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June 2002; 30 (6)   [Index by Author]  [Cover Caption]
       Articles
       Short Communications
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Articles:

Hoffman B. M. Lantum, Raymond B. Baggs, Daria M. Krenitsky, Philip G. Board, and M. W. Anders
Immunohistochemical Localization and Activity of Glutathione Transferase Zeta (GSTZ1-1) in Rat Tissues
Drug Metab Dispos 2002 30: 616-625. [Abstract] [Full Text] [PDF]  

Céline M. Laffont, Pierre-Louis Toutain, Michel Alvinerie, and Alain Bousquet-Mélou
Intestinal Secretion Is a Major Route for Parent Ivermectin Elimination in the Rat
Drug Metab Dispos 2002 30: 626-630. [Abstract] [Full Text] [PDF]  

Xia Wen, Jun-Sheng Wang, Janne T. Backman, Jouko Laitila, and Pertti J. Neuvonen
Trimethoprim and Sulfamethoxazole are Selective Inhibitors of CYP2C8 and CYP2C9, Respectively
Drug Metab Dispos 2002 30: 631-635. [Abstract] [Full Text] [PDF]  

Miki Nakajima, Eriko Tanaka, Tomo Kobayashi, Noriko Ohashi, Toshiyuki Kume, and Tsuyoshi Yokoi
Imipramine N-Glucuronidation in Human Liver Microsomes: Biphasic Kinetics and Characterization of UDP-Glucuronosyltransferase Isoforms
Drug Metab Dispos 2002 30: 636-642. [Abstract] [Full Text] [PDF]  

Stefan E. H. Alexson, Margareta Diczfalusy, Magnus Halldin, and Stellan Swedmark
Involvement of Liver Carboxylesterases in the In Vitro Metabolism of Lidocaine
Drug Metab Dispos 2002 30: 643-647. [Abstract] [Full Text] [PDF]  

Cuyue Tang, Yuh Lin, A. David Rodrigues, and Jiunn H. Lin
Effect of Albumin on Phenytoin and Tolbutamide Metabolism in Human Liver Microsomes: An Impact More Than Protein Binding
Drug Metab Dispos 2002 30: 648-654. [Abstract] [Full Text] [PDF]  

Jill S. Warrington, Lisa L. von Moltke, Richard I. Shader, and David J. Greenblatt
In Vitro Biotransformation of Sildenafil (Viagra) in the Male Rat: The Role of CYP2C11
Drug Metab Dispos 2002 30: 655-657. [Abstract] [Full Text] [PDF]  

Jens Koehler, Thomas Kuehnel, Frieder Kees, Klaus Hoecherl, and Horst F. Grobecker
Comparison of Bioavailability and Metabolism with Two Commercial Formulations of Cyclosporine A in Rats
Drug Metab Dispos 2002 30: 658-662. [Abstract] [Full Text] [PDF]  

Wenjiang Zhang, Yamini Ramamoorthy, Rachel F. Tyndale, Stanley D. Glick, Isabelle M. Maisonneuve, Martin E. Kuehne, and Edward M. Sellers
Metabolism of 18-Methoxycoronaridine, an Ibogaine Analog, to 18-Hydroxycoronaridine by Genetically Variable CYP2C19
Drug Metab Dispos 2002 30: 663-669. [Abstract] [Full Text] [PDF]  

Sreeraj Macha and Ashim K. Mitra
Ocular Disposition of Ganciclovir and Its Monoester Prodrugs following Intravitreal Administration Using Microdialysis
Drug Metab Dispos 2002 30: 670-675. [Abstract] [Full Text] [PDF]  

Michael C. Kohn, Ronald L. Melnick, Frank Ye, and Christopher J. Portier
Pharmacokinetics of Sodium Nitrite-Induced Methemoglobinemia in the Rat
Drug Metab Dispos 2002 30: 676-683. [Abstract] [Full Text] [PDF]  

Rita A. Halpin, Arturo G. Porras, Leslie A. Geer, Margaret R. Davis, Donghui Cui, George A. Doss, Eric Woolf, Donald Musson, Catherine Matthews, Ralph Mazenko, Jules I. Schwartz, Kenneth C. Lasseter, Kamlesh P. Vyas, and Thomas A. Baillie
The Disposition and Metabolism of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Human Subjects
Drug Metab Dispos 2002 30: 684-693. [Abstract] [Full Text] [PDF]  

Daniel C. Kemp, Peter W. Fan, and Jeffrey C. Stevens
Characterization of Raloxifene Glucuronidation in Vitro: Contribution of Intestinal Metabolism to Presystemic Clearance
Drug Metab Dispos 2002 30: 694-700. [Abstract] [Full Text] [PDF]  

Qin Mei, Cuyue Tang, Yuh Lin, Thomas H. Rushmore, and Magang Shou
Inhibition Kinetics of Monoclonal Antibodies against Cytochromes P450
Drug Metab Dispos 2002 30: 701-708. [Abstract] [Full Text] [PDF]  

Ute M. Kent, Michael Aviram, Mira Rosenblat, and Paul F. Hollenberg
The Licorice Root Derived Isoflavan Glabridin Inhibits the Activities of Human Cytochrome P450S 3A4, 2B6, and 2C9
Drug Metab Dispos 2002 30: 709-715. [Abstract] [Full Text] [PDF]  

Lee Koetzner and James H. Woods
Characterization of Butyrylcholinesterase Antagonism of Cocaine-Induced Hyperactivity
Drug Metab Dispos 2002 30: 716-723. [Abstract] [Full Text] [PDF]  

Lee Koetzner and James H. Woods
Characterization of Equine Butyrylcholinesterase Disposition in the Mouse
Drug Metab Dispos 2002 30: 724-730. [Abstract] [Full Text] [PDF]  

Virginie Charasson, Marie-Christine Haaz, and Jacques Robert
Determination of Drug Interactions Occurring with the Metabolic Pathways of Irinotecan
Drug Metab Dispos 2002 30: 731-733. [Abstract] [Full Text] [PDF]  

Brian T. Ethell, Sean Ekins, Jibo Wang, and Brian Burchell
Quantitative Structure Activity Relationships for the Glucuronidation of Simple Phenols by Expressed Human UGT1A6 and UGT1A9
Drug Metab Dispos 2002 30: 734-738. [Abstract] [Full Text] [PDF]  

Hye Chin Chung, So Hee Kim, Myung Gull Lee, and Sang Geon Kim
Increase in Urea in Conjunction with L-Arginine Metabolism in the Liver Leads to Induction of Cytochrome P450 2E1 (CYP2E1): The Role of Urea in CYP2E1 Induction by Acute Renal Failure
Drug Metab Dispos 2002 30: 739-746. [Abstract] [Full Text] [PDF]  

Philippe Claud, Yves Artur, and Romuald Laine
In Vitro Metabolism of Tresperimus by Human Vascular Semicarbazide-Sensitive Amine Oxidase
Drug Metab Dispos 2002 30: 747-755. [Abstract] [Full Text] [PDF]  

Short Communications:

Kenji Toide, Yoshiki Takahashi, Hiroshi Yamazaki, Yoshiaki Terauchi, Toshihiko Fujii, Andrew Parkinson, and Tetsuya Kamataki
Hepatocyte Nuclear Factor-1alpha Is a Causal Factor Responsible for Interindividual Differences in the Expression of UDP-Glucuronosyltransferase 2B7 mRNA in Human Livers
Drug Metab Dispos 2002 30: 613-615. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Immunohistochemical detection of GSTZ1-1 in rat lung, bladder, and prostate gland. See the article by Lantum et al. on page 616 of this issue.



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