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Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald

Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615
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The Human UGT2B7 Nanodisc
Ian Cook, Anna B. Asenjo, Hernando Sosa and Thomas S. Leyh

Drug Metabolism and Disposition March 2020, 48 (3) 198-204; DOI: https://doi.org/10.1124/dmd.119.089946
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Biotransformation Pathways and Metabolite Profiles of Oral [¹⁴C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury

Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338
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UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues
Ana G. Vergara, Christy J.W. Watson, Gang Chen and Philip Lazarus

Drug Metabolism and Disposition March 2020, 48 (3) 160-168; DOI: https://doi.org/10.1124/dmd.119.089284
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Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler

Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482
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Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill

Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326
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Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta

Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052
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Drug interactions for low dose inhaled nemiralisib - a case study integrating modelling, in vitro and clinical investigations
Aarti Patel, Robert Wilson, Andrew W Harrell, Kunal S Taskar, Maxine Taylor, Helen Tracey, Kylie Riddell, Alex Georgiou, Anthony P Cahn, Miriam Marotti and Edith M Hessel

Drug Metabolism and Disposition February 2, 2020, dmd.119.089003; DOI: https://doi.org/10.1124/dmd.119.089003
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Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai

Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011
Open Access
Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel

Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

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