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Calcitriol and Calcipotriol Modulate Transport Activity of ABC Transporters and Exhibit Selective Cytotoxicity in MRP1-overexpressing Cells
Kee W. Tan, Angelina Sampson, Bremansu Osa-Andrews and Surtaj H. Iram

Drug Metabolism and Disposition December 2018, 46 (12) 1856-1866; DOI: https://doi.org/10.1124/dmd.118.081612
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Regional Differences in Human Intestinal Drug Metabolism
Raditya Iswandana, Marina I. Irianti, Dorenda Oosterhuis, Hendrik S. Hofker, Marjolijn T. Merema, Marina H. de Jager, Henricus A. M. Mutsaers and Peter Olinga

Drug Metabolism and Disposition December 2018, 46 (12) 1879-1885; DOI: https://doi.org/10.1124/dmd.118.083428
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Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics
Niall Heyes, Parth Kapoor and Ian D. Kerr

Drug Metabolism and Disposition December 2018, 46 (12) 1886-1899; DOI: https://doi.org/10.1124/dmd.118.083030
Open Access
Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane
Shaman Luo, Gang Chen, Cristina I. Truica, Cynthia C. Baird, Zuping Xia and Philip Lazarus

Drug Metabolism and Disposition December 2018, 46 (12) 1867-1878; DOI: https://doi.org/10.1124/dmd.118.081166
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6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to β-Estradiol
Kimberly Lapham, Jian Lin, Jonathan Novak, Christine Orozco, Mark Niosi, Li Di, Theunis C. Goosen, Sangwoo Ryu, Keith Riccardi, Heather Eng, Kimberly O. Cameron and Amit S. Kalgutkar

Drug Metabolism and Disposition December 2018, 46 (12) 1836-1846; DOI: https://doi.org/10.1124/dmd.118.083709
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Metabolism of c-Met Kinase Inhibitors Containing Quinoline by Aldehyde Oxidase, Electron Donating, and Steric Hindrance Effect
Jiang Wei Zhang, Wen Xiao, Zhen Ting Gao, Zheng Tian Yu and Ji Yue (Jeff) Zhang

Drug Metabolism and Disposition December 2018, 46 (12) 1847-1855; DOI: https://doi.org/10.1124/dmd.118.081919
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Health-Relevant Phenotypes in the Offspring of Mice Given CAR Activators Prior to Pregnancy
Karin Dietrich, Jan Baumgart, Leonid Eshkind, Lea Reuter, Ute Gödtel-Armbrust, Elke Butt, Michael Musheev, Federico Marini, Piyush More, Tanja Grosser, Christof Niehrs, Leszek Wojnowski and Marianne Mathäs

Drug Metabolism and Disposition November 2018, 46 (11) 1827-1835; DOI: https://doi.org/10.1124/dmd.118.082925
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Equilibrative Nucleoside Transporter 1 (ENT1, SLC29A1) Facilitates Transfer of the Antiretroviral Drug Abacavir across the Placenta
Lukas Cerveny, Zuzana Ptackova, Martina Ceckova, Rona Karahoda, Sara Karbanova, Lucie Jiraskova, Susan L. Greenwood, Jocelyn D. Glazier and Frantisek Staud

Drug Metabolism and Disposition November 2018, 46 (11) 1817-1826; DOI: https://doi.org/10.1124/dmd.118.083329
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Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics
Piyush Bajaj, Swapan K. Chowdhury, Robert Yucha, Edward J. Kelly and Guangqing Xiao

Drug Metabolism and Disposition November 2018, 46 (11) 1692-1702; DOI: https://doi.org/10.1124/dmd.118.082958
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Human Pluripotent Stem Cell–Derived Kidney Model for Nephrotoxicity Studies
Piyush Bajaj, A. David Rodrigues, Claire M. Steppan, Sandra J. Engle, Sumathy Mathialagan and Thomas Schroeter

Drug Metabolism and Disposition November 2018, 46 (11) 1703-1711; DOI: https://doi.org/10.1124/dmd.118.082727

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