Data Supplement
- Supplemental Data -
Method to Estimate the Concentration-Dependent Permeability of Cefadroxil in Mouse
Intestinal Segments during Single Escalating Doses and during Multiple DosingSupplemental Table 1 - Model fitting of permeability parameters in wildtype (WT) and humanized (hu) PepT1 mice
Supplemental Table 2 - Observed and predicted intestinal Peff of cefadroxil in wildtype (WT) and humanized (hu) PepT1 mice when estimated by the in situ permeability of small and large intestines
Supplemental Figure 1 - The concentration-dependent jejunal permeability of cefadroxil in wildtype (panel A) and humanized mice (panel B)