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Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System
Ayman F. El-Kattan and Manthena V. S. Varma

Drug Metabolism and Disposition May 2018, 46 (5) 729-739; DOI: https://doi.org/10.1124/dmd.117.080044
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Hepatic Transport of 25-Hydroxyvitamin D₃ Conjugates: A Mechanism of 25-Hydroxyvitamin D₃ Delivery to the Intestinal Tract
Chunying Gao, Michael Z. Liao, Lyrialle W. Han, Kenneth E. Thummel and Qingcheng Mao

Drug Metabolism and Disposition May 2018, 46 (5) 581-591; DOI: https://doi.org/10.1124/dmd.117.078881
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Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist

Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
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Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter–Enzyme Interplay
Norikazu Matsunaga, Yukina Fukuchi, Haruo Imawaka and Ikumi Tamai

Drug Metabolism and Disposition May 2018, 46 (5) 680-691; DOI: https://doi.org/10.1124/dmd.117.079236
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Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys
Tsuyoshi Karibe, Tomoki Imaoka, Koji Abe and Osamu Ando

Drug Metabolism and Disposition May 2018, 46 (5) 667-679; DOI: https://doi.org/10.1124/dmd.117.078931
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Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer

Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
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Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn

Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277
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Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes

Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
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Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma

Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
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MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study
Nico Holmstock, Marlies Oorts, Jan Snoeys and Pieter Annaert

Drug Metabolism and Disposition May 2018, 46 (5) 697-703; DOI: https://doi.org/10.1124/dmd.117.079467

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