Data Supplement
Files in this Data Supplement:
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Supplemental Table 1 - Comparison of pharmacodynamic parameter estimates for PF06463922- and PF06471402-mediated ALK inhibition between the indirect response and precursor models
Supplemental Figure 1 - Indirect response model-fitted and observed ALK inhibition by PF06463922 (S1 and S2) and PF06471402 (S3 and S4) in athymic mice implanted with H3122 NSCLC cells expressing EML4-ALKL1196M following repeated oral administration (A) or subcutaneous infusion (B)