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A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou

Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
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Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5
Elaine Tseng, Gwendolyn D. Fate, Gregory S. Walker, Theunis C. Goosen and R. Scott Obach

Drug Metabolism and Disposition May 2018, 46 (5) 493-502; DOI: https://doi.org/10.1124/dmd.117.079855
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Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang

Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
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Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells
Daichi Onozato, Misaki Yamashita, Anna Nakanishi, Takumi Akagawa, Yuriko Kida, Isamu Ogawa, Tadahiro Hashita, Takahiro Iwao and Tamihide Matsunaga

Drug Metabolism and Disposition April 3, 2018, dmd.118.080374; DOI: https://doi.org/10.1124/dmd.118.080374
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Correction to “A Study on Pharmacokinetics of Bosentan with Systems Modeling, Part 1: Translating Systemic Plasma Concentration to Liver Exposure in Healthy Subjects”
Drug Metabolism and Disposition April 2018, 46 (4) 483; DOI: https://doi.org/10.1124/dmd.117.078790err
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Correction to “A Study on Pharmacokinetics of Bosentan with Systems Modeling, Part 2: Prospectively Predicting Systemic and Liver Exposure in Healthy Subjects”
Drug Metabolism and Disposition April 2018, 46 (4) 484; DOI: https://doi.org/10.1124/dmd.117.078808err
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Identification of Galeterone and Abiraterone as Inhibitors of Dehydroepiandrosterone Sulfonation Catalyzed by Human Hepatic Cytosol, SULT2A1, SULT2B1b, and SULT1E1
Caleb Keng Yan Yip, Sumit Bansal, Siew Ying Wong and Aik Jiang Lau

Drug Metabolism and Disposition April 2018, 46 (4) 470-482; DOI: https://doi.org/10.1124/dmd.117.078980
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LC-MS Differential Analysis for Fast and Sensitive Determination of Biotransformation of Therapeutic Proteins
Ming Yao, Bingming Chen, Weiping Zhao, John T. Mehl, Lingjun Li and Mingshe Zhu

Drug Metabolism and Disposition April 2018, 46 (4) 451-457; DOI: https://doi.org/10.1124/dmd.117.077792
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Identification of Ketene-Reactive Intermediate of Erlotinib Possibly Responsible for Inactivation of P450 Enzymes
Huimin Zhao, Siyuan Li, Zixin Yang, Ying Peng, Xiaohui Chen and Jiang Zheng

Drug Metabolism and Disposition April 2018, 46 (4) 442-450; DOI: https://doi.org/10.1124/dmd.117.079327
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Mathematical and Experimental Validation of Flux Dialysis Method: An Improved Approach to Measure Unbound Fraction for Compounds with High Protein Binding and Other Challenging Properties
J. Cory Kalvass, Colin Phipps, Gary J. Jenkins, Patricia Stuart, Xiaomei Zhang, Lance Heinle, Marjoleen J. M. A. Nijsen and Volker Fischer

Drug Metabolism and Disposition April 2018, 46 (4) 458-469; DOI: https://doi.org/10.1124/dmd.117.078915

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