Articles:

Nathan J. Cherrington, Angela L. Slitt, Jonathan M. Maher, Xiao-Xue Zhang, Jun Zhang, Wendong Huang, Yu-Jui Yvonne Wan, David D. Moore, and Curtis D. Klaassen

INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 (MRP3) IN VIVO IS INDEPENDENT OF CONSTITUTIVE ANDROSTANE RECEPTOR
Drug Metab Dispos 2003 31: 1315-1319. [Abstract] [Full Text] [PDF]  

Elizabeth M. Laurenzana, Kelly A. Byrnes-Blake, Alessandra Milesi-Hallé, W. Brooks Gentry, D. Keith Williams, and S. Michael Owens

USE OF ANTI-(+)-METHAMPHETAMINE MONOCLONAL ANTIBODY TO SIGNIFICANTLY ALTER (+)-METHAMPHETAMINE AND (+)-AMPHETAMINE DISPOSITION IN RATS
Drug Metab Dispos 2003 31: 1320-1326. [Abstract] [Full Text] [PDF]  

Mark P. Grillo, Charles G. Knutson, Phillip E. Sanders, Daniel J. Waldon, Fengmei Hua, and Joseph A. Ware

STUDIES ON THE CHEMICAL REACTIVITY OF DICLOFENAC ACYL GLUCURONIDE WITH GLUTATHIONE: IDENTIFICATION OF DICLOFENAC-S-ACYL-GLUTATHIONE IN RAT BILE
Drug Metab Dispos 2003 31: 1327-1336. [Abstract] [Full Text] [PDF]  

Supratim Choudhuri, Nathan J. Cherrington, Ning Li, and Curtis D. Klaassen

CONSTITUTIVE EXPRESSION OF VARIOUS XENOBIOTIC AND ENDOBIOTIC TRANSPORTER mRNAs IN THE CHOROID PLEXUS OF RATS
Drug Metab Dispos 2003 31: 1337-1345. [Abstract] [Full Text] [PDF]  

Qing-Yu Zhang, Debbie Dunbar, and Laurence S. Kaminsky

CHARACTERIZATION OF MOUSE SMALL INTESTINAL CYTOCHROME P450 EXPRESSION
Drug Metab Dispos 2003 31: 1346-1351. [Abstract] [Full Text] [PDF]  

Ping Lu, Michael L. Schrag, Donald E. Slaughter, Conrad E. Raab, Magang Shou, and A. David Rodrigues

MECHANISM-BASED INHIBITION OF HUMAN LIVER MICROSOMAL CYTOCHROME P450 1A2 BY ZILEUTON, A 5-LIPOXYGENASE INHIBITOR
Drug Metab Dispos 2003 31: 1352-1360. [Abstract] [Full Text] [PDF]  

Gwendolyn E. Kuehl and Sharon E. Murphy

N-GLUCURONIDATION OF NICOTINE AND COTININE BY HUMAN LIVER MICROSOMES AND HETEROLOGOUSLY EXPRESSED UDP-GLUCURONOSYLTRANSFERASES
Drug Metab Dispos 2003 31: 1361-1368. [Abstract] [Full Text] [PDF]  

John P. O'Donnell, Deepak K. Dalvie, Amit S. Kalgutkar, and R. Scott Obach

MECHANISM-BASED INACTIVATION OF HUMAN RECOMBINANT P450 2C9 BY THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG SUPROFEN
Drug Metab Dispos 2003 31: 1369-1377. [Abstract] [Full Text] [PDF]  

Hai-Lin Fang, Sarita Shenoy, Zhengbo Duanmu, Thomas A. Kocarek, and Melissa Runge-Morris

TRANSACTIVATION OF GLUCOCORTICOID-INDUCIBLE RAT ARYL SULFOTRANSFERASE (SULT1A1) GENE TRANSCRIPTION
Drug Metab Dispos 2003 31: 1378-1381. [Abstract] [Full Text] [PDF]  

E. J. Perkins, J. W. Cramer, N. A. Farid, M. G. Gadberry, D. A. Jackson, E. L. Mattiuz, D. D. O'Bannon, H. J. Weiss, W. J. Wheeler, P. G. Wood, and K. C. Cassidy

PRECLINICAL CHARACTERIZATION OF 2-[3-[3-[(5-ETHYL-4'-FLUORO-2-HYDROXY[1,1'-BIPHENYL]-4-YL)OXY]PROPOXY]-2-PROPYLPHENOXY]BENZOIC ACID METABOLISM: IN VITRO SPECIES COMPARISON AND IN VIVO DISPOSITION IN RATS
Drug Metab Dispos 2003 31: 1382-1390. [Abstract] [Full Text] [PDF]  

Parnali Chatterjee and Michael R. Franklin

HUMAN CYTOCHROME P450 INHIBITION AND METABOLIC-INTERMEDIATE COMPLEX FORMATION BY GOLDENSEAL EXTRACT AND ITS METHYLENEDIOXYPHENYL COMPONENTS
Drug Metab Dispos 2003 31: 1391-1397. [Abstract] [Full Text] [PDF]  

Donald Slaughter, Norihiro Takenaga, Ping Lu, Carol Assang, Deborah J. Walsh, Byron H. Arison, Donghui Cui, Rita A. Halpin, Leslie A. Geer, Kamlesh P. Vyas, and Thomas A. Baillie

METABOLISM OF ROFECOXIB IN VITRO USING HUMAN LIVER SUBCELLULAR FRACTIONS
Drug Metab Dispos 2003 31: 1398-1408. [Abstract] [Full Text] [PDF]  

Hiroyoshi Hayakawa, Yoko Fukushima, Hiroshi Kato, Hiroyuki Fukumoto, Takumi Kadota, Hiroyuki Yamamoto, Hiroyuki Kuroiwa, Junko Nishigaki, and Akira Tsuji

METABOLISM AND DISPOSITION OF NOVEL DES-FLUORO QUINOLONE GARENOXACIN IN EXPERIMENTAL ANIMALS AND AN INTERSPECIES SCALING OF PHARMACOKINETIC PARAMETERS
Drug Metab Dispos 2003 31: 1409-1418. [Abstract] [Full Text] [PDF]  

Richard S. Geary, Rosie Z. Yu, Tanya Watanabe, Scott P. Henry, Greg E. Hardee, Alfred Chappell, John Matson, Henri Sasmor, Len Cummins, and Arthur A. Levin

PHARMACOKINETICS OF A TUMOR NECROSIS FACTOR- PHOSPHOROTHIOATE 2'-O-(2-METHOXYETHYL) MODIFIED ANTISENSE OLIGONUCLEOTIDE: COMPARISON ACROSS SPECIES
Drug Metab Dispos 2003 31: 1419-1428. [Abstract] [Full Text] [PDF]  

Mark P. Grillo and Fengmei Hua

IDENTIFICATION OF ZOMEPIRAC-S-ACYL-GLUTATHIONE IN VITRO IN INCUBATIONS WITH RAT HEPATOCYTES AND IN VIVO IN RAT BILE
Drug Metab Dispos 2003 31: 1429-1436. [Abstract] [Full Text] [PDF]  

Raju Subramanian, Charles C. Lin, Jonathan Z. Ho, Steven M. Pitzenberger, Maria V. Silva-Elipe, Christopher R. Gibson, Matthew P. Braun, Xiao Yu, James L. Yergey, and Rominder Singh

BIOACTIVATION OF THE 3-AMINO-6-CHLOROPYRAZINONE RING IN A THROMBIN INHIBITOR LEADS TO NOVEL DIHYDRO-IMIDAZOLE AND IMIDAZOLIDINE DERIVATIVES: STRUCTURES AND MECHANISM USING ¹³C-LABELS, MASS SPECTROMETRY, AND NMR
Drug Metab Dispos 2003 31: 1437-1447. [Abstract] [Full Text] [PDF]  

Chyung S. Cook, Loren M. Berry, Roy H. Bible, Jeremy D. Hribar, Elisabeth Hajdu, and Norman W. Liu

PHARMACOKINETICS AND METABOLISM OF [¹⁴C]EPLERENONE AFTER ORAL ADMINISTRATION TO HUMANS
Drug Metab Dispos 2003 31: 1448-1455. [Abstract] [Full Text] [PDF]  

Short Communications:

Aby Joiakim, Patricia A. Mathieu, Christine Palermo, Thomas A. Gasiewicz, and John J. Reiners, Jr.

THE JUN N-TERMINAL KINASE INHIBITOR SP600125 IS A LIGAND AND ANTAGONIST OF THE ARYL HYDROCARBON RECEPTOR
Drug Metab Dispos 2003 31: 1279-1282. [Abstract] [Full Text] [PDF]  

Takashi Furuta, Atsushi Suzuki, Chieko Mori, Hiromi Shibasaki, Akitomo Yokokawa, and Yasuji Kasuya

EVIDENCE FOR THE VALIDITY OF CORTISOL 6ß-HYDROXYLATION CLEARANCE AS A NEW INDEX FOR IN VIVO CYTOCHROME P450 3A PHENOTYPING IN HUMANS
Drug Metab Dispos 2003 31: 1283-1287. [Abstract] [Full Text] [PDF]  

Thomas Walle and U. Kristina Walle

THE ß-D-GLUCOSIDE AND SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 (SGLT1)-INHIBITOR PHLORIDZIN IS TRANSPORTED BY BOTH SGLT1 AND MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS 1/2
Drug Metab Dispos 2003 31: 1288-1291. [Abstract] [Full Text] [PDF]  

Chi-Yuan Wu and Leslie Z. Benet

DISPOSITION OF TACROLIMUS IN ISOLATED PERFUSED RAT LIVER: INFLUENCE OF TROLEANDOMYCIN, CYCLOSPORINE, AND GG918
Drug Metab Dispos 2003 31: 1292-1295. [Abstract] [Full Text] [PDF]  

Shirley Teng, Veronika Jekerle, and Micheline Piquette-Miller

INDUCTION OF ABCC3 (MRP3) BY PREGNANE X RECEPTOR ACTIVATORS
Drug Metab Dispos 2003 31: 1296-1299. [Abstract] [Full Text] [PDF]  

Bennett Ma, Magang Shou, and Michael L. Schrag

SOLVENT EFFECT ON cDNA-EXPRESSED HUMAN SULFOTRANSFERASE (SULT) ACTIVITIES IN VITRO
Drug Metab Dispos 2003 31: 1300-1305. [Abstract] [Full Text] [PDF]  

Jill S. Warrington, Lisa L. Von Moltke, Jerold S. Harmatz, Richard I. Shader, and David J. Greenblatt

THE EFFECT OF AGE ON SILDENAFIL BIOTRANSFORMATION IN RAT AND MOUSE LIVER MICROSOMES
Drug Metab Dispos 2003 31: 1306-1309. [Abstract] [Full Text] [PDF]  

Viola Tamási, Eszter Hazai, Margareta Porsmyr-Palmertz, Magnus Ingelman-Sundberg, László Vereczkey, and Katalin Monostory

GYKI-47261, A NEW AMPA [2-AMINO-3-(3-HYDROXYMETHYLISOXAZOLE-4-YL)PROPIONIC ACID] ANTAGONIST, IS A CYP2E1 INDUCER
Drug Metab Dispos 2003 31: 1310-1314. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Wanping Geng

A METHOD FOR IDENTIFICATION OF INHIBITION MECHANISM AND ESTIMATION OF K_I IN IN VITRO ENZYME INHIBITION STUDY
Drug Metab Dispos 2003 31: 1456-1457. [Full Text] [PDF]  

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