Minireviews:

John R. Cashman and Jun Zhang

Interindividual Differences of Human Flavin-Containing Monooxygenase 3: Genetic Polymorphisms and Functional Variation
Drug Metab Dispos 2002 30: 1043-1052. [Abstract] [Full Text] [PDF]  

Rosanna Rinaldi, Erik Eliasson, Stellan Swedmark, and Ralf Morgenstern

Reactive Intermediates and The Dynamics of Glutathione Transferases
Drug Metab Dispos 2002 30: 1053-1058. [Abstract] [Full Text] [PDF]  

Articles:

M. Y. Moridani, S. S. Cheon, S. Khan, and P. J. O'Brien

Metabolic Activation of 4-Hydroxyanisole by Isolated Rat Hepatocytes
Drug Metab Dispos 2002 30: 1063-1069. [Abstract] [Full Text] [PDF]  

Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh, and Lawrence Hogg

Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships
Drug Metab Dispos 2002 30: 1070-1076. [Abstract] [Full Text] [PDF]  

Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang, and Guangdi Wang

In Vitro Metabolism of R(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
Drug Metab Dispos 2002 30: 1077-1086. [Abstract] [Full Text] [PDF]  

Michael B. Fisher, Kwansik Yoon, Marcie L. Vaughn, Timothy J. Strelevitz, and Robert S. Foti

Flavin-Containing Monooxygenase Activity in Hepatocytes and Microsomes: In Vitro Characterization and In Vivo Scaling of Benzydamine Clearance
Drug Metab Dispos 2002 30: 1087-1093. [Abstract] [Full Text] [PDF]  

James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic, and Alex M. Buko

Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1'R*,3R*)-3-Phenyl-1-[(1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
Drug Metab Dispos 2002 30: 1094-1101. [Abstract] [Full Text] [PDF]  

Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim, and David A. Flockhart

Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
Drug Metab Dispos 2002 30: 1102-1107. [Abstract] [Full Text] [PDF]  

Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger, and Leszek Wojnowski

Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
Drug Metab Dispos 2002 30: 1108-1114. [Abstract] [Full Text] [PDF]  

Pramod Upadhyaya, Cheryl L. Zimmerman, and Stephen S. Hecht

Metabolism and Pharmacokinetics of N'-Nitrosonornicotine in the Patas Monkey
Drug Metab Dispos 2002 30: 1115-1122. [Abstract] [Full Text] [PDF]  

Thomas C. Wood, Kenneth L. Johnson, Stephen Naylor, and Richard M. Weinshilboum

Cefazolin Administration and 2-Methyl-1,3,4-Thiadiazole-5-Thiol in Human Tissue: Possible Relationship to Hypoprothrombinemia
Drug Metab Dispos 2002 30: 1123-1128. [Abstract] [Full Text] [PDF]  

I. A. M. de Graaf, C. E. van Meijeren, F. Pekta, and H. J. Koster

Comparison of in Vitro Preparations for Semi-Quantitative Prediction of in Vivo Drug Metabolism
Drug Metab Dispos 2002 30: 1129-1136. [Abstract] [Full Text] [PDF]  

Renee J. Krause, Steven C. Glocke, and Adnan A. Elfarra

Sulfoxides as Urinary Metabolites of S-Allyl-L-Cysteine in Rats: Evidence for the Involvement of Flavin-Containing Monooxygenases
Drug Metab Dispos 2002 30: 1137-1142. [Abstract] [Full Text] [PDF]  

Yasuhiro Masubuchi, Atsushi Ose, and Toshiharu Horie

Diclofenac-Induced Inactivation of CYP3A4 and Its Stimulation by Quinidine
Drug Metab Dispos 2002 30: 1143-1148. [Abstract] [Full Text] [PDF]  

Short Communications:

Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He, and Frank W. Lee

Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
Drug Metab Dispos 2002 30: 1059-1062. [Abstract] [Full Text] [PDF]  

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