DMD -- Table of Contents (28 [6])

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June 2000; 28 (6)   [Index by Author] [Cover Caption]

       Articles

       Short Communications

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Articles:

John S. Markowitz, C. Lindsay DeVane, David W. Boulton, Ziad Nahas, S. Craig Risch, Fran Diamond, and Kennerly S. Patrick: Ethylphenidate Formation in Human Subjects after the Administration of a Single Dose of Methylphenidate and Ethanol
Drug Metab Dispos 2000 28: 620-624. [Abstract] [Full Text] [PDF]

Vinita Uttamsingh, Raymond B. Baggs, Daria M. Krenitsky, and M. W. Anders: Immunohistochemical Localization of the Acylases that Catalyze the Deacetylation of N-Acetyl-L-cysteine and Haloalkene-Derived Mercapturates
Drug Metab Dispos 2000 28: 625-632. [Abstract] [Full Text] [PDF]

Kanyin E. Zhang, Prasad H. Kari, Margaret R. Davis, George Doss, Thomas A. Baillie, and Kamlesh P. Vyas: Metabolism of A Dopamine D₄-Selective Antagonist in Rat, Monkey, and Humans: Formation of A Novel Mercapturic Acid Adduct
Drug Metab Dispos 2000 28: 633-642. [Abstract] [Full Text] [PDF]

Stefano Evangelista, Pascal Cochet, Norbert Bromet, Marco Criscuoli, and Carlo Alberto Maggi: A Distribution Study with ¹⁴C-Otilonium Bromide in The Rat: Evidence for Selective Tropism for Large Intestine after Oral Administration
Drug Metab Dispos 2000 28: 643-647. [Abstract] [Full Text] [PDF]

Caroline Teyssier and Marie-Hélène Siess: Metabolism of Dipropyl Disulfide by Rat Liver Phase I and Phase II Enzymes and by Isolated Perfused Rat Liver
Drug Metab Dispos 2000 28: 648-654. [Abstract] [Full Text] [PDF]

Edna F. Choo, Brenda Leake, Christoph Wandel, Hitoshi Imamura, Alastair J. J. Wood, Grant R. Wilkinson, and Richard B. Kim: Pharmacological Inhibition of P-glycoprotein Transport Enhances the Distribution of HIV-1 Protease Inhibitors into Brain and Testes
Drug Metab Dispos 2000 28: 655-660. [Abstract] [Full Text] [PDF]

Christopher King, Bernita Finley, and Ronald Franklin: The Glucuronidation of Morphine by Dog Liver Microsomes: Identification of Morphine-6-O-Glucuronide
Drug Metab Dispos 2000 28: 661-663. [Abstract] [Full Text] [PDF]

Philmore Robertson, Heleen H. DeCory, Ajay Madan, and Andrew Parkinson: In Vitro Inhibition and Induction of Human Hepatic Cytochrome P450 Enzymes by Modafinil
Drug Metab Dispos 2000 28: 664-671. [Abstract] [Full Text] [PDF]

Cheryl L. Zimmerman, Yandong Wen, and Rory P. Remmel: First-Pass Disposition of ( $-$ )-6-Aminocarbovir in Rats: II. Inhibition of Intestinal First-Pass Metabolism
Drug Metab Dispos 2000 28: 672-679. [Abstract] [Full Text] [PDF]

Cuyue Tang, Masato Chiba, Joy Nishime, Jerome H. Hochman, I.-Wu Chen, Theresa M. Williams, and Jiunn H. Lin: Comparison of Imidazole- and 2-Methyl Imidazole-Containing Farnesyl-Protein Transferase Inhibitors: Interaction with and Metabolism by Rat Hepatic Cytochrome P450s
Drug Metab Dispos 2000 28: 680-686. [Abstract] [Full Text] [PDF]

Kunihiro Yoshisue, Yoshio Yamamoto, Ken-Ichiro Yoshida, Mayuko Saeki, Yoshinori Minami, Yoshio Esumi, and Yasuro Kawaguchi: Pharmacokinetics and Biological Fate of 3-(2,2,2-Trimethylhydrazinium)Propionate Dihydrate (MET-88), a Novel Cardioprotective Agent, in Rats
Drug Metab Dispos 2000 28: 687-694. [Abstract] [Full Text] [PDF]

Anna-Karin Sohlenius-Sternbeck, Hans Von Euler Chelpin, Achim Orzechowski, and Magnus M. Halldin: Metabolism of Sameridine to Monocarboxylated Products by Hepatocytes Isolated from the Male Rat
Drug Metab Dispos 2000 28: 695-700. [Abstract] [Full Text] [PDF]

Jennifer J. Schlezinger and John J. Stegeman: Dose and Inducer-Dependent Induction of Cytochrome P450 1A in Endothelia of the Eel, including in the Swimbladder Rete Mirabile, a Model Microvascular Structure
Drug Metab Dispos 2000 28: 701-708. [Abstract] [Full Text] [PDF]

Jinmei Pan, Qian Xiang, and Simon Ball: Use of a Novel Real-Time Quantitative Reverse Transcription-Polymerase Chain Reaction Method to Study the Effects of Cytokines on Cytochrome P450 mRNA Expression in Mouse Liver
Drug Metab Dispos 2000 28: 709-713. [Abstract] [Full Text] [PDF]

Short Communications:

Monique Vincent-Viry, Blandine Fournier, and Marie-Madeleine Galteau: Short Communication. The Effects of Drinking and Smoking on the CYP2D6 Metabolic Capacity
Drug Metab Dispos 2000 28: 617-619. [Abstract] [Full Text] [PDF]

Cover Caption:

Effect of P-gp inhibitors (dose shown is per kilogram of body weight) on brain/plasma and testes/plasma distribution ratiosof [¹⁴C]nelfinavir in wild-type mdr1a(+/+) and mdr1a( $-$ / $-$ ) mice. Seethe article by Choo et al. on page 655 of thisissue.