin, Yu-Jie Chen, Jian Zhang, Ping-Ping Zhu, Jia Miao, Mingming Su, Changxiao Liu, Wei Jia and Ke Lan

Drug Metabolism and Disposition June 4, 2020, DMD-AR-2020-000011; DOI: https://doi.org/10.1124/dmd.120.000011
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OATP1B3 expression and function is modulated by co-expression with OCT1, OATP1B1, and NTCP
Yuchen Zhang, Melissa Ruggiero and Bruno Hagenbuch

Drug Metabolism and Disposition June 1, 2020, dmd.119.089847; DOI: https://doi.org/10.1124/dmd.119.089847
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NADPH-Independent Inactivation of CYP2B6 and NADPH-dependent Inactivation of CYP3A4/5 by Pyrrolobenzodiazepine Dimer (PBD) and Potential Implication for Assessing Covalent Modulators for Time-dependent Inhibition
Mika Kosaka, Donglu Zhang, Simon Wong and Zhengyin Yan

Drug Metabolism and Disposition June 1, 2020, dmd.120.090878; DOI: https://doi.org/10.1124/dmd.120.090878
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Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for OATP Inhibition
Xiaomei Gu, Lifei Wang, Jinping Gan, R. Marcus Fancher, Yuan Tian, Yang Hong, Yurong Lai, Michael Sinz and Hong Shen

Drug Metabolism and Disposition June 1, 2020, dmd.120.090670; DOI: https://doi.org/10.1124/dmd.120.090670
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HUMAN LIVER MICROSOMES IMMOBILIZED ON MAGNETIZABLE BEADS: AN IMPROVED APPROACH TO STUDYING IN VITRO DRUG METABOLISM
Alexander Matthew Horspool, Ting Wang, Young-Sun Scaringella, Mitchell Ethan Taub and Tom Sze-Yin Chan

Drug Metabolism and Disposition May 30, 2020, dmd.120.090696; DOI: https://doi.org/10.1124/dmd.120.090696

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