Minireview:

Linda C. Quattrochi and Philip S. Guzelian

CYP3A Regulation: From Pharmacology to Nuclear Receptors
Drug Metab Dispos 2001 29: 615-622. [Abstract] [Full Text] [PDF]  

R. N. Hines, Z. Luo, T. Cresteil, X. Ding, R. A. Prough, J. L. Fitzpatrick, S. L. Ripp, K. C. Falkner, N.-L. Ge, A. Levine, and C. J. Elferink

Molecular Regulation of Genes Encoding Xenobiotic-Metabolizing Enzymes: Mechanisms Involving Endogenous Factors
Drug Metab Dispos 2001 29: 623-633. [Abstract] [Full Text] [PDF]  

Articles:

James A. Yergey, Laird A. Trimble, José Silva, Nathalie Chauret, Chun Li, Michel Therien, Erich Grimm, and Deborah A. Nicoll-Griffith

In Vitro Metabolism of the COX-2 Inhibitor DFU, Including a Novel Glutathione Adduct Rearomatization
Drug Metab Dispos 2001 29: 638-644. [Abstract] [Full Text] [PDF]  

Omar A. Ghosheh, Linda P. Dwoskin, Dennis K. Miller, and Peter A. Crooks

Accumulation of Nicotine and Its Metabolites in Rat Brain After Intermittent or Continuous Peripheral Administration of [2'-¹⁴C]Nicotine
Drug Metab Dispos 2001 29: 645-651. [Abstract] [Full Text] [PDF]  

Anthony R. Jude, Joanna M. Little, Arthur W. Bull, Izabela Podgorski, and Anna Radominska-Pandya

13-Hydroxy- and 13-Oxooctadecadienoic acids: Novel Substrates for Human UDP-Glucuronosyltransferases
Drug Metab Dispos 2001 29: 652-655. [Abstract] [Full Text] [PDF]  

Alex Hemeryck, Cindy A. De Vriendt, and Frans M. Belpaire

Metoprolol-Paroxetine Interaction in Human Liver Microsomes: Stereoselective Aspects and Prediction of the in Vivo Interaction
Drug Metab Dispos 2001 29: 656-663. [Abstract] [Full Text] [PDF]  

Harvey Wong, Dan W. Rurak, Sanjeev Kumar, Eddie Kwan, Frank S. Abbott, and K. Wayne Riggs

Dose-Dependent Pharmacokinetics and Metabolism of Valproic Acid in Newborn Lambs and Adult Sheep
Drug Metab Dispos 2001 29: 664-675. [Abstract] [Full Text] [PDF]  

Alvaro P. M. Bras, Juhani Jänne, Carl W. Porter, and Daniel S. Sitar

Spermidine/Spermine N¹-Acetyltransferase Catalyzes Amantadine Acetylation
Drug Metab Dispos 2001 29: 676-680. [Abstract] [Full Text] [PDF]  

Robert W. Townsend, Anup Zutshi, and Ihor Bekersky

Biodistribution of 4-[¹⁴C]Cholesterol-AmBisome following a Single Intravenous Administration to Rats
Drug Metab Dispos 2001 29: 681-685. [Abstract] [Full Text] [PDF]  

Federico Innocenti, Lalitha Iyer, Jacqueline Ramírez, Mitchell D. Green, and Mark J. Ratain

Epirubicin Glucuronidation Is Catalyzed by Human UDP-Glucuronosyltransferase 2B7
Drug Metab Dispos 2001 29: 686-692. [Abstract] [Full Text] [PDF]  

Sharon K. Krueger, Mei-Fei Yueh, Sarah R. Martin, Clifford B. Pereira, and David E. Williams

Characterization of Expressed Full-Length and Truncated FMO2 from Rhesus Monkey
Drug Metab Dispos 2001 29: 693-700. [Abstract] [Full Text] [PDF]  

Minxia He, Allan E. Rettie, John Neal, and William F. Trager

Metabolism of Sulfinpyrazone Sulfide and Sulfinpyrazone by Human Liver Microsomes and cDNA-Expressed Cytochrome P450s
Drug Metab Dispos 2001 29: 701-711. [Abstract] [Full Text] [PDF]  

Tommy B. Andersson, Helena Sjöberg, Kurt-Jürgen Hoffmann, Alan R. Boobis, Patricia Watts, Robert J. Edwards, Brian G. Lake, Roger J. Price, Anthony B. Renwick, Maria J. Gómez-Lechón, José V. Castell, Magnus Ingelman-Sundberg, Mats Hidestrand, Peter S. Goldfarb, David F. V. Lewis, Laurent Corcos, André Guillouzo, Päivi Taavitsainen, and Olavi Pelkonen

An Assessment of Human Liver-Derived in Vitro Systems to Predict the in Vivo Metabolism and Clearance of Almokalant
Drug Metab Dispos 2001 29: 712-720. [Abstract] [Full Text] [PDF]  

Margaret O. James, Zeen Tong, Laura Rowland-Faux, Changaram S. Venugopal, and Kevin M. Kleinow

Intestinal Bioavailability and Biotransformation of 3-Hydroxybenzo(a)pyrene in an Isolated Perfused Preparation from Channel Catfish, Ictalurus punctatus
Drug Metab Dispos 2001 29: 721-728. [Abstract] [Full Text] [PDF]  

Kanyin E. Zhang, Brian Hee, Caroline A. Lee, Baihong Liang, and Barbara C. M. Potts

Liquid Chromatography-Mass Spectrometry and Liquid Chromatography-NMR Characterization of in Vitro Metabolites of a Potent and Irreversible Peptidomimetic Inhibitor of Rhinovirus 3C Protease
Drug Metab Dispos 2001 29: 729-734. [Abstract] [Full Text] [PDF]  

Philippe Claud, Paul Padovani, Jean-Pierre Guichard, Yves Artur, and Romuald Lainé

Involvement of Semicarbazide-Sensitive Amine Oxidase in Tresperimus Metabolism in Human and in Rat
Drug Metab Dispos 2001 29: 735-741. [Abstract] [Full Text] [PDF]  

Alfonso Lampen, Silke Meyer, and Heinz Nau

Effects of Receptor-Selective Retinoids on CYP26 Gene Expression and Metabolism of All-trans-Retinoic Acid in Intestinal Cells
Drug Metab Dispos 2001 29: 742-747. [Abstract] [Full Text] [PDF]  

Amin A. Nomeir, Charles Ruegg, Matthew Shoemaker, Leonard V. Favreau, Jairam R. Palamanda, Paul Silber, and Chin-chung Lin

Inhibition of CYP3A4 in a Rapid Microtiter Plate Assay Using Recombinant Enzyme and in Human Liver Microsomes Using Conventional Substrates
Drug Metab Dispos 2001 29: 748-753. [Abstract] [Full Text] [PDF]  

Liyue Huang, Stephen A. Wring, Joseph L. Woolley, Kenneth R. Brouwer, Cosette Serabjit-Singh, and Joseph W. Polli

Induction of P-Glycoprotein and Cytochrome P450 3A by HIV Protease Inhibitors
Drug Metab Dispos 2001 29: 754-760. [Abstract] [Full Text] [PDF]  

Markus Walles, Thomas Thum, Karsten Levsen, and Jürgen Borlak

Verapamil Metabolism in Distinct Regions of the Heart and in Cultures of Cardiomyocytes of Adult Rats
Drug Metab Dispos 2001 29: 761-768. [Abstract] [Full Text] [PDF]  

Magnus Jendbro, Carl-Johan Johansson, Per Strandberg, Hanna Falk-Nilsson, and Staffan Edsbäcker

Pharmacokinetics of Budesonide and Its Major Ester Metabolite after Inhalation and Intravenous Administration of Budesonide in the Rat
Drug Metab Dispos 2001 29: 769-776. [Abstract] [Full Text] [PDF]  

Short Communications:

Liyue Huang and Mary Vore

Multidrug Resistance P-Glycoprotein 2 Is Essential for the Biliary Excretion of Indocyanine Green
Drug Metab Dispos 2001 29: 634-637. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Swamy Yeleswaram, Gary M. Pollack, Kim L. R. Brouwer, and E. Stacy Ward

Probenecid-Associated Alterations in Valproic Acid Pharmacokinetics in Rats: Can in Vivo Disposition of Valproate Glucuronide Be Predicted from in Vitro Formation Data?
Drug Metab Dispos 2001 29: 777. [Full Text] [PDF]  

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