Articles:

David Stepensky, Michael Friedman, Itamar Raz, and Amnon Hoffman

Pharmacokinetic-Pharmacodynamic Analysis of the Glucose-Lowering Effect of Metformin in Diabetic Rats Reveals First-Pass Pharmacodynamic Effect
Drug Metab Dispos 2002 30: 861-868. [Abstract] [Full Text] [PDF]  

H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard, and Elizabeth M. J. Gillam

Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4'-Hydroxy and N-Desmethyl Metabolites and Isomerization of trans-4-Hydroxytamoxifen
Drug Metab Dispos 2002 30: 869-874. [Abstract] [Full Text] [PDF]  

Kirk A. Tacka, James C. Dabrowiak, Jerry Goodisman, and Abdul-Kader Souid

Kinetic Analysis of the Reactions of 4-Hydroperoxycyclophosphamide and Acrolein With Glutathione, Mesna, and Wr-1065
Drug Metab Dispos 2002 30: 875-882. [Abstract] [Full Text] [PDF]  

J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall, and Steven A. Wrighton

Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
Drug Metab Dispos 2002 30: 883-891. [Abstract] [Full Text] [PDF]  

Yoshihiro Shibata, Hiroyuki Takahashi, Masato Chiba, and Yasuyuki Ishii

Prediction of Hepatic Clearance and Availability by Cryopreserved Human Hepatocytes: An Application of Serum Incubation Method
Drug Metab Dispos 2002 30: 892-896. [Abstract] [Full Text] [PDF]  

Jaya Bharathi Vaidyanathan and Thomas Walle

Glucuronidation and Sulfation of the Tea Flavonoid ()-Epicatechin by the Human and Rat Enzymes
Drug Metab Dispos 2002 30: 897-903. [Abstract] [Full Text] [PDF]  

Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito, and Yuichi Sugiyama

Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
Drug Metab Dispos 2002 30: 904-910. [Abstract] [Full Text] [PDF]  

Hongbing Wang, Brian Chanas, and Burhan I. Ghanayem

Cytochrome P450 2E1 (CYP2E1) is Essential for Acrylonitrile Metabolism to Cyanide: Comparative Studies Using CYP2E1-Null and Wild-Type Mice
Drug Metab Dispos 2002 30: 911-917. [Abstract] [Full Text] [PDF]  

Hao Xiong, Kouichi Yoshinari, Kim L. R. Brouwer, and Masahiko Negishi

Role of Constitutive Androstane Receptor in the In Vivo Induction of Mrp3 and CYP2B1/2 by Phenobarbital
Drug Metab Dispos 2002 30: 918-923. [Abstract] [Full Text] [PDF]  

J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget, and P. Augustijns

Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
Drug Metab Dispos 2002 30: 924-930. [Abstract] [Full Text] [PDF]  

Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi, and Masanao Katagiri

Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
Drug Metab Dispos 2002 30: 931-936. [Abstract] [Full Text] [PDF]  

Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt, and David C. Evans

Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
Drug Metab Dispos 2002 30: 937-943. [Abstract] [Full Text] [PDF]  

Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda, and Yasushi Yamazoe

Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
Drug Metab Dispos 2002 30: 944-949. [Abstract] [Full Text] [PDF]  

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