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Numerical Analysis of Time-Dependent Inhibition by MDMA
John T. Rodgers and Jeffrey P. Jones

Drug Metabolism and Disposition January 2020, 48 (1) 1-7; DOI: https://doi.org/10.1124/dmd.119.089268
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NRF2-Independent Regulation of Intestinal Constitutive Androstane Receptor by the Pro-Oxidants Cadmium and Isothiocyanate in hUGT1 Mice
Miles Paszek and Robert H. Tukey

Drug Metabolism and Disposition January 2020, 48 (1) 25-30; DOI: https://doi.org/10.1124/dmd.119.089508
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Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma
Christine M. Bowman, Eugene Chen, Liuxi Chen, Yi-Chen Chen, Xiaorong Liang, Matthew Wright, Yuan Chen and Jialin Mao

Drug Metabolism and Disposition January 2020, 48 (1) 18-24; DOI: https://doi.org/10.1124/dmd.119.088948
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A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity
Veronica Krogstad, Alexandra Peric, Ida Robertsen, Marianne K. Kringen, Christine Wegler, Philip Carlo Angeles, Jøran Hjelmesæth, Cecilia Karlsson, Shalini Andersson, Per Artursson, Anders Åsberg, Tommy B. Andersson and Hege Christensen

Drug Metabolism and Disposition January 2020, 48 (1) 8-17; DOI: https://doi.org/10.1124/dmd.119.087940
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Abundant expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1 and xCT transporters in blood-arachnoid barrier of pig, and polarized localizations at CSF- and blood-facing plasma membranes
Yasuo Uchida, Ryohei Goto, Hina Takeuchi, Magdalena Łuczak, Takuya Usui, Masanori Tachikawa and Tetsuya Terasaki

Drug Metabolism and Disposition November 26, 2019, dmd.119.089516; DOI: https://doi.org/10.1124/dmd.119.089516
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Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-mediated Uptake
Bridget L. Morse, Anil Kolur, Loyd R Hudson, Andrew T. Hogan, Lisa Hong Chen, Ryan M. Brackman, Geri A. Sawada, John K. Fallon, Philip C. Smith and Kathleen M. Hillgren

Drug Metabolism and Disposition November 26, 2019, dmd.119.088781; DOI: https://doi.org/10.1124/dmd.119.088781
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Human Cytochrome P450 1A1 Adapts Active Site for Atypical Nonplanar Substrate
Aaron G. Bart, Ryan H. Takahashi, Xiaojing Wang and Emily E. Scott

Drug Metabolism and Disposition November 22, 2019, dmd.119.089607; DOI: https://doi.org/10.1124/dmd.119.089607
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Toxicokinetic Interaction between Hepatic Disposition and Pulmonary Bioactivation of Inhaled Naphthalene Studied Using Cyp2abfgs-Null and CYP2A13/2F1-Humanized Mice with Deficient Hepatic Cytochrome P450 Activity
Nataliia Kovalchuk, Qing-Yu Zhang, Jacklyn Kelty, Laura Van Winkle and Xinxin Ding

Drug Metabolism and Disposition December 2019, 47 (12) 1469-1478; DOI: https://doi.org/10.1124/dmd.119.088930
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Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo
Congrong Niu, Yujin Wang, Xiaofeng Zhao, Sam Tep, Eisuke Murakami, Raju Subramanian, Bill Smith and Yurong Lai

Drug Metabolism and Disposition December 2019, 47 (12) 1433-1442; DOI: https://doi.org/10.1124/dmd.119.088922
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Are Biotransformation Studies of Therapeutic Proteins Needed? Scientific Considerations and Technical Challenges
Simone Schadt, Simon Hauri, Filipe Lopes, Martin R. Edelmann, Roland F. Staack, Roberto Villaseñor, Hubert Kettenberger, Adrian B. Roth, Franz Schuler, Wolfgang F. Richter and Christoph Funk

Drug Metabolism and Disposition December 2019, 47 (12) 1443-1456; DOI: https://doi.org/10.1124/dmd.119.088997

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