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Drug Metabolism & Disposition

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Latest Articles

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    UDP-glycosyltransferase 3A (UGT3A) metabolism of polycyclic aromatic hydrocarbons: potential importance in aerodigestive tract tissues
    Ana G. Vergara, Christy J.W. Watson, Gang Chen and Philip Lazarus
    Drug Metabolism and Disposition December 13, 2019, dmd.119.089284; DOI: https://doi.org/10.1124/dmd.119.089284
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    Identification and characterization of a new carboxylesterase 2 isozyme, mfCES2C, in the small intestine of cynomolgus monkeys
    Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
    Drug Metabolism and Disposition December 13, 2019, dmd.119.089011; DOI: https://doi.org/10.1124/dmd.119.089011
  • Assessment and Confirmation of Species Difference in Nonlinear Pharmacokinetics of Atipamezole with Physiologically Based Pharmacokinetic Modeling
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    Assessment and Confirmation of Species Difference in Nonlinear Pharmacokinetics of Atipamezole with Physiologically Based Pharmacokinetic Modeling
    Zheng Li, You Gao, Chunmiao Yang, Yanan Xiang, Wenpeng Zhang, Tianhong Zhang, Ruibin Su, Chuang Lu and Xiaomei Zhuang
    Drug Metabolism and Disposition January 2020, 48 (1) 41-51; DOI: https://doi.org/10.1124/dmd.119.089151
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    Comparative Proteomics Analysis of Human Liver Microsomes and S9 Fractions
    Xinwen Wang, Bing He, Jian Shi, Qian Li and Hao-Jie Zhu
    Drug Metabolism and Disposition January 2020, 48 (1) 31-40; DOI: https://doi.org/10.1124/dmd.119.089235
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    Numerical Analysis of Time-Dependent Inhibition by MDMA
    John T. Rodgers and Jeffrey P. Jones
    Drug Metabolism and Disposition January 2020, 48 (1) 1-7; DOI: https://doi.org/10.1124/dmd.119.089268
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    NRF2-Independent Regulation of Intestinal Constitutive Androstane Receptor by the Pro-Oxidants Cadmium and Isothiocyanate in hUGT1 Mice
    Miles Paszek and Robert H. Tukey
    Drug Metabolism and Disposition January 2020, 48 (1) 25-30; DOI: https://doi.org/10.1124/dmd.119.089508
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    Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma
    Christine M. Bowman, Eugene Chen, Liuxi Chen, Yi-Chen Chen, Xiaorong Liang, Matthew Wright, Yuan Chen and Jialin Mao
    Drug Metabolism and Disposition January 2020, 48 (1) 18-24; DOI: https://doi.org/10.1124/dmd.119.088948
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    A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity
    Veronica Krogstad, Alexandra Peric, Ida Robertsen, Marianne K. Kringen, Christine Wegler, Philip Carlo Angeles, Jøran Hjelmesæth, Cecilia Karlsson, Shalini Andersson, Per Artursson, Anders Åsberg, Tommy B. Andersson and Hege Christensen
    Drug Metabolism and Disposition January 2020, 48 (1) 8-17; DOI: https://doi.org/10.1124/dmd.119.087940
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    Abundant expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1 and xCT transporters in blood-arachnoid barrier of pig, and polarized localizations at CSF- and blood-facing plasma membranes
    Yasuo Uchida, Ryohei Goto, Hina Takeuchi, Magdalena Łuczak, Takuya Usui, Masanori Tachikawa and Tetsuya Terasaki
    Drug Metabolism and Disposition November 26, 2019, dmd.119.089516; DOI: https://doi.org/10.1124/dmd.119.089516
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    Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-mediated Uptake
    Bridget L. Morse, Anil Kolur, Loyd R Hudson, Andrew T. Hogan, Lisa Hong Chen, Ryan M. Brackman, Geri A. Sawada, John K. Fallon, Philip C. Smith and Kathleen M. Hillgren
    Drug Metabolism and Disposition November 26, 2019, dmd.119.088781; DOI: https://doi.org/10.1124/dmd.119.088781

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