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Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice
Shujuan Chen and Robert H. Tukey

Drug Metabolism and Disposition November 2018, 46 (11) 1745-1755; DOI: https://doi.org/10.1124/dmd.118.083212
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Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier
Yamato Sano, Tadahaya Mizuno, Tatsuki Mochizuki, Yasuo Uchida, Mina Umetsu, Tetsuya Terasaki and Hiroyuki Kusuhara

Drug Metabolism and Disposition November 2018, 46 (11) 1767-1775; DOI: https://doi.org/10.1124/dmd.118.081877
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How to Determine the Role of the Microbiome in Drug Disposition
Jordan E. Bisanz, Peter Spanogiannopoulos, Lindsey M. Pieper, Annamarie E. Bustion and Peter J. Turnbaugh

Drug Metabolism and Disposition November 2018, 46 (11) 1588-1595; DOI: https://doi.org/10.1124/dmd.118.083402
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Physiologically Relevant, Humanized Intestinal Systems to Study Metabolism and Transport of Small Molecule Therapeutics
Aarti Sawant-Basak, A. David Rodrigues, Matthew Lech, Regis Doyonnas, Marion Kasaian, Bhagwat Prasad and Nikolaos Tsamandouras

Drug Metabolism and Disposition November 2018, 46 (11) 1581-1587; DOI: https://doi.org/10.1124/dmd.118.082784
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Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics
Piyush Bajaj, Swapan K. Chowdhury, Robert Yucha, Edward J. Kelly and Guangqing Xiao

Drug Metabolism and Disposition November 2018, 46 (11) 1692-1702; DOI: https://doi.org/10.1124/dmd.118.082958
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Human Pluripotent Stem Cell–Derived Kidney Model for Nephrotoxicity Studies
Piyush Bajaj, A. David Rodrigues, Claire M. Steppan, Sandra J. Engle, Sumathy Mathialagan and Thomas Schroeter

Drug Metabolism and Disposition November 2018, 46 (11) 1703-1711; DOI: https://doi.org/10.1124/dmd.118.082727
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An Ex Vivo Fermentation Screening Platform to Study Drug Metabolism by Human Gut Microbiota
E. van de Steeg, F. H. J. Schuren, R. Scott Obach, C. van Woudenbergh, Gregory S. Walker, M. Heerikhuisen, I. H. G. Nooijen and W. H. J. Vaes

Drug Metabolism and Disposition November 2018, 46 (11) 1596-1607; DOI: https://doi.org/10.1124/dmd.118.081026
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Gene-by-Environment Interaction of Bcrp^−/− and Methionine- and Choline-Deficient Diet–Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition
Erica L. Toth, Hui Li, Anika L. Dzierlenga, John D. Clarke, Anna Vildhede, Michael Goedken and Nathan J. Cherrington

Drug Metabolism and Disposition November 2018, 46 (11) 1478-1486; DOI: https://doi.org/10.1124/dmd.118.082081
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When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interactions
Gabriela I. Patilea-Vrana and Jashvant D. Unadkat

Drug Metabolism and Disposition November 2018, 46 (11) 1487-1496; DOI: https://doi.org/10.1124/dmd.118.081307
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Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
Franco Lombardo, Giuliano Berellini and R. Scott Obach

Drug Metabolism and Disposition November 2018, 46 (11) 1466-1477; DOI: https://doi.org/10.1124/dmd.118.082966

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