Articles:

HA Semple and F Xia

Propranolol disposition in the single-pass isolated, perfused rat liver in the presence and absence of insulin and glucagon
Drug Metab Dispos 1994 22: 822-826. [Abstract] [PDF]  

MA Sarkar and BJ Jackson

Theophylline N-demethylations as probes for P4501A1 and P4501A2
Drug Metab Dispos 1994 22: 827-834. [Abstract] [PDF]  

FP Lacreta, JM Brennan, TC Hamilton, RF Ozols, and PJ O'Dwyer

Stereoselective pharmacokinetics of L-buthionine SR-sulfoximine in patients with cancer
Drug Metab Dispos 1994 22: 835-842. [Abstract] [PDF]  

E Ezan, P Carde, J Le Kerneau, T Ardouin, F Thomas, F Isnard, E Deschamps de Paillette, and JM Grognet

Pharmcokinetics in healthy volunteers and patients of NAc-SDKP (seraspenide), a negative regulator of hematopoiesis
Drug Metab Dispos 1994 22: 843-848. [Abstract] [PDF]  

M Jurima-Romet, K Crawford, T Cyr, and T Inaba

Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals
Drug Metab Dispos 1994 22: 849-857. [Abstract] [PDF]  

C Kim, RO Manning, RP Brown, and JV Bruckner

A comprehensive evaluation of the vial equilibration method for quantification of the metabolism of volatile organic chemicals. Trichloroethylene
Drug Metab Dispos 1994 22: 858-865. [Abstract] [PDF]  

KB Alton, TM Chan, and BN Pramanik

Urinary metabolites of (R),(R)-labetalol
Drug Metab Dispos 1994 22: 866-872. [Abstract] [PDF]  

JB Mangold, HF Schran, and FL Tse

Pharmacokinetics and metabolism of cyclosporin G in humans
Drug Metab Dispos 1994 22: 873-879. [Abstract] [PDF]  

JF Denissen, BA Grabowski, MK Johnson, SA Boyd, JT Uchic, H Stein, S Cepa, and P Hill

The orally active renin inhibitor A-74273. In vivo and in vitro morpholine ring metabolism in rats, dogs, and humans
Drug Metab Dispos 1994 22: 880-888. [Abstract] [PDF]  

M Hosokawa, K Hirata, F Nakata, T Suga, and T Satoh

Species differences in the induction of hepatic microsomal carboxylesterases caused by dietary exposure to di(2- ethylhexyl)phthalate, a peroxisome proliferator
Drug Metab Dispos 1994 22: 889-894. [Abstract] [PDF]  

LM Shaw, HS Bonner, and DQ Brown

Metabolic pathways of WR-2721 (ethyol, amifostine) in the BALB/c mouse
Drug Metab Dispos 1994 22: 895-902. [Abstract] [PDF]  

LE Los, SM Pitzenberger, HG Ramjit, AB Coddington, and HD Colby

Hepatic metabolism of spironolactone. Production of 3-hydroxy- thiomethyl metabolites
Drug Metab Dispos 1994 22: 903-908. [Abstract] [PDF]  

Y Masubuchi, S Hosokawa, T Horie, T Suzuki, S Ohmori, M Kitada, and S Narimatsu

Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase
Drug Metab Dispos 1994 22: 909-915. [Abstract] [PDF]  

T Hasegawa, K Hara, T Kenmochi, and S Hata

In vitro metabolism of dorzolamide, a novel potent carbonic anhydrase inhibitor, in rat liver microsomes
Drug Metab Dispos 1994 22: 916-921. [Abstract] [PDF]  

SR Babu, VM Lakshmi, TV Zenser, and BB Davis

Glucuronidation of N-acetylbenzidine by human liver
Drug Metab Dispos 1994 22: 922-927. [Abstract] [PDF]  

G Tzimas, JO Sass, W Wittfoht, MM Elmazar, K Ehlers, and H Nau

Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13-dicis-retinoic acid to the mouse and rat embryos
Drug Metab Dispos 1994 22: 928-936. [Abstract] [PDF]  

SS Dehal and D Kupfer

Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B
Drug Metab Dispos 1994 22: 937-946. [Abstract] [PDF]  

KS Lown, JC Kolars, KE Thummel, JL Barnett, KL Kunze, SA Wrighton, and PB Watkins

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test [published erratum appears in Drug Metab Dispos 1995 Mar;23(3):following table of contents]
Drug Metab Dispos 1994 22: 947-955. [Abstract] [PDF]  

A Kretz-Rommel and UA Boelsterli

Mechanism of covalent adduct formation of diclofenac to rat hepatic microsomal proteins. Retention of the glucuronic acid moiety in the adduct
Drug Metab Dispos 1994 22: 956-961. [Abstract] [PDF]  

L Paroli, C Lee, and AB Rifkind

Identification of hepatocytes as the major locus of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced CYP1-related P450s, TCDDAA and TCDDAHH, in chick embryo liver
Drug Metab Dispos 1994 22: 962-968. [Abstract] [PDF]  

AE Cribb, GP Griffin, SP Spielberg, TH Rushmore, N Chauret, and DA Nicoll-Griffith

Increased cosedimentation of cytosolic glutathione S-transferases with microsomal fractions prepared from frozen rat liver
Drug Metab Dispos 1994 22: 969-972. [PDF]  

H Heyn, YG Bankmann, and MW Anders

Tissue distribution and stereoselectivity of remacemide-glycine hydrolase
Drug Metab Dispos 1994 22: 973-974. [PDF]  

SD Hall, MA Hamman, AE Rettie, LC Wienkers, WF Trager, M Vandenbranden, and SA Wrighton

Relationships between the levels of cytochrome P4502C9 and its prototypic catalytic activities in human liver microsomes
Drug Metab Dispos 1994 22: 975-978. [PDF]  

Letters:

I Linhart

Solvolysis of butadiene monoxide [letter; comment]
Drug Metab Dispos 1994 22: 820-821. [PDF]  

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