Articles:

George F. Cawley, Shuxin Zhang, Russell W. Kelley, and Wayne L. Backes

Evidence Supporting the Interaction of CYP2B4 and CYP1A2 in Microsomal Preparations
Drug Metab Dispos 2001 29: 1529-1534. [Abstract] [Full Text] [PDF]  

Benedetta C. Sallustio and Felicity L. Holbrook

In Vivo Perturbation of Rat Hepatocyte Canalicular Membrane Function by Diclofenac
Drug Metab Dispos 2001 29: 1535-1538. [Abstract] [Full Text] [PDF]  

Diem Cong, Angela K. Y. Fong, Ronita Lee, and K. Sandy Pang

Absorption of Benzoic Acid in Segmental Regions of the Vascularly Perfused Rat Small Intestine Preparation
Drug Metab Dispos 2001 29: 1539-1547. [Abstract] [Full Text] [PDF]  

Robin E. Pearce, R. Russell Gotschall, Gregory L. Kearns, and J. Steven Leeder

Cytochrome P450 Involvement in the Biotransformation of Cisapride and Racemic Norcisapride in Vitro: Differential Activity of Individual Human CYP3A Isoforms
Drug Metab Dispos 2001 29: 1548-1554. [Abstract] [Full Text] [PDF]  

Ji-Yeon Kim, Minsun Baek, Sooyong Lee, Sung-Ok Kim, Mi-Sook Dong, Bok-Ryang Kim, and Dong-Hyun Kim

Characterization of the Selectivity and Mechanism of Cytochrome P450 Inhibition by Dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate
Drug Metab Dispos 2001 29: 1555-1560. [Abstract] [Full Text] [PDF]  

Vsevolod E. Kostrubsky, Mary Vore, Erick Kindt, James Burliegh, Karen Rogers, Gregory Peter, Douglas Altrogge, and Michael W. Sinz

The Effect of Troglitazone Biliary Excretion on Metabolite Distribution and Cholestasis in Transporter-Deficient Rats
Drug Metab Dispos 2001 29: 1561-1566. [Abstract] [Full Text] [PDF]  

Ling-Jen Chen, Edward H. Lebetkin, and Leo T. Burka

Metabolism of (R)-(+)-Pulegone in F344 Rats
Drug Metab Dispos 2001 29: 1567-1577. [Abstract] [Full Text] [PDF]  

Rominder Singh, I-Wu Chen, Lixia Jin, Maria V. Silva, Byron H. Arison, Jiunn H. Lin, and Bradley K. Wong

Pharmacokinetics and Metabolism of a Ras Farnesyl Transferase Inhibitor in Rats and Dogs: In Vitro-In Vivo Correlation
Drug Metab Dispos 2001 29: 1578-1587. [Abstract] [Full Text] [PDF]  

Christopher R. Gibson, Alfred E. Staubus, Rolf F. Barth, Weilian Yang, Nan M. Kleinholz, R. Benjamin Jones, Kari Green-Church, Werner Tjarks, and Albert H. Soloway

Boron Neutron Capture Therapy of Brain Tumors: Investigation of Urinary Metabolites and Oxidation Products of Sodium Borocaptate by Electrospray Ionization Mass Spectrometry
Drug Metab Dispos 2001 29: 1588-1598. [Abstract] [Full Text] [PDF]  

R. Scott Obach

Mechanism of Cytochrome P4503A4- and 2D6-Catalyzed Dehydrogenation of Ezlopitant as Probed with Isotope Effects Using Five Deuterated Analogs
Drug Metab Dispos 2001 29: 1599-1607. [Abstract] [Full Text] [PDF]  

Grace K. Poon, Qing Chen, Yohannes Teffera, Jason S. Ngui, Patrick R. Griffin, Mathew P. Braun, George A. Doss, Christopher Freeden, Ralph A. Stearns, David C. Evans, Thomas A. Baillie, and Wei Tang

Bioactivation of Diclofenac via Benzoquinone Imine IntermediatesIdentification of Urinary Mercapturic Acid Derivatives in Rats and Humans
Drug Metab Dispos 2001 29: 1608-1613. [Abstract] [Full Text] [PDF]  

Thomas A. Baillie, Rita A. Halpin, Bogdan K. Matuszewski, Leslie A. Geer, Cynthia M. Chavez-Eng, Dennis Dean, Matthew Braun, George Doss, Allen Jones, Tina Marks, David Melillo, and Kamlesh P. Vyas

Mechanistic Studies on the Reversible Metabolism of Rofecoxib to 5-Hydroxyrofecoxib in the Rat: Evidence for Transient Ring Opening of a Substituted 2-Furanone Derivative Using Stable Isotope-Labeling Techniques.
Drug Metab Dispos 2001 29: 1614-1628. [Abstract] [Full Text] [PDF]  

John R. Cashman, Jun Zhang, James Leushner, and Andreas Braun

Population Distribution of Human Flavin-Containing Monooxygenase Form 3: Gene Polymorphisms
Drug Metab Dispos 2001 29: 1629-1637. [Abstract] [Full Text] [PDF]  

Jim Fang, Gordon McKay, Jiuxue Song, Alfread Remillrd, Xinmin Li, and Kamal Midha

In Vitro Characterization of the Metabolism of Haloperidol Using Recombinant Cytochrome P450 Enzymes and Human Liver Microsomes
Drug Metab Dispos 2001 29: 1638-1643. [Abstract] [Full Text] [PDF]  

Kathryn E. Kenworthy, Stephen E. Clarke, Julie Andrews, and J. Brian Houston

Multisite Kinetic Models for CYP3A4: Simultaneous Activation and Inhibition of Diazepam and Testosterone Metabolism
Drug Metab Dispos 2001 29: 1644-1651. [Abstract] [Full Text] [PDF]  

Short Communications:

Kayoko Shimoi, Noriko Saka, Ryushi Nozawa, Motoyoshi Sato, Izumi Amano, Tsutomu Nakayama, and Naohide Kinae

Deglucuronidation of a Flavonoid, Luteolin Monoglucuronide, during Inflammation
Drug Metab Dispos 2001 29: 1521-1524. [Abstract] [Full Text] [PDF]  

Omar Ghosheh, Sarvesh C. Vashishtha, and Edward M. Hawes

Formation of the Quaternary Ammonium-Linked Glucuronide of Nicotine in Human Liver Microsomes: Identification and Stereoselectivity in the Kinetics
Drug Metab Dispos 2001 29: 1525-1528. [Abstract] [Full Text] [PDF]  

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