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February 2002; 30 (2)   [Index by Author]  [Cover Caption]
       Articles
       Short Communications
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Articles:

R. M. E. Vos, S. F. M. Krebbers, C. H. J. Verhoeven, and L. P. C. Delbressine
The in Vivo Human Metabolism of Tibolone
Drug Metab Dispos 2002 30: 106-112. [Abstract] [Full Text] [PDF]  

Shigeyuki Kitamura, Yuri Shimizu, Yuko Shiraga, Mayumi Yoshida, Kazumi Sugihara, and Shigeru Ohta
Reductive Metabolism of p,p'-DDT and o,p'-DDT by Rat Liver Cytochrome P450
Drug Metab Dispos 2002 30: 113-118. [Abstract] [Full Text] [PDF]  

Virginie Lattard, Christiane Longin-Sauvageon, Joel Lachuer, Paul Delatour, and Etienne Benoit
Cloning, Sequencing, and Tissue-Dependent Expression of Flavin-Containing Monooxygenase (FMO) 1 and FMO3 in the Dog
Drug Metab Dispos 2002 30: 119-128. [Abstract] [Full Text] [PDF]  

Mario Congiu, Maurice L. Mashford, John L. Slavin, and Paul V. Desmond
UDP Glucuronosyltransferase mRNA Levels in Human Liver Disease
Drug Metab Dispos 2002 30: 129-134. [Abstract] [Full Text] [PDF]  

Jasminder Sahi, Eric L. Reyner, Jonathan N. Bauman, Kristina Gueneva-Boucheva, James E. Burleigh, and V. Hayden Thomas
The Effect of Bergamottin on Diazepam Plasma Levels and P450 Enzymes in Beagle Dogs
Drug Metab Dispos 2002 30: 135-140. [Abstract] [Full Text] [PDF]  

Ravindra N. Dhir, Wojciech Dworakowski, and Bernard H. Shapiro
Middle-Age Alterations in the Sexually Dimorphic Plasma Growth Hormone Profiles: Involvement of Growth Hormone-Releasing Factor and Effects on Cytochrome P450 Expression
Drug Metab Dispos 2002 30: 141-147. [Abstract] [Full Text] [PDF]  

T. Gul Altuntas and Evan D. Kharasch
Biotransformation of L-Cysteine S-Conjugates and N-Acetyl-L-Cysteine S-Conjugates of the Sevoflurane Degradation Product Fluoromethyl-2,2-Difluoro-1-(trifluoromethyl)vinyl Ether (Compound A) in Human Kidney in Vitro: Interindividual Variability in N-Acetylation, N-Deacetylation, and beta -Lyase-Catalyzed Metabolism
Drug Metab Dispos 2002 30: 148-154. [Abstract] [Full Text] [PDF]  

Yui Yamamoto, Hiroshi Yamazaki, Tomoko Ikeda, Terumi Watanabe, Haruo Iwabuchi, Miki Nakajima, and Tsuyoshi Yokoi
Formation of a Novel Quinone Epoxide Metabolite of Troglitazone with Cytotoxic to HepG2 Cells
Drug Metab Dispos 2002 30: 155-160. [Abstract] [Full Text] [PDF]  

R. Jaggi, R. S. Addison, A. R. King, B. D. Suthers, and R. G. Dickinson
Conjugation of Desmethylnaproxen in the Rat---A Novel Acyl Glucuronide-Sulfate Diconjugate as a Major Biliary Metabolite
Drug Metab Dispos 2002 30: 161-166. [Abstract] [Full Text] [PDF]  

Kouichi Minato, Naoyuki Koizumi, Seijirou Honma, Kunio Tsukamoto, and Satoshi Iwamura
Pharmacokinetics and Biliary Excretion of Osaterone Acetate, a New Steroidal Antiandrogen, in Dogs
Drug Metab Dispos 2002 30: 167-172. [Abstract] [Full Text] [PDF]  

Caroline Keller, Armin Bruelisauer, Michel Lemaire, and Albert Enz
Brain Pharmacokinetics of a Nonpeptidic Corticotropin-Releasing Factor Receptor Antagonist
Drug Metab Dispos 2002 30: 173-176. [Abstract] [Full Text] [PDF]  

Andrew A. Shaw, Stephen D. Hall, Michael R. Franklin, and Raymond E. Galinsky
The Influence of L-Glutamine on the Depression of Hepatic Cytochrome P450 Activity in Male Rats Caused by Total Parenteral Nutrition
Drug Metab Dispos 2002 30: 177-182. [Abstract] [Full Text] [PDF]  

Peter D. Sadowitz, Bradley A. Hubbard, James C. Dabrowiak, Jerry Goodisman, Kirk A. Tacka, Mehmet K. Aktas, Mary J. Cunningham, Ronald L. Dubowy, and Abdul-Kader Souid
Kinetics of Cisplatin Binding to Cellular DNA and Modulations by Thiol-Blocking Agents and Thiol Drugs
Drug Metab Dispos 2002 30: 183-190. [Abstract] [Full Text] [PDF]  

Mark D. Johnson, Jian Chen, and Bradley D. Anderson
Investigation of the Mechanism of Enhancement of Central Nervous System Delivery of 2'-beta -Fluoro-2',3'-Dideoxyinosine Via a Blood-Brain Barrier Adenosine Deaminase-Activated Prodrug
Drug Metab Dispos 2002 30: 191-198. [Abstract] [Full Text] [PDF]  

Laurence Antonio, Joël-Paul Grillasca, Jyrki Taskinen, Eivor Elovaara, Brian Burchell, Marie-Helene Piet, Brian Ethell, Mohamed Ouzzine, Sylvie Fournel-Gigleux, and Jacques Magdalou
Characterization of Catechol Glucuronidation in Rat Liver
Drug Metab Dispos 2002 30: 199-207. [Abstract] [Full Text] [PDF]  

Satoru Kakizaki, Sohrab Karami, and Masahiko Negishi
Retinoic Acids Repress Constitutive Active Receptor-Mediated Induction by 1,4-bis[2-(3,5-Dichloropyridyloxy)]benzene of the Cyp2b10 Gene in Mouse Primary Hepatocytes
Drug Metab Dispos 2002 30: 208-211. [Abstract] [Full Text] [PDF]  

A. L. Slitt, N. J. Cherrington, D. P. Hartley, T. M. Leazer, and C. D. Klaassen
Tissue Distribution and Renal Developmental Changes in Rat Organic Cation Transporter mRNA levels
Drug Metab Dispos 2002 30: 212-219. [Abstract] [Full Text] [PDF]  

Daisuke Sugiyama, Hiroyuki Kusuhara, Yoshihisa Shitara, Takaaki Abe, and Yuichi Sugiyama
Effect of 17beta -Estradiol-D-17beta -Glucuronide on the Rat Organic Anion Transporting Polypeptide 2-Mediated Transport Differs Depending on Substrates
Drug Metab Dispos 2002 30: 220-223. [Abstract] [Full Text] [PDF]  

Short Communications:

Yoko Otake and Thomas Walle
Oxidation of the Flavonoids Galangin and Kaempferide by Human Liver Microsomes and CYP1A1, CYP1A2, and CYP2C9
Drug Metab Dispos 2002 30: 103-105. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: 13C NMR spectra of the authentic standards A, B, C, and M-3 in CDCl3 and deduced structures. See the article by Yamamoto et al. on page 155 of this issue.



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