Symposium Articles:

Tetsuo Satoh, Palmer Taylor, William F. Bosron, Sonal P. Sanghani, Masakiyo Hosokawa, and Bert N. La Du

Current Progress on Esterases: From Molecular Structure to Function
Drug Metab Dispos 2002 30: 488-493. [Abstract] [Full Text] [PDF]  

Articles:

Norihiro Takenaga, Mikio Ishii, Toshio Kamei, and Toshio Yasumori

Structure-Activity Relationship in O-Glucuronidation of Indolocarbazole Analogs
Drug Metab Dispos 2002 30: 494-497. [Abstract] [Full Text] [PDF]  

Yoshihiro Kawabata, Shigeru Furuta, Yutaka Shinozaki, Tadashi Kurimoto, and Ryuichiro Nishigaki

Carrier-Mediated Active Transport of a Novel Thromboxane A₂ Receptor Antagonist [2-(4-Chlorophenylsulfonylaminomethyl)indan-5-yl]acetate (Z-335) into Rat Liver
Drug Metab Dispos 2002 30: 498-504. [Abstract] [Full Text] [PDF]  

Thomayant Prueksaritanont, Raju Subramanian, Xiaojun Fang, Bennett Ma, Yue Qiu, Jiunn H. Lin, Paul G. Pearson, and Thomas A. Baillie

Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization
Drug Metab Dispos 2002 30: 505-512. [Abstract] [Full Text] [PDF]  

Rongzi Yan and Eve M. Taylor

Neotrofin Is Transported Out of Brain by a Saturable Mechanism: Possible Involvement of Multidrug Resistance and Monocarboxylic Acid Transporters
Drug Metab Dispos 2002 30: 513-518. [Abstract] [Full Text] [PDF]  

Maohe Yan, Leslie T. Webster, Jr., and Jeffrey L. Blumer

3-O-Methyldobutamine, a Major Metabolite of Dobutamine in Humans
Drug Metab Dispos 2002 30: 519-524. [Abstract] [Full Text] [PDF]  

James M. Rae, Nadia V. Soukhova, David A. Flockhart, and Zeruesenay Desta

Triethylenethiophosphoramide Is a Specific Inhibitor of Cytochrome P450 2B6: Implications for Cyclophosphamide Metabolism
Drug Metab Dispos 2002 30: 525-530. [Abstract] [Full Text] [PDF]  

Joanna M. Little, Lisa Williams, Jing Xu, and Anna Radominska-Pandya

Glucuronidation of the Dietary Fatty Acids, Phytanic Acid and Docosahexaenoic Acid, by Human UDP-Glucuronosyltransferases
Drug Metab Dispos 2002 30: 531-533. [Abstract] [Full Text] [PDF]  

Hiroyoshi Nakamura, Hiromitsu Nakasa, Itsuko Ishii, Noritaka Ariyoshi, Takashi Igarashi, Shigeru Ohmori, and Mitsukazu Kitada

Effects of Endogenous Steroids on CYP3A4-Mediated Drug Metabolism by Human Liver Microsomes
Drug Metab Dispos 2002 30: 534-540. [Abstract] [Full Text] [PDF]  

Mingxing Xie, Dongfang Yang, Lan Liu, Bob Xue, and Bingfang Yan

Human and Rodent Carboxylesterases: Immunorelatedness, Overlapping Substrate Specificity, Differential Sensitivity to Serine Enzyme Inhibitors, and Tumor-Related Expression
Drug Metab Dispos 2002 30: 541-547. [Abstract] [Full Text] [PDF]  

Ting Su, Qing-Yu Zhang, Jianhua Zhang, Pam Swiatek, and Xinxin Ding

Expression of the Rat CYP2A3 Gene in Transgenic Mice
Drug Metab Dispos 2002 30: 548-552. [Abstract] [Full Text] [PDF]  

G. S. J. Mannens, C. A. W. Snel, J. Hendrickx, T. Verhaeghe, L. Le Jeune, W. Bode, L. van Beijsterveldt, K. Lavrijsen, J. Leempoels, N. Van Osselaer, A. Van Peer, and W. Meuldermans

The Metabolism and Excretion of Galantamine in Rats, Dogs, and Humans
Drug Metab Dispos 2002 30: 553-563. [Abstract] [Full Text] [PDF]  

U. Kristina Walle and Thomas Walle

Induction of Human UDP-Glucuronosyltransferase UGT1A1 by FlavonoidsStructural Requirements
Drug Metab Dispos 2002 30: 564-569. [Abstract] [Full Text] [PDF]  

Sharon L. Ripp, Jennifer L. Fitzpatrick, Jeffrey M. Peters, and Russell A. Prough

Induction of CYP3A Expression by Dehydroepiandrosterone: Involvement of the Pregnane X Receptor
Drug Metab Dispos 2002 30: 570-575. [Abstract] [Full Text] [PDF]  

Yoko Otake, Faye Hsieh, and Thomas Walle

Glucuronidation versus Oxidation of the Flavonoid Galangin by Human Liver Microsomes and Hepatocytes
Drug Metab Dispos 2002 30: 576-581. [Abstract] [Full Text] [PDF]  

Connie A. Meloche, Vyas Sharma, Stellan Swedmark, Paul Andersson, and Charles N. Falany

Sulfation of Budesonide by Human Cytosolic Sulfotransferase, Dehydroepiandrosterone-Sulfotransferase (DHEA-ST)
Drug Metab Dispos 2002 30: 582-585. [Abstract] [Full Text] [PDF]  

Prajakti A. Kothare and Cheryl L. Zimmerman

Intestinal Metabolism: The Role of Enzyme Localization in Phenol Metabolite Kinetics
Drug Metab Dispos 2002 30: 586-594. [Abstract] [Full Text] [PDF]  

Kenda A. Marcucci, Robin E. Pearce, Charles Crespi, Dorothy T. Steimel, J. Steven Leeder, and Andrea Gaedigk

Characterization of Cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 Activities toward Model CYP2D6 Substrates Dextromethorphan, Bufuralol, and Debrisoquine
Drug Metab Dispos 2002 30: 595-601. [Abstract] [Full Text] [PDF]  

Mitsuo Miyazawa, Masaki Shindo, and Tsutomu Shimada

Metabolism of (+)- and ()-Limonenes to Respective Carveols and Perillyl Alcohols by CYP2C9 and CYP2C19 in Human Liver Microsomes
Drug Metab Dispos 2002 30: 602-607. [Abstract] [Full Text] [PDF]  

Accelerated Communication:

Pankaj B. Desai, Srikanth C. Nallani, Rucha S. Sane, Linda B. Moore, Bryan J. Goodwin, Donna J. Buckley, and Arthur R. Buckley

Induction of Cytochrome P450 3A4 in Primary Human Hepatocytes and Activation of the Human Pregnane X Receptor by Tamoxifen and 4-Hydroxytamoxifen
Drug Metab Dispos 2002 30: 608-612. [Abstract] [Full Text] [PDF]  

Short Communications:

Jouko Savolainen, Jeffrey E. Edwards, Michael E. Morgan, Patrick J. McNamara, and Bradley D. Anderson

Effects of a P-Glycoprotein Inhibitor on Brain and Plasma Concentrations of Anti-Human Immunodeficiency Virus Drugs Administered in Combination in Rats
Drug Metab Dispos 2002 30: 479-482. [Abstract] [Full Text] [PDF]  

Stephanie L. Born, Douglas Caudill, Kristine L. Fliter, and Michael P. Purdon

Identification of the Cytochromes P450 That Catalyze Coumarin 3,4-Epoxidation and 3-Hydroxylation
Drug Metab Dispos 2002 30: 483-487. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.