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Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman

Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523
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Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice
Lei Li, Xiaochen Bao, Qing-Yu Zhang, Masahiko Negishi and Xinxin Ding

Drug Metabolism and Disposition August 2017, 45 (8) 977-981; DOI: https://doi.org/10.1124/dmd.117.076406
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Creation and Preliminary Characterization of Pregnane X Receptor and Constitutive Androstane Receptor Knockout Rats
Kevin P Forbes, Evguenia Kouranova, Daniel Tinker, Karen Janowski, Doug Cortner, Aaron McCoy and Xiaoxia Cui

Drug Metabolism and Disposition July 17, 2017, dmd.117.075788; DOI: https://doi.org/10.1124/dmd.117.075788
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Oxetane Substrates of Human Microsomal Epoxide Hydrolase
Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes

Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489
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CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni

Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307
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Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic Compounds
Hsia-lien Lin, Haoming Zhang, Vyvyca J. Walker, Jaime D'Agostino and Paul F. Hollenberg

Drug Metabolism and Disposition July 11, 2017, dmd.117.075846; DOI: https://doi.org/10.1124/dmd.117.075846
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Evaluation of expression and glycosylation status of UGT1A10 in Supersomes and intestinal epithelial cells with a novel specific UGT1A10 monoclonal antibody
Shingo Oda, Yukiko Kato, Masahiko Hatakeyama, Atsushi Iwamura, Tatsuki Fukami, Toshiyuki Kume, Tsuyoshi Yokoi and Miki Nakajima

Drug Metabolism and Disposition July 11, 2017, dmd.117.075291; DOI: https://doi.org/10.1124/dmd.117.075291
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Prediction of Clinically Relevant Herb-Drug Clearance Interactions Using a Whole Cell Approach: Schisandra sphenanthera case study
Jonathan P Jackson, Kimberly M Freeman, Weslyn W Friley, Ashley G Herman, Christopher B Black, Kenneth R Brouwer and Amy L Roe

Drug Metabolism and Disposition July 11, 2017, dmd.117.075408; DOI: https://doi.org/10.1124/dmd.117.075408
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Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki

Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630
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Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the model for passive placental permeability drugs
Zufei Zhang and Jashvant D. Unadkat

Drug Metabolism and Disposition August 2017, 45 (8) 939-946; DOI: https://doi.org/10.1124/dmd.116.073957

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