Articles:

Timothy Schulz-Utermoehl, Richard J. Mountfield, Robert P. Bywater, Kjeld Madsen, Peer N. Jørgensen, and Kristian T. Hansen

Structure-Function Analysis of Human CYP3A4 Using a Specific Proinhibitory Antipeptide Antibody
Drug Metab Dispos 2000 28: 718-725. [Abstract] [Full Text] [PDF]  

Zhao Chao Liu and Jack P. Uetrecht

Metabolism of Ticlopidine by Activated Neutrophils: Implications for Ticlopidine-Induced Agranulocytosis
Drug Metab Dispos 2000 28: 726-730. [Abstract] [Full Text] [PDF]  

Yong Liu, Edward R. Bacon, Kelly Ballinger, Christopher D. V. Black, Kathleen Illig, Gregory L. McIntire, Ping Ping Wang, Nancy O'Neil, Lew Kinter, and Vinay C. Desai

Pharmacokinetics and Hepatic Disposition of Bis[1-(ethoxycarbonyl)propyl]5-acetylamino-2,4,6-triiodoisophthalate in Rats and Isolated Perfused Rat Livers
Drug Metab Dispos 2000 28: 731-736. [Abstract] [Full Text] [PDF]  

David J. Sweeny, Geoffrey Lynch, Alison M. Bidgood, Willard Lew, Ke-Yu Wang, and Kenneth C. Cundy

Metabolism of the Influenza Neuraminidase Inhibitor Prodrug Oseltamivir in the Rat
Drug Metab Dispos 2000 28: 737-741. [Abstract] [Full Text] [PDF]  

Joel W. Proksch, W. Brooks Gentry, and S. Michael Owens

The Effect of Rate of Drug Administration on the Extent and Time Course of Phencyclidine Distribution in Rat Brain, Testis, and Serum
Drug Metab Dispos 2000 28: 742-747. [Abstract] [Full Text] [PDF]  

Philip G. Hewitt, John Perkins, and Sharon A. M. Hotchkiss

Metabolism of Fluroxypyr, Fluroxypyr Methyl Ester, and the Herbicide Fluroxypyr Methylheptyl Ester. I: During Percutaneous Absorption through Fresh Rat and Human Skin In Vitro
Drug Metab Dispos 2000 28: 748-754. [Abstract] [Full Text] [PDF]  

Philip G. Hewitt, John Perkins, and Sharon A. M. Hotchkiss

Metabolism of Fluroxypyr, Fluroxypyr Methyl Ester, and the Herbicide Fluroxypyr Methylheptyl Ester. II: In Rat Skin Homogenates
Drug Metab Dispos 2000 28: 755-759. [Abstract] [Full Text] [PDF]  

Darrell R. Abernethy, Irving W. Wainer, and Ana Isabel Anacleto

Verapamil Metabolite Exposure in Older and Younger Men during Steady-State Oral Verapamil Administration
Drug Metab Dispos 2000 28: 760-765. [Abstract] [Full Text] [PDF]  

Lian-Qing Guo, Katsuyuki Fukuda, Tomihisa Ohta, and Yasushi Yamazoe

Role of Furanocoumarin Derivatives on Grapefruit Juice-Mediated Inhibition of Human CYP3A Activity
Drug Metab Dispos 2000 28: 766-771. [Abstract] [Full Text] [PDF]  

Peter J. Cox, David A. Ryan, Frank J. Hollis, Ann-Marie Harris, Ann K. Miller, Marika Vousden, and Hugh Cowley

Absorption, Disposition, and Metabolism of Rosiglitazone, a Potent Thiazolidinedione Insulin Sensitizer, in Humans
Drug Metab Dispos 2000 28: 772-780. [Abstract] [Full Text] [PDF]  

Wayne P. Bowen, Jae E. Carey, Asik Miah, Heather F. McMurray, Peter W. Munday, Rowena S. James, Robert A. Coleman, and Anthony M. Brown

Measurement of Cytochrome P450 Gene Induction in Human Hepatocytes using Quantitative Real-Time Reverse Transcriptase-Polymerase Chain Reaction
Drug Metab Dispos 2000 28: 781-788. [Abstract] [Full Text] [PDF]  

Zeruesenay Desta, Nadia Soukhova, Subena K. Mahal, and David A. Flockhart

Interaction of Cisapride with the Human Cytochrome P450 System: Metabolism and Inhibition Studies
Drug Metab Dispos 2000 28: 789-800. [Abstract] [Full Text] [PDF]  

Tawfic Nessim Abu-Zahra, Allan W. Wolkoff, Richard B. Kim, and K. Sandy Pang

Uptake of Enalapril and Expression of Organic Anion Transporting Polypeptide 1 in Zonal, Isolated Rat Hepatocytes
Drug Metab Dispos 2000 28: 801-806. [Abstract] [Full Text] [PDF]  

Tawfic Nessim Abu-Zahra and K. Sandy Pang

Effect of Zonal Transport and Metabolism on Hepatic Removal: Enalapril Hydrolysis in Zonal, Isolated Rat Hepatocytes In Vitro and Correlation with Perfusion Data
Drug Metab Dispos 2000 28: 807-813. [Abstract] [Full Text] [PDF]  

Christine M. Dieckhaus, Thomas A. Miller, R. Duane Sofia, and Timothy L. Macdonald

A Mechanistic Approach to Understanding Species Differences in Felbamate Bioactivation: Relevance to Drug-Induced Idiosyncratic Reactions
Drug Metab Dispos 2000 28: 814-822. [Abstract] [Full Text] [PDF]  

Sashi V. Gopaul, Kevin Farrell, and Frank S. Abbott

Identification and Characterization of N-Acetylcysteine Conjugates of Valproic Acid in Humans and Animals
Drug Metab Dispos 2000 28: 823-832. [Abstract] [Full Text] [PDF]  

Hirekodathakallu V. Thulasiram, Andanappa K. Gadad, and Madhava K. Madyastha

Role of C-5 Chiral Center in R-(+)-Pulegone-Mediated Hepatotoxicity: Metabolic Disposition and Toxicity of 5,5-Dimethyl-2-(1-Methylethylidene)-Cyclohexanone in Rats
Drug Metab Dispos 2000 28: 833-844. [Abstract] [Full Text] [PDF]  

Sanjeev Kumar, Harvey Wong, Sam Au Yeung, K. Wayne Riggs, Frank S. Abbott, and Dan W. Rurak

Disposition of Valproic Acid in Maternal, Fetal, and Newborn Sheep I: Placental Transfer, Plasma Protein Binding, and Clearance
Drug Metab Dispos 2000 28: 845-856. [Abstract] [Full Text] [PDF]  

Sanjeev Kumar, Harvey Wong, Sam Au Yeung, K. Wayne Riggs, Frank S. Abbott, and Dan W. Rurak

Disposition of Valproic Acid in Maternal, Fetal, and Newborn Sheep II: Metabolism and Renal Elimination
Drug Metab Dispos 2000 28: 857-864. [Abstract] [Full Text] [PDF]  

Accelerated Communications:

Timothy Schulz-Utermoehl, Richard J. Mountfield, Kjeld Madsen, Peer N. Jørgensen, and Kristian T. Hansen

Selective and Potent Inhibition of Human CYP2C19 Activity by a Conformationally Targeted Antipeptide Antibody
Drug Metab Dispos 2000 28: 715-717. [Abstract] [Full Text] [PDF]  

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